Advances in cancer treatment allow women to be cured and live longer. However, the necessary chemotherapy and radiotherapy regimens have a negative impact on future fertility. Oncofertility has emerged as a new interd...
Considerable progress has been made in the field of cancer immunotherapy in recent years. This has been made possible in large part by the identification of new immune-based cellular targets and the development of nov...
Erythropoietin-producing hepatoma(EPH) receptors are considered the largest family of receptor tyrosine kinases and play key roles in physiological and pathologic processes in development and disease.EPH receptors are...
supported by Grant R01CA164509 and R21CA134391 from the National Institutes of Health, USA (JFZ), DBI- 0852720 and CHE-1213161 from the National Science Foundation, USA (JFZ)
We developed phase-switch microfluidic devices for molecular profiling of a large number of single cells.Whole genome microarrays and RNA-sequencing are commonly used to determine the expression levels of genes in cel...
RNA interference(RNAi)has become a gold standard for validating gene function in basic life science research and provides a promising therapeutic modality for cancer and other diseases.This minireview focuses on the p...
Targeted therapies include small-molecule inhibitors and monoclonal antibodies, have made treatment more tumor-specific and less toxic, and have opened new possibilities for tailoring cancer treatment. Nevertheless, t...
funded partly by a program grant from the National Health and Medical Research Council of Australia(NH&MRC);supported by Senior Research Fellowships from the NH&MRC;support of the Pfizer Australia Fellowship
The vascular endothelial growth factor (VEGF) family of soluble protein growth factors consists of key mediators of angiogenesis and lymphangiogenesis in the context of tumor biology. The members of the family, VEGF-A...