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CATHELICIDIN: 作品数：55被引量：117H指数：5; 导出分析报告; 相关领域：医药卫生更多>>; 相关作者：王义鹏于海宁李冬汪以真赖仞更多>>; 相关机构：大连理工大学中国科学院昆明医科大学浙江大学更多>>; 相关期刊：更多>>; 相关基金：国家自然科学基金山东省自然科学基金山东省优秀中青年科学家科研奖励基金国家高技术研究发展计划更多>>

血清Vaspin、cathelicidin的表达对糖尿病患儿早期肾功能改变的预测价值: 《中华养生保健》2024年第13期41-45,共5页李光贵; 目的探讨血清腹腔脂肪型丝氨酸蛋白酶抑制剂(Vaspin)、抗菌肽cathelicidin(LL-37)的表达对糖尿病患儿早期肾功能改变的预测价值。方法选取2020年7月—2023年7月遵义市第一人民医院收治的80例糖尿病住院患儿作为研究对象,依照患儿尿蛋白...; 关键词：腹腔脂肪型丝氨酸蛋白酶抑制剂抗菌肽糖尿病患儿肾功能

The Effect of Retinoic Acid on Neutrophil Innate Immune Interactions With Cutaneous Bacterial Pathogens: 《Infectious Microbes & Diseases》2024年第2期65-73,共9页Alexandra Stream Ross Corriden Simon Döhrmann Richard L.Gallo Victor Nizet Ericka L.Anderson; US National Institutes of Health grants(R01-AI145325 to VN and R37-AI052453 to VN and RLG);a BioLegend Graduate Fellowship in Immunology.; Vitamin A and its biologically active derivative,retinoic acid(RA),are important for many immune processes.RA,in particular,is essential for the development of immune cells,including neutrophils,which serve as a front...; 关键词：retinoic acid NEUTROPHIL bacterial infection Staphylococcus aureus group A Streptococcus neutrophil extracellular traps antimicrobial peptide CATHELICIDIN

黄喉拟水龟Cathelicidin基因克隆及表达分析被引量：1: 《南方农业学报》2023年第5期1559-1567,共9页魏华谭雯予吴志刚杨祖鹏张洪耀韩书煜施金谷黄德生梁静真黄钧; 广西自然科学基金项目(2018GXNSFAA138167)。; 【目的】克隆黄喉拟水龟(Mauremys mutica)Cathelicidin基因(MmCath)并分析其组织表达特征,为深入研究MmCath基因在黄喉拟水龟先天免疫中的潜在作用提供理论依据。【方法】运用RACE克隆黄喉拟水龟MmCath基因cDNA序列,利用生物信息学软...; 关键词：黄喉拟水龟 Cathelicidin基因基因克隆表达特征

NMR assisted studies on the solution structures and functions of antimicrobial peptides Dedicated to Professor Chaohui Ye on the occasion of his 80th birthday: 《Magnetic Resonance Letters》2022年第4期214-223,共10页Yaying Zhang Chunyang Cao; National Science Foundation of China(NSFC)under No.22174155,22177127 and 21977110.; Microbial resistance has now become a global public health concern,and the spread of multidrug-resistant bacteria also threatens human health.Antimicrobial peptides(AMPs)are a class of small peptides with antibacteria...; 关键词：Nuclear magnetic resonance Antimicrobial peptides CATHELICIDIN Structure Function

Bicarbonate Effects on Antibacterial Immunity and Mucus Glycobiology in the Cystic Fibrosis Lung:A Review With Selected Experimental Observations: 《Infectious Microbes & Diseases》2022年第3期103-110,共8页Ruth Siew Tzung-Lin Ou Samira Dahesh Kathryn Akong Victor Nizet; supported by NIH training fellowships 5T32HD08798 and 5K12HL141956 to RS and NIH research grant R01AI145310 to VN.; The primary defect in cystic fibrosis(CF)is abnormal chloride and bicarbonate transport in the CF transmembrane conductance regulator epithelial ion channel.The apical surface of the respiratory tract is lined by an a...; 关键词：cystic fibrosis BICARBONATE MUCUS PNEUMONIA bacterial infection NEUTROPHIL CATHELICIDIN neutrophil extracellular traps

树蛙抗菌肽Cathelicidin在毕赤酵母中的表达及抑菌活性分析被引量：7: 《农业生物技术学报》2021年第1期67-72,共6页王莲哲刘士俊刘佳乐洪军; 河南省高等学校重点科研项目计划(19A180011)。; 树蛙(Rhacophorus)抗菌肽Cathelicidin是一类具有广谱抗微生物活性的小分子多肽,在医疗、畜牧等方面有潜在应用价值,但其真核表达少有报道。本研究根据毕赤酵母(Pichia pastoris)的密码子偏爱性进行优化,合成树蛙抗菌肽Cathelicidin的...; 关键词：抗菌肽Cathelicidin 毕赤酵母抑菌活性分泌表达

Chitosan hydrogel encapsulated with LL-37 peptide promotes deep tissue injury healing in a mouse model被引量：5: 《Military Medical Research》2020年第4期409-417,共9页Xu Yang Jing-Lin Guo Jing Han Rui-Juan Si Pan-Pan Liu Zi-Rui Zhang Ai-Min Wang Ju Zhang; supported by the National Natural Science Foundation of China(No.81701838);the China Postdoctoral Science Foundation(2018M632628); Background:LL-37 peptide is a member of the human cathelicidin family,and has been shown to promote the healing of pressure ulcers.However,the low stability of this peptide within the wound environment limits its clin...; 关键词：LL-37 Chitosan hydrogel Deep tissue injury Pressure ulcer CATHELICIDIN

PDX通过P38 MAPK通路促进脓毒症性ARDS抗菌肽cathelicidin表达被引量：3: 《温州医科大学学报》2019年第7期469-474,共6页谷丽君潘静怡 MOHAMED ALI Abdullahi 金胜威; 国家自然科学基金资助项目(81570076,81870065); 目的:探究PDX对脓毒症性ARDS抗菌肽cathelicidin(CAMP)的影响及其具体机制。方法:C57BL/6小鼠行盲肠结扎穿孔术建立脓毒症模型,分为:假手术组(Sham组)、脓毒症组(CLP组)、治疗组(CLP+PDX组)、抑制剂组(CLP+PDX+SB203580组)、溶剂对照组(...; 关键词：脓毒症 PDX MAPK 抗菌肽 CATHELICIDIN

黄沙鳖抗菌肽cathelicidin基因克隆及表达特征分析被引量：3: 《南方农业学报》2019年第7期1605-1612,共8页马沙盛雪晴许飘尹贺晓晨黎姗梅韦汉英韦慕兰黄立春梁静真黄钧; 广西自然科学基金项目（2015GXNSFBA139063,2018GXNSFAA138167）;广西水产畜牧兽医局水产养殖动物病情测报专项（桂渔牧财〔2017〕23号）; 【目的】克隆黄沙鳖cathelicidin基因并分析其组织分布特征及在攻毒后的表达变化,为深入研究cathelicidin功能及在黄沙鳖先天免疫中的潜在作用提供基础数据。【方法】采用RT-PCR结合RACE克隆黄沙鳖cathelicidin基因cDNA全长序列,利用生...; 关键词：黄沙鳖抗菌肽 CATHELICIDIN 基因克隆表达特征

Cathelicidin LL-37 restoring glucocorticoid function in smoking and lipopolysaccharide-induced airway inflammation in rats被引量：7: 《Chinese Medical Journal》2019年第5期569-576,共8页Jian-Zhen Weng Yan Wang Tie-Ying Sun; National Natural Science Foundation of China (No.81300033).; Background Glucocorticoids have been widely used to treat patients with chronic obstructive pulmonary disease (COPD). Nevertheless, corticosteroid insensitivity is a major barrier to the effective treatment of COPD an...; 关键词：Chronic obstructive pulmonary disease GLUCOCORTICOID INSENSITIVITY Histone deacetylase-2 PHOSPHOINOSITIDE 3-kinase/Akt pathway

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