OSTEOLYSIS

作品数：38被引量：88H指数：6
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相关领域：医药卫生更多>>
相关作者：谭艳辉邹斌华李晓娟程晓光汪学军更多>>
相关机构：广西医科大学北京丰盛医院南方医科大学苏州大学更多>>
相关期刊：《Chinese Journal of Traumatology》《Cellular & Molecular Immunology》《Acta Pharmacologica Sinica》《Open Journal of Orthopedics》更多>>
相关基金：国家自然科学基金上海市自然科学基金国家重点基础研究发展计划更多>>
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Macrophage-derived exosomes modulate wear particle-induced osteolysis via miR-3470b targeting TAB3/NF-κB signaling被引量：5
《Bioactive Materials》2023年第8期181-193,共13页Baiqi Pan Ziji Zhang Xiaoyu Wu Guoyan Xian Xuantao Hu Minghui Gu Linli Zheng Xiang Li Lingli Long Weishen Chen Puyi Sheng 
supported by the National Natural Science Foundation of China[grant numbers 82172405,81972050,81802179].
Aseptic prosthesis loosening(APL)is one of the most prevalent complications associated with arthroplasty.The main cause is the periprosthetic osteolysis induced by wear particles.However,the specific mechanisms of cro...
关键词：Aseptic prothesis loosening EXOSOME Non-coding RNA MACROPHAGE Inflammatory osteolysis 
Small extracellular vesicles derived from hypoxic preconditioned dental pulp stem cells ameliorate inflammatory osteolysis by modulating macrophage polarization and osteoclastogenesis被引量：6
《Bioactive Materials》2023年第4期326-342,共17页Jun Tian Weiyang Chen Yuhua Xiong Qianer Li Siyi Kong Mengjie Li Chunfeng Pang Yu Qiu Zhezhen Xu Qimei Gong Xi Wei 
This work was supported by National Natural Science Foundation of China(No.81870750,81970925,81900994);the Guangdong Financial Fund for High-Caliber Hospital Construction(174-2018-XMZC-0001-03-0125/D-08).
Extensive macrophage inflammatory responses and osteoclast formation are predominant during inflammatory or infective osteolysis.Mesenchymal stem cell(MSC)-derived small extracellular vesicles(MSC-sEV)have been shown ...
关键词：Dental pulp stem cells Small extracellular vesicles Macrophage OSTEOCLAST Inflammatory osteolysis 
Niobium carbide(MXene)reduces UHMWPE particle-induced osteolysis
《Bioactive Materials》2022年第2期435-448,共14页Kuo-Yang Sun Yizhang Wu Jia Xu Wenfang Xiong Wei Xu Jiawei Li Ziying Sun Zhongyang Lv XSWu Qing Jiang Hong-Ling Cai Dongquan Shi 
supported by National Key R&D Program of China(2018YFC1105904,2016YFA0201104);National Science Foundation of China(81772335,81941009,81802196,11874200);Natural Science Foundation of Jiangsu Province,China(BK20180127);Jiangsu Provincial Key Medical Talent Foundation;Six Talent Peaks Project of Jiangsu Province(WSW-079).
Joint replacement surgery is one of the orthopedic surgeries with high successful rates;however,wear debris generated from prostheses can ultimately lead to periprosthetic osteolysis and failure of the implant.The imp...
关键词：Periprosthetic osteolysis MXene Niobium carbide OSTEOCLASTOGENESIS Reactive oxygen species(ROS) 
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