Tetramethylpyrazine(TMP) is a traditional Chinese herbal medicine with strong antiinflammatory and cartilage protection activities, and thus a promising candidate for treating osteoarthritis. However, TMP is rapidly c...
supported by the Key Project of Medical Science of Hebei Province(No.20170185)
Objective: To further explore the function of combine use of tetramethylpyrazine(TMP) and cisplatin(DDP) in lung carcinoma. Methods: We used the combination drug to treat Lewis lung cancer mice, investigated the expre...
supported by the National Nature Sciences Foundation of China(Nos.81073028,81130067 and 81274127)
AIM: Radiation induces an important apoptosis response in irradiated organs. The objective of this study was to investigate the radioprotective effect of tetramethylpyrazine(TMP) on irradiated lymphocytes and discover...
innovation and Technology Funds of Hong Kong;strategic Program of the Chinese University of Hong Kong
AIM: To investigate the effect of tetramethylpyrazine (ligustrazine, TMP) on the secretion of exocrine pancreas (and biliary).METHODS: In in vivo study, we investigated the effect of TMP on the secretion of pancreatic...
To test the hypotliesis of Syndrome and Treatment Pharmacokinetics (S-TPK ) , tlie authorsbeve stodied tlie pharmacokinetics of tetramethyrazine phosphate (TMPP) in healthy and blood stasis dogs byhigh performance liq...