supported by the National Key R&D Program of China(2022YFF1000100,2023YFD1300300);the National Natural Science Foundation of China(31572388,31972525);the China Agriculture Research System of MOF and MARA(CARS-41)。
Background Chickens and ducks are vital sources of animal protein for humans.Recent pangenome studies suggest that a single genome is insufficient to represent the genetic information of a species,highlighting the nee...
This study was reviewed and approved by the Ethic Committee of Medical College of Henan Vocational University of Science and Technology(Approval No.HVUYL414101416920231017001);all participants signed a written informed consent.
BACKGROUND Centromere protein A(CENPA)exhibits an increased expression level in primary human rectal cancer tissues,but its role has not been investigated.AIM To clarify the specific role and mechanism of CENPA in rec...
supported by the National Natural Science Foundation of China(grant no.32100501);the Innovation Program of Chinese Academy of Agricultural Sciences.
Dear Editor,Centromeres,the basis for cell division,offer essential insights into cell dynamics,genome stability,and evolutionary processes(McKinley and Cheeseman,2016).Because of ultra-high complexity,high-quality se...
supported by the National Key R&D Program of China(Grant No.2022YFC3400300);the National Natural Science Foundation of China(Grant Nos.32125009,32400520,32422019,62172325,32070663,32200510);the Natural Science Foundation of Shaanxi Province(Grant No.2024JC-JCQN-28);the Fundamental Research Funds for the Central Universities(Grant No.xzy012024088);China.
High-fidelity(HiFi)sequencing has facilitated the assembly and analysis of the most repetitive region of the genome,the centromere.Nevertheless,our current understanding of human centromeres is based on a relatively s...
supported by the National Key Research and Development Program of China(2023YFD2300703);the National Natural Science Foundation of China(32372794 and 32072653);the Science and Technology Program of Xinjiang Production and Construction Corps(2023AB050);the Fundamental Research Funds for the Central Universities(2662023YLPY008);the Ningbo Scientific and Technological Project(2021Z006).
Dear Editor,Pumpkin(Cucurbita maxima)belongs to the Cucurbita genus of the Cucurbitaceae family and is a globally cultivated vegetable crop with great economic significance.The global production and planting area of p...
supported by the National Natural Science Foundation of China(31991212);the National Key Research and Development Program of China(2022YFF1003303)。
Non-B-form DNA differs from the classic B-DNA double helix structure and plays a crucial regulatory role in replication and transcription.However,the role of non-B-form DNA in centromeres,especially in polyploid wheat...
the National Natural Science Foundation of China(31991212);the National Key Research and Development Program of China(2022YFF1003303).
The Triticum-Aegilops complex groups demonstrated high cross-affinity with each other to overcome the barriers of distant hybridization(Loureiro et al.,2023).Distant hybridization involves two distinct yet closely rel...
supported by the National Natural Science Foundation of China(32188102,32372148);Innovation Program of Chinese Academy of Agricultural Sciences,the Youth Innovation of Chinese Academy of Agricultural Sciences(Y20230C36);Guangdong Basic and Applied Basic Research Foundation(2023B1515020053);the Youth Program of Guangdong Basic and Applied Research(2021A1515111123)。
Rice(Oryza sativa)is a significant crop worldwide with a genome shaped by various evolutionary factors.Rice centromeres are crucial for chromosome segregation,and contain some unreported genes.Due to the diverse and c...
supported by the National Natural Science Foundation of China (32170645);the National Key Research and Development Program of China (2021YFF1000900).
Centromere positioning and organization are crucial for genome evolution;however,research on centro-mere biology is largely influenced by the quality of available genome assemblies.Here,we combined Oxford Nanopore and...
supported by grants from the Ministry of Science and Technology of China(2022YFA1303100,2022YFA0806800,2022YFA1302700,and 2017YFA0503600);the National Natural Science Foundation of China(32090040,92254302,92153302,32170733,31621002,and 22177106);the Strategic Priority Research Program of the Chinese Academy of Sciences(XDB19040000 and XDB37010105);the Ministry of Education(IRT_17R102,20113402130010,and YD2070006001).
Shugoshin-1(Sgo1)is necessary for maintaining sister centromere cohesion and ensuring accurate chromosome segregation during mitosis.It has been reported that the localization of Sgo1 at the centromere is dependent on...