NMDAR

作品数：267被引量：761H指数：12
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相关机构：中南大学中国医科大学福建医科大学南京医科大学更多>>
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Mechanosensitivity of N-methyl-D-aspartate receptors(NMDAR)is the key through which amyloid beta oligomers activate them被引量：2
《Neural Regeneration Research》2022年第6期1263-1264,共2页Giulia Fani Fabrizio Chiti 
Regione Toscana(FAS-Salute 2014;Project Supremal and FAS-Salute 2018;Project PRAMA)(to FC).
Alzheimer’s disease(AD)is one of the major forms of dementia,accounting for 60 to 80%of the cases of dementia,affecting approximately 50 million people worldwide,which is why it has become an object of great interest...
关键词：AMYLOID Alzheimer Aβ 
State-of-art modelling of inflammatory astrocyte-synapse interactions in injury and amyotrophic lateral sclerosis被引量：1
《Neural Regeneration Research》2017年第1期75-76,共2页András Lakatos 
Different outcomes of astrocyte inflammatory signalling in injury and neurodegeneration：It is emerging that astrocytes have a significant impact on the neuronal network by modulating synaptic connections and neuronal...
关键词：astrocyte amyotrophic neuronal synaptic modulating insight viability glutamate inflammation NMDAR 
Targeting neuronal nitric oxide synthase as a valuable strategy for the therapy of neurological disorders被引量：3
《Neural Regeneration Research》2016年第11期1731-1734,共4页Cristina Maccallini Rosa Amoroso 
The management of neurological disorders have huge and increasing human and economic costs. Despite this, there is a scarcity of effective therapeutics, and there is an extreme urgency for new and real treatments. In ...
关键词：AMIDINES carbonic anhydrase INHIBITORS neurological diseases neuronal nitric oxide synthase NMDAR PSD95 
Molecular mechanisms of NMDA receptor-mediated excitotoxicity:implications for neuroprotective therapeutics for stroke被引量：5
《Neural Regeneration Research》2016年第11期1752-1753,共2页Victor Li Yu Tian Wang 
Excitotoxicity is a process observed in many disease states by which an excessive synaptic excitation causes neuronal death, and is thought to be triggered by the extracellular accumulation of the excitatory neurotran...
关键词：NMDAR Molecular mechanisms of NMDA receptor-mediated excitotoxicity 
Beyond reproduction：the role of progesterone in neuropathic pain after spinal cord injury被引量：1
《Neural Regeneration Research》2016年第8期1238-1240,共3页Susana Laura González María Florencia Coronel 
partly supported by grants from CONICET(PIP201-101-00576);Fundación RenéBarón
Neuropathic pain,a type of pain arising after direct damage or disease of the nervous system,is often intractable and challenges the search of effective therapeutic strategies.In particular,neuropathic pain is a very ...
关键词：progesterone intractable Beyond contributor reproduction neuronal NMDAR glial synaptic targeting 
Fractalkine: multiple strategies to counteract glutamate receptors activation leading to neuroprotection被引量：2
《Neural Regeneration Research》2015年第8期1214-1215,共2页Clotilde Lauro 
Glutamate（Glu）is the main excitatory amino acid in the brain and plays a pivotal role in many neurophysiological functions.Nevertheless,an excess and prolonged exposure to Glu determines the overactivation of glutam...
关键词：glutamate excitatory impairment homeostasis neuronal Glutamate NMDAR intracellular adenosine microglia 
GluN2B-NMDA receptors in Alzheimer's disease:beyond synapse loss and cell death被引量：1
《Neural Regeneration Research》2014年第21期1878-1879,共2页Qiang Zhou 
Alzheimer＇s disease （AD） is one of the most devastating dis- eases affecting the life and health of aging population. Two hallmarks of AD are senile plaques and neurofibrillary tan- gles, and AD is well known for t...
关键词：GluN2B-NMDA receptors in Alzheimer’s disease NMDA NMDAR 
Controlling N-methyl-D-aspartate receptor subunit 1 with calcitonin gene related peptide after cerebral ischemic injury
《Neural Regeneration Research》2006年第7期585-588,共4页Jixiang Cui1, Peng Qu2, Chunping Qiao3 1Department of Clinical Laboratory, Fourth Affiliated Hospital of China Medical University, Shenyang 110032, Liaoning Province, China 2Department of Neurobiology, Basic Medical College of China Medical University, Shenyang 110032, Liaoning Province, China 3Department of Emergency, Baicheng Central Hospital of Jilin Province, Baicheng 137000, Jilin Province, China 
BACKGROUND: Activation of N-methyl-D-aspartate receptor (NMDAR) is a key link of exitotoxicity at the phase of cerebral ischemic injury. Because NMDAR is a main way to mediate internal flow of Ca2+ among glutamic acid...
关键词：NMDAR MRNA Controlling N-methyl-D-aspartate receptor subunit 1 with calcitonin gene related peptide after cerebral ischemic injury GENE 
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