This work was supported by grants from the National Natural Science Foundation of China(No.81771749 and No.81771748)。
Osteoarthritis(OA)is a debilitating disease with limited treatment options.[1]Autophagy serves as an important protective mechanism against the deterioration of cartilage and is negatively regulated by the mammalian t...
Background Celastrol is a major active component of Tripterygium wilfordii named "Thunder God Vine", which is widely used to treat rheumatoid arthritis in China. The present study aims to demonstrate that celastrol ...