supported by AFM-Telethon2013/Project 16662(to CB).
Spinal muscular atrophy(SMA)is a genetic disorder that primarily affects infants and leads to muscle weakness,atrophy,and paralysis.The main cause is the homozygous mutation or deletion of the SMN1 gene,resulting in i...
Human prion-like proteins often correspond to nucleic acid binding proteins,displaying both globular domains and long intrinsically disordered regions(IDRs)(Harrison and Shorter,2017).Their IDRs are of low complexity ...
supported by grants from the Lone Star Paralysis Foundation to GDB and by an NIH grant R01 NS081063 to GDB
The repair(sealing) of plasmalemmal damage,consisting of small holes to complete transections,is critical for cell survival,especially for neurons that rarely regenerate cell bodies.We first describe and evaluate di...
supported by an internal Quinnipiac University Grant-In-Aid to LCK between the years of 2012-2014
Neurodegenerative diseases are extremely prevalent in today’s society and,according to the World Health Organization,are currently listed as the third leading cause of death,following cancer and heart disease(Gammon...
supported by a grant from the Kyung Hee University in 2013(KHU20130548)
Following damage resulting from mechanical injury,viral infection,or autoimmunity,peripheral nerves degenerate and a variety of complications,including sensory loss,muscular paralysis,skin thinning,and a loss of tendo...
The aim of the study was to investigate the functional performance in children with spina bifida, using the Pediatric Evaluation of Disability Inventory (PEDI) to look into capacity of twen- ty-eight children with s...
a grant by Key Projects of Liaoning Province, No. 2008225009
Due to their relative abundance,stable biological properties and excellent reproductive activity,umbilical cord mesenchymal stem cells have previously been utilized for the treatment of Duchenne muscular dystrophy,whi...
Supported by the National Natural Science Foundation of China,No. 30772860
BACKGROUND:Gastrointestinal motility dysfunction in multiple organ dysfunction syndrome (MODS) has been reported to be related to damage to interstitial cells of Cajal (ICC). In the entedc nervous system, ICC and...
the grants from Shandong Medical Academy, No. 2004-023
BACKGROUND: The pathways induced/activated by mercury poisoning that lead to muscle pain remain unclear. The present study addressed the structural changes observed in the peripheral nerve following mercury poisoning...
BACKGROUND: Recent researches have demonstrated that baclofen is a commonly central anti-spasm drug. In addition, neural facilitation technique based on nerve development and neurophysiology is widely used for rehabi...