supported by the National Natural Science Foundation of China(82074036).
Objective:To explore the neuroprotective effects of the Shaoyao Gancao decoction(SGD)against excitatory damage in PC12 cells and the role of the Src-NR2-nNOS pathway mediation by SGD in regulatingγ-aminobutyric acid(...
The work was supported by the National Natural Science Foundation of China(82204200);the International Postdoctoral Exchange Fellowship Program(Talent-Introduction Program,YJ20210279,China);the China Postdoctoral Science Foundation(2022M711939);to Fabao Zhao,and the Natural Science Foundation of Shandong Province(ZR2022QH287 to Fabao Zhao and ZR2022QH312 to Na Liu,China).
The N-methyl-d-aspartate(NMDA)receptors,which belong to the ionotropic Glutamate receptors,constitute a family of ligand-gated ion channels.Within the various subtypes of NMDA receptors,the GluN1/2A subtype plays a si...