DIPEPTIDES

作品数：38被引量：45H指数：4
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相关领域：理学生物学更多>>
相关作者：杨兵詹传郎林子敬李潇姚建年更多>>
相关机构：中国科学技术大学中国科学院更多>>
相关期刊：《Chinese Journal of Traumatology》《Chinese Journal of Natural Medicines》《Science China Chemistry》《World Journal of Gastroenterology》更多>>
相关基金：国家自然科学基金广东省大学生创新实验项目湖北省自然科学基金更多>>
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Chemical isotope labeling-assisted liquid chromatography-mass spectrometry enables sensitive and accurate determination of dipeptides and tripeptides in complex biological samples
《Chinese Chemical Letters》2024年第11期284-289,共6页Feng-Qing Huang Yu Wang Ji-Wen Wang Dai Yang Shi-Lei Wang Yuan-Ming Fan Raphael N.Alolga Lian-Wen Qi 
financially supported in part by the National Natural Science Fund of China for Distinguished Young Scholars(No.81825023);National Natural Science Foundation of China(No.82003979);Natural Science Foundation of Shanghai(No.23ZR1459100)。
Small peptides have attracted increasing attention for their unique features and diverse biological functions.Achieving rapid separation and accurate quantification,however,remains a challenge because of their low abu...
关键词：Di/tripeptides Chemical derivatization Isotope labeling Liquid chromatography tandem mass SPECTROMETRY Biliary tract cancer 
Dock-able linear and homodetic di, tri, tetra and pentapeptide library from canonical amino acids: SARS-CoV-2 Mpro as a case study
《Journal of Pharmaceutical Analysis》2023年第5期523-534,共12页Sarfraz Ahmad Muhammad Usman Mirza John F.Trant 
Peptide-based therapeutics are increasingly pushing to the forefront of biomedicine with their promise of high specificity and low toxicity.Although noncanonical residues can always be used,employing only the natural ...
关键词：DIPEPTIDES TRIPEPTIDES Tetrapeptides Pentapeptides N-to-C-terminal cyclic peptides Peptide library 
Co-assembled C13-dipeptide hydrogels by Gallic Acid (CA) and epigallocatechin gallate (EGCG) with antibacterial activity
《Food Bioscience》2022年第5期933-940,共8页Tan Hu Siyi Pan 
supported by China Agriculture Research System of MOF and MARA(CARS-26-07B);Fundamental Research Funds for the Central Universities(2662019PY016,2662020SPPY011);Hubei Province Technology Innovation Special Major Project(2018ABA072).
The self-assembled peptide-based hydrogels have been widely utilized in foods.However,the self-assembled hydrogels still have some shortages such as low mechanical properties and hydrogel stabilities.Herein,we designe...
关键词：Peptide hydrogels C_(13)-dipeptides Co-assembly Antibacterial activity 
Effect of Microwave Irradiation on Dipeptides and Proteins Derived from Silk During Solvation被引量：1
《Advanced Fiber Materials》2022年第3期448-456,共9页Na Li Ying Ma Niuniu Chen Xiaoyu Tang Shanshan Lv 
This work was supported by the National Natural Science Foundation of China[grant number:21972009];the National Key Research Program of China[grant number:2016YFA0201700/2016YFA0201701].
Silkworm silk and spider silk have been attracting numerous interests.Rapid solvation of silkworm silk protein and spider silk protein without hydrolysis of peptide bonds is highly desirable.Microwave irradiation has ...
关键词：SILK Protein PEPTIDE Peptide bond Microwave 
Carnosine concentration and expression profiles of carnosine related genes in Mytilus after beta-alanine injection被引量：1
《Journal of Oceanology and Limnology》2022年第3期1121-1134,共14页Chen PAN Zhi LIAO Jianyu HE Zhongqi GU Chunyue WANG Meihua FAN Isabella BUTTINO Baoying GUO Xiaojun YAN Xiaolin ZHANG 
Supported by the National Natural Science Foundation of China(Nos.42020104009,31671009,42076119);the Project of Zhoushan Science and Technology Bureau(No.2019F12004)。
Carnosine and its analogues are histidine-containing dipeptides(HCDs)playing diverse functions in vertebrates.However,the distribution and the metabolism of carnosine in invertebrates are still unknown.In this study,M...
关键词：Mytilus coruscus BETA-ALANINE CARNOSINE histidine-containing dipeptides TRANSCRIPTOME 
Systematic screening and structural characterization of dipeptides using offline 2D LC-LTQ-Orbitrap MS:A case study of Cordyceps sinensis
《Journal of Pharmaceutical Analysis》2022年第2期263-269,共7页Xiaodie Li Changliang Yao Yun Li Zhengming Qian c Wenlong Wei Jianqing Zhang Jiayuan Li Qirui Bi Wenjia Li Yajun Cui De-an Guo 
supported by the National Key R&D Program of China(Grant Nos.:2018YFC1707900,2019YFC1711000,and 2019YFC1711400);Key-Area Research and Development Program of Guangdong Province(Grant No.:2020B1111110007);the National Natural Science Foundation of China(Grant No.:82003938);Chief Scientist of Qi-Huang Project of National Traditional Chinese Medicine Inheritance and Innovation“One Hundred Million”Talent Project(2020).
Cordyceps sinensis(C.sinensis)is a widely used and highly valuable traditional Chinese medicine.Several dipeptides have been detected in C.sinensis,but current scientific knowledge of its chemical makeup remains limit...
关键词：DIPEPTIDES Cordyceps sinensis Two-dimensional liquid chromatography Identification ISOLEUCINE 
Dipeptides VL increase protein accumulation in C2C12 cells by activating the Akt-mTOR pathway and inhibiting the NF-κB pathway被引量：1
《Food Bioscience》2022年第1期122-130,共9页Mingliang Li Ying Wei Zhiyuan Feng Muyi Cai Yaguang Xu Ruizeng Gu Yongqing Ma Xingchang Pan 
supported by grants from the National Key Research and Development Program of China(No.2016YFD0400604).
The Akt-mTOR signaling pathway plays a central role in regulating intracellular protein metabolism,and the NF-κB signaling pathway plays a vital role in developing skeletal muscle atrophy.In this study,we took the th...
关键词：VL C2C12 Akt-mTOR NF-κB Skeletal muscle 
Inhibition of 3-hydroxy-3-methyl-glutaryl-coenzyme A reductase enzyme by dipeptides identified in dry-cured ham被引量：1
《Food Production, Processing and Nutrition》2021年第1期214-227,共14页Alejro Heres Leticia Mora Fidel Toldrá 
High cholesterolemia is a key risk factor for the development of cardiovascular diseases,which are the main cause of mortality in developed countries.Most therapies are focused on the modulation of its biosynthesis th...
关键词：DIPEPTIDES Dry-cured ham Bioactivity HMG-CoA reductase 
Correction to: Inhibition of 3-hydroxy-3-methyl-glutarylcoenzyme A reductase enzyme by dipeptides identified in drycured ham
《Food Production, Processing and Nutrition》2021年第1期312-313,共2页Alejro Heres Leticia Mora Fidel Toldrá 
Correction to:Food Prod Process Nutr 3,18(2021)https://doi.org/10.1186/s43014-021-00058-w Following the publication of the original article(Heres et al.,2021),the authors identified a typesetting error in Fig.1,and Fi...
关键词：identif deviation error 
Profiling and identification of aqueous extract of Cordyceps sinensis by ultra-high performance liquid chromatography tandem quadrupole-orbitrap mass spectrometry被引量：7
《Chinese Journal of Natural Medicines》2019年第8期631-640,共10页YAO Chang-Liang QIAN Zheng-Ming TIAN Wen-Shuai XU Xiao-Qian YAN Yu SHEN Yao LU Song-Mao LI Wen-Jia GUO De-An 
supported by National Key R&D Program of China(Nos.2018YFC1707900 and 2018YFC1707300)
Characterization of aqueous extract in traditional Chinese medicine(TCM) is challenging due to the poor retention of the analytes on conventional C18 columns. This study presents a systematic characterization method b...
关键词：AQUEOUS extract CORDYCEPS SINENSIS DIPEPTIDES NUCLEOSIDES 
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