ENDOPHENOTYPES

作品数：6被引量：8H指数：2
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相关领域：医药卫生生物学更多>>
相关期刊：《Quantitative Biology》《Science Bulletin》《Neuroscience Bulletin》《World Journal of Psychiatry》更多>>
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Integrating brain imaging endophenotypes with GWAS for Alzheimer’s disease
《Quantitative Biology》2021年第2期185-200,共16页Katherine AKnutson Wei Pan 
NIH grants T32GM108557,R01AG065636,R01HL116720,R01GM113250 and R01GM126002;by the Minnesota Supercomputing Institute at the University of Minnesota.
Background:Genome wide association studies(GWAS)have identified many genetic variants associated with increased risk of Alzheimer^disease(AD).These susceptibility loci may effect AD indirectly through a combination of...
关键词：aSPU test Mendelian randomization MRI SPU tests Sum test TWAS 
Translating Interdisciplinary Research on Language Learning into Identifying Specific Learning Disabilities in Verbally Gifted and Average Children and Youth
《Journal of Behavioral and Brain Science》2017年第6期227-246,共20页Ruby Dawn Lyman Elizabeth Sanders Robert D. Abbott Virginia W. Berninger 
The current research was grounded in prior interdisciplinary research that showed cognitive ability (verbal ability for translating cognitions into oral language) and multiple-working memory endophenotypes (behavioral...
关键词：Defining SPECIFIC LEARNING DISABILITIES (SLDs) Diagnosing SPECIFIC LEARNING DISABILITIES in Written LANGUAGE (SLDs-WL) Verbal GIFTEDNESS Multi-Component Working Memory ENDOPHENOTYPES LANGUAGE LEARNING Mechanism Translation Science for Diagnosis of SLDs 
New findings in the genetics of schizophrenia被引量：2
《World Journal of Psychiatry》2013年第3期57-61,共5页Ladislav Hosak 
Supported by The Research Grant NT14504/2013 from the Internal Grant Agency of the Ministry of Health of the Czech Republic
New findings in schizophrenia genetics are based on genome-wide association studies(GWAS), research into DNA copy number variations(CNVs), and endophenotypes. More than 70 genes have recently been suspected to be invo...
关键词：SCHIZOPHRENIA GENETICS GENOME-WIDE association study COPY number variations ENDOPHENOTYPES 
Neuropsychological study of patients with obsessive-compulsive disorder and their parents in China: searching for potential endophenotypes被引量：4
《Neuroscience Bulletin》2012年第5期475-482,共8页Bin Li Jin-Hua Sun Tao Li Yan-Chun Yang 
supported by the National Natural Science Foundation for Distinguished Young Scholars of China (30125014)
Objective The existence of neuropsychological deficits has been implicated in obsessive-compulsive disorder （OCD）, particularly memory, attention, and executive functions. However, few studies have focused on neurop...
关键词：obsessive-compulsive disorder neuropsychological tests memory deficits problem-solving ability endophe-notype 
Recent developments in neuropsychological endophenotypes for schizophrenia: Development of the MATRICS battery, liability syndromes and the near future被引量：1
《Chinese Science Bulletin》2011年第32期3385-3393,共9页STONE William S HSI Xiaolu 
supported in part by Ortho-McNeil Janssen Scientific Affairs, LLC;by National Institute of Mental Health Grant RO1-MH065562 (COGS; Consortium on the Genetics of Schizophrenia)
Cognitive deficits are now recognized widely as core features of schizophrenia, and as major contributors to the clinical outcome of the disorder. They are also studied widely as 'endophenotypes', reflecting a growing...
关键词：精神分裂症 心理测验 综合征 电池 神经 稳定 责任 认知功能 
A family study of endophenotypes for psychosis within an early intervention programme in Hong Kong: Rationale and preliminary findings被引量：2
《Chinese Science Bulletin》2011年第32期3394-3397,共4页LUI Simon S Y SHAM Pak CHAN Raymond C K CHEUNG Eric F C 
supported by the Project-Oriented Hundred Talents Programme (O7CX031003);the Knowledge Innovation Project of the Chinese Academy of Sciences (KSCX2-YW-R-131, KSCX2-EW-J-8);a grant from the National Science Fund for Distinguished Young Scholars(81088001) to Raymond Chan
The study of endophenotypes may be a viable strategy to tackle the genetic complexity and phenotypic heterogeneity of psychosis, but this research direction is relatively under-developed in China as compared to Wester...
关键词：精神病患者 稳定 家庭 早期 原理 预计 香港 面部表情识别 
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