Promoting the functional maturation of the desired cell types derived from human pluripotent stem cells (hPSCs) remains a major challenge, especially for hepatocytes, as routine access to metabolically functional he...
This work is supported by grants from the Ministry of Science and Technology National Basic Research Program of China (973 program) (2009CB941001, 2011CBAOIO00, 2011CB944203, 2011 CB965101), the National Science Fund for Distinguished Young Scholars (31025016), the National Natural Science Foundation of China (31071293), Maj or Program of Knowledge Innovation Plan, CAS (KSCX2-YW-R-227) and Science and Technology Planning Project of Guangdong Province, China (2011A060901019).
Embryonic stem (ES) cells are powerful tools for generating genetically modified animals that can assist in advancing our knowledge of mammalian physiology and disease. Pigs provide outstanding models of human genet...
Supported by the National Nature Science Foundation of China (Grant Nos. 30725012,30630039 and 90813033);Knowledge Innovation Project of Chinese Academy of Sciences (Grant No.KSCX2-YW-R-48);National Key Basic Research and Development Program of China (Grant Nos. 2006CB701504,2006CB943600,2007CB948002,2007CB947804.2007CB947900);Guangzhou Science and Technology Development Funds (Grant No.2008A1-E4011)
In 2006,an article published in Cell by Shinya Yamanaka took by surprise the stem cell research community. By performing systematic retroviral transduction of factors enriched in embryonic stem (ES) cells,the authors ...