CENTROMERE

作品数:60被引量:177H指数:7
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相关领域:生物学医药卫生更多>>
相关作者:谭立明舒艳谭毅曾婷婷余建林更多>>
相关机构:南昌大学第二附属医院重庆医科大学内蒙古大学中山大学附属第一医院更多>>
相关期刊:《Journal of Animal Science and Biotechnology》《Journal of Ocean University of China》《Science China(Life Sciences)》《Frontiers in Biology》更多>>
相关基金:国家自然科学基金国家重点基础研究发展计划中国博士后科学基金福建省自然科学基金更多>>
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Near telomere-to-telomere genome assemblies of Silkie Gallus gallus and Mallard Anas platyrhynchos restored the structure of chromosomes and “missing” genes in birds
《Journal of Animal Science and Biotechnology》2025年第2期517-530,共14页Qiangsen Zhao Zhongtao Yin Zhuocheng Hou 
supported by the National Key R&D Program of China(2022YFF1000100,2023YFD1300300);the National Natural Science Foundation of China(31572388,31972525);the China Agriculture Research System of MOF and MARA(CARS-41)。
Background Chickens and ducks are vital sources of animal protein for humans.Recent pangenome studies suggest that a single genome is insufficient to represent the genetic information of a species,highlighting the nee...
关键词:AVIAN CENTROMERE Missing gene Telomere-to-telomere genome 5mC methylation level 
Centromere protein A knockdown inhibits rectal cancer through O6- methylguanine DNA methyltransferase/protein tyrosine phosphatase nonreceptor type 4 axis
《World Journal of Gastrointestinal Oncology》2025年第4期347-364,共18页Ming-Jie Xin Yong Yuan 
This study was reviewed and approved by the Ethic Committee of Medical College of Henan Vocational University of Science and Technology(Approval No.HVUYL414101416920231017001);all participants signed a written informed consent.
BACKGROUND Centromere protein A(CENPA)exhibits an increased expression level in primary human rectal cancer tissues,but its role has not been investigated.AIM To clarify the specific role and mechanism of CENPA in rec...
关键词:Rectal cancer Centromere protein A O6-methylguanine DNA methyltransferase Protein tyrosine phosphatase nonreceptor type 4 PROLIFERATION INVASION 
CentIER:Accurate centromere identification for plant genomes
《Plant Communications》2024年第10期12-15,共4页Dong Xu Jinbao Yang Huaming Wen Wenle Feng Xiaohui Zhang Xingqi Hui Junyang Yue Yun Xu Fei Chen Weihua Pan 
supported by the National Natural Science Foundation of China(grant no.32100501);the Innovation Program of Chinese Academy of Agricultural Sciences.
Dear Editor,Centromeres,the basis for cell division,offer essential insights into cell dynamics,genome stability,and evolutionary processes(McKinley and Cheeseman,2016).Because of ultra-high complexity,high-quality se...
关键词:hinder INSIGHT STABILITY 
Centromere Landscapes Resolved from Hundreds of Human Genomes
《Genomics, Proteomics & Bioinformatics》2024年第5期61-71,共11页Shenghan Gao Yimeng Zhang Stephen J. Bush Bo Wang Xiaofei Yang Kai Ye 
supported by the National Key R&D Program of China(Grant No.2022YFC3400300);the National Natural Science Foundation of China(Grant Nos.32125009,32400520,32422019,62172325,32070663,32200510);the Natural Science Foundation of Shaanxi Province(Grant No.2024JC-JCQN-28);the Fundamental Research Funds for the Central Universities(Grant No.xzy012024088);China.
High-fidelity(HiFi)sequencing has facilitated the assembly and analysis of the most repetitive region of the genome,the centromere.Nevertheless,our current understanding of human centromeres is based on a relatively s...
关键词:Centromere sequence Genome evolution High-fidelity sequencing technology Higher order repeat annotation Human population 
Complete genome assembly provides insights into the centromere architecture of pumpkin(Cucurbita maxima)
《Plant Communications》2024年第9期12-15,共4页Qingguo Zeng Minghua Wei Shuai Li Haiyan Wang Changjuan Mo Li Yang Xinzheng Li Zhilong Bie Qiusheng Kong 
supported by the National Key Research and Development Program of China(2023YFD2300703);the National Natural Science Foundation of China(32372794 and 32072653);the Science and Technology Program of Xinjiang Production and Construction Corps(2023AB050);the Fundamental Research Funds for the Central Universities(2662023YLPY008);the Ningbo Scientific and Technological Project(2021Z006).
Dear Editor,Pumpkin(Cucurbita maxima)belongs to the Cucurbita genus of the Cucurbitaceae family and is a globally cultivated vegetable crop with great economic significance.The global production and planting area of p...
关键词:SIGNIFICANCE INSIGHT globally 
Non-B-form DNA is associated with centromere stability in newly-formed polyploid wheat
《Science China(Life Sciences)》2024年第7期1479-1488,共10页Congyang Yi Qian Liu Yuhong Huang Chang Liu Xianrui Guo Chaolan Fan Kaibiao Zhang Yang Liu Fangpu Han 
supported by the National Natural Science Foundation of China(31991212);the National Key Research and Development Program of China(2022YFF1003303)。
Non-B-form DNA differs from the classic B-DNA double helix structure and plays a crucial regulatory role in replication and transcription.However,the role of non-B-form DNA in centromeres,especially in polyploid wheat...
关键词:non-B-form DNA polyploid wheat CENTROMERE RETROTRANSPOSON 
Wide hybridizations reveal the robustness of functional centromeres in Triticum-Aegilops species complex lines
《Journal of Genetics and Genomics》2024年第5期570-573,共4页Yuhong Huang Qinghua Shi Chen Zhou Chunhui Wang Yang Liu Congyang Yi Handong Su Fangpu Han 
the National Natural Science Foundation of China(31991212);the National Key Research and Development Program of China(2022YFF1003303).
The Triticum-Aegilops complex groups demonstrated high cross-affinity with each other to overcome the barriers of distant hybridization(Loureiro et al.,2023).Distant hybridization involves two distinct yet closely rel...
关键词:CENTROMERE TRITICUM complex 
A centromere map based on super pan-genome highlights the structure and function of rice centromeres被引量:1
《Journal of Integrative Plant Biology》2024年第2期196-207,共12页Yang Lv Congcong Liu Xiaoxia Li Yueying Wang Huiying He Wenchuang He Wu Chen Longbo Yang Xiaofan Dai Xinglan Cao Xiaoman Yu Jiajia Liu Bin Zhang Hua Wei Hong Zhang Hongge Qian Chuanlin Shi Yue Leng Xiangpei Liu Mingliang Guo Xianmeng Wang Zhipeng Zhang Tianyi Wang Bintao Zhang Qiang Xu Yan Cui Qianqian Zhang Qiaoling Yuan Noushin Jahan Jie Ma Xiaoming Zheng Yongfeng Zhou Qian Qian Longbiao Guo Lianguang Shang 
supported by the National Natural Science Foundation of China(32188102,32372148);Innovation Program of Chinese Academy of Agricultural Sciences,the Youth Innovation of Chinese Academy of Agricultural Sciences(Y20230C36);Guangdong Basic and Applied Basic Research Foundation(2023B1515020053);the Youth Program of Guangdong Basic and Applied Research(2021A1515111123)。
Rice(Oryza sativa)is a significant crop worldwide with a genome shaped by various evolutionary factors.Rice centromeres are crucial for chromosome segregation,and contain some unreported genes.Due to the diverse and c...
关键词:CENTROMERE super pan-genome CentoO satellite repeat RICE 
High-quality Gossypium hirsutum and Gossypium barbadense genome assemblies reveal the landscape and evolution of centromeres被引量:3
《Plant Communications》2024年第2期135-150,共16页Xing Chang Xin He Jianying Li Zhenping Liu Ruizhen Pi Xuanxuan Luo Ruipeng Wang Xiubao Hu Sifan Lu Xianlong Zhang Maojun Wang 
supported by the National Natural Science Foundation of China (32170645);the National Key Research and Development Program of China (2021YFF1000900).
Centromere positioning and organization are crucial for genome evolution;however,research on centro-mere biology is largely influenced by the quality of available genome assemblies.Here,we combined Oxford Nanopore and...
关键词:genome assembly centromere architecture convergent evolution POLYPLOIDIZATION 
Sgo1 interacts with CENP-A to guide accurate chromosome segregation in mitosis
《Journal of Molecular Cell Biology》2023年第10期26-38,共13页Fengge Wu Hameed Akbar Chunyue Wang Xiao Yuan Zhen Dou McKay Mullen Liwen Niu Liang Zhang Jianye Zang Zhikai Wang Xuebiao Yao Xiaoyu Song Xing Liu 
supported by grants from the Ministry of Science and Technology of China(2022YFA1303100,2022YFA0806800,2022YFA1302700,and 2017YFA0503600);the National Natural Science Foundation of China(32090040,92254302,92153302,32170733,31621002,and 22177106);the Strategic Priority Research Program of the Chinese Academy of Sciences(XDB19040000 and XDB37010105);the Ministry of Education(IRT_17R102,20113402130010,and YD2070006001).
Shugoshin-1(Sgo1)is necessary for maintaining sister centromere cohesion and ensuring accurate chromosome segregation during mitosis.It has been reported that the localization of Sgo1 at the centromere is dependent on...
关键词:MITOSIS CENTROMERE KINETOCHORE Sgo1 CENP-A Aurora B 
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