NEPRILYSIN

作品数：28被引量：69H指数：4
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相关领域：医药卫生更多>>
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相关机构：首都医科大学宣武医院广东医学院天津科技大学深圳市第五人民医院更多>>
相关期刊：《Translational Neurodegeneration》《中风与神经疾病杂志》《海峡药学》《中国生物工程杂志》更多>>
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Role of angiotensin receptor-neprilysin inhibitor in diabetic complications
《World Journal of Diabetes》2024年第5期867-875,共9页Ying Liu Cun-Yu Lu Yi Zheng Yu-Min Zhang Ling-Ling Qian Ku-Lin Li Gary Tse Ru-Xing Wang Tong Liu 
Supported by Tianjin Key Medical Discipline(Specialty)Construction Project,No.TJYXZDXK-029A;the National Natural Science Foundation of China,No.82370342.
Diabetes mellitus is a prevalent disorder with multi-system manifestations,causing a significant burden in terms of disability and deaths globally.Angio-tensin receptor-neprilysin inhibitor(ARNI)belongs to a class of ...
关键词：Angiotensin receptor-neprilysin inhibitor Diabetic mellitus COMPLICATION 
Effect of Angiotensin Receptor-neprilysin Inhibitor on Acute Kidney Injury in Patients With Acute Decompensated Heart Failure
《Cardiology Discovery》2024年第1期23-29,共7页Gonghao Li Yanli Zhao Zhongxing Peng Kun Liu Delu Yin Yunfeng Zhao 
supported by the First People’s Hospital of Lianyungang Talent Fund(QN202003);the Research and Development Fund of Kangda College of Nanjing Medical University(KD2022KYJJZD068).
Objective:The risk of acute kidney injury(AKI)is high in patients with acute decompensated heart failure(ADHF).The aim of this study is to analyze the role of urinary neutrophil gelatinase-associated lipocalin(uNGAL)i...
关键词：Acute kidney injury Acute decompensated heart failure Angiotensin receptor-neprilysin inhibitor Angiotensin-converting enzyme inhibitor Sacubitril valsartan BENAZEPRIL 
Efficacy and safety of oral Chinese patent medicine combined with sacubitril/valsartan in the treatment of chronic heart failure:A Metaanalysis
《Journal of Hainan Medical University》2023年第16期52-60,共9页TAO Shi-yi TANG Xian-wen ZHANG Lan-xin YU Lin-tong ZHANG Jin YANG Deshuang LI Ling-ling HUANG Li WU Jia-yun 
National Natural Science Foundation of China (No.81803925);National Key Research and Development Program (No.2017YFC1700102)。
Objective:To systematically evaluate the clinical efficacy of oral Chinese patent medicine combined with sacubitril/valsartan in treating chronic heart failure(CHF).Methods:CNKI,CSPD,CCD,CBM,PubMed,Web of Science,Coch...
关键词：Oral Chinese patent medicine Sacubitril/valsartan Angiotensin receptor-neprilysin inhibitor Chronic heart failure Qili Qiangxin Capsule Qishen Yiqi Pill Dengzhan Shengmai Capsule 
Emerging Treatment Approaches to Improve Outcomes in Patients with Heart Failure被引量：1
《Cardiology Discovery》2022年第4期231-240,共10页Barry H.Greenberg 
Heart failure(HF)is a major public health problem around the world.Although currently available therapies have improved outcomes,morbidity and mortality in patients with HF remain unacceptably high.Most guideline-reco...
关键词：Heart failure Left ventricular ejection fraction:Angiotensin receptor neprilysin inhibitor Sodium glucose cotransporter 2 Vericiguat Omecamtiv mecarbil 
Intranasal neprilysin rapidly eliminates amyloid-beta plaques, but causes plaque compensations: the explanation why the amyloid-beta cascade may fail?被引量：2
《Neural Regeneration Research》2022年第9期1881-1884,共4页Christian Humpel 
Neurodegenerative brain disorders are a major burden in our society,such as Alzheimer´s disease.In order to repair or prevent such diseases,drugs are designed which enter the brain,but the blood-brain barrier limits ...
关键词：AMYLOID-BETA amyloid-beta degrading enzyme clear plaque collagen biomaterial INTRANASAL NEPRILYSIN nose-to-brain 
Clinical efficacy of angiotensin-receptor neprilysin inhibitors in the treatment of maintenance hemodialysis with heart failure
《China Medical Abstracts(Internal Medicine)》2022年第2期114-115,共2页SUN Changli 
Objective To observe the clinical efficacy of angiotensin-receptor neprilysin inhibitors (ARNI) in the treatment of maintenance hemodialysis (MHD) with heart failure.Methods The clinical data of heart failure patients...
关键词：clinical HEMODIALYSIS TREATMENT 
Angiotensin receptor blocker neprilysin inhibitors被引量：3
《World Journal of Cardiology》2021年第8期325-339,共15页Daisuke Usuda Toshihiro Higashikawa Yuta Hotchi Kenki Usami Shintaro Shimozawa Shungo Tokunaga Ippei Osugi Risa Katou Sakurako Ito Toshihiko Yoshizawa Suguru Asako Kentaro Mishima Akihiko Kondo Keiko Mizuno Hiroki Takami Takayuki Komatsu Jiro Oba Tomohisa Nomura Manabu Sugita 
Heart failure(HF)is a clinical syndrome that results from a structural or functional cardiac disorder that reduces the ability of the ventricle of the heart to fill with,or eject,blood.It is a multifaceted clinical co...
关键词：Angiotensin receptor blocker and neprilysin inhibitor Chronic heart failure Renin-angiotensin-aldosterone-system Sympathetic nervous system Natriuretic peptide Sacubitril/valsartan 
Effect of angiotensin receptor neprilysin inhibitor on ventricular remodeling after myocardial infarction in rats
《Journal of Hainan Medical University》2020年第22期1-5,共5页Ye Du Jian An Yan-Qing Guo Qing-Bo Bao Xiao-Hong Li 
The application of basic research project of Shanxi provincial department of science and technology(No.201901D111445)
Objective:To investigate the effect of Angiotensin Receptor Neprilysin Inhibitor(ARNI)on ventricular remodeling after AMI in rats.Methods:Sixty male SD rats were randomly divided into Control group,AMI group,AMI-valsa...
关键词：Acute myocardial infarction Angiotensin Receptor Neprilysin Inhibitor Ventricular remodeling 
Effect of Angiotensin Receptor-Neprilysin Inhibitor versus Valsartan on Cardiac Status in Patients with Chronic Heart Failure with Reduced Ejection Fraction: A Randomized Clinical Trial in Rangpur Medical College Hospital, Bangladesh被引量：1
《Open Journal of Internal Medicine》2020年第1期21-34,共14页Shakil Ghafur Abu Zahid Haripada Sarkar Rabindra Nath Barman Abdullah Al-Mahmud Mahbubur Rahman Hasanul Islam 
Background: Heart failure with reduced ejection fraction has a significant association with considerable morbidity and mortality, but there is still inadequacy in appropriate treatment to prevent this condition. We ob...
关键词：Chronic Heart Failure Ejection Fraction Angiotensin Receptor-Neprilysin INHIBITOR (ARNi) NT-proBNP 
黑逍遥散对AD模型小鼠海马区Aβ_(1-42),GSK-3β,NEP,IDE表达的影响被引量：17
《中国实验方剂学杂志》2019年第5期36-42,共7页吴红彦 马春林 崔淑梅 朱凯敏 刘佳楠 曾庆涛 
国家自然科学基金地区基金项目(81660760);兰州市2015年人才创新创业扶持项目(2015-RC-24)
目的:研究黑逍遥散对阿尔茨海默症(Alzheimer disease,AD)小鼠海马区β淀粉样多肽1-42(β-amyloid 1-42peptide,Aβ1-42),糖原合成酶激酶-3(glycogen synthase kinase-3β,GSK-3β),脑啡肽酶(neprilysin,NEP),胰岛素抵抗酶(insulindegra...
关键词：阿尔茨海默病 黑逍遥散 β淀粉样多肽1-42(β-amyloid 1-42 peptide Aβ1-42) 糖原合成酶激酶-3(glycogen synthase kinase-3β GSK-3β) 脑啡肽酶(neprilysin NEP) 胰岛素抵抗酶(insulin-degrading enzyme IDE) 
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