Supported by Henan Provincial Science and Technology Research Project,No.242102310203.
BACKGROUND The use of network pharmacology and blood metabolomics to study the patho-genesis of violent aggression in patients with schizophrenia and the related drug mechanisms of action provides new directions for r...
supported by the Chongqing Basic Research and Frontier Exploration Project(cstc2022ycjh-bgzxm0119).
Olanzapine(OLZ)is a widely prescribed antipsychotic drug with a relatively ideal effect in the treatment of schizophrenia(SCZ).However,its severe metabolic side effects often deteriorate clinical therapeutic complianc...
the Natural Science Foundation of Hubei Province(No.2021CFB301 and No.2021CFB299);the State Key Laboratory of Advanced Technology for Materials Synthesis and Processing(WUT)(No.2022-KF-27).
Objective Numerous schizophrenic patients are suffering from obesity primarily attributed to antipsychotic medication and poor dietary habits.This study investigated the progressive deterioration of olanzapine-induced...
Schizophrenia is a prevalent and disabling disorder, commonly treated with medications such as clozapine and olanzapine. However, long-term side effects and limitations of these drugs, coupled with treatment resistanc...
BACKGROUND Treatment-refractory schizophrenia(TRS),accounting for approximately 30%of all schizophrenia cases,has poor treatment response and prognosis despite treatment with antipsychotic drugs.AIM To analyze the the...
Objective: To observe the clinical study of Jieyu Anshen Decoction combined with olanzapine in the treatment of insomnia patients with bad mood and sleep disorders. Methods: In this study, 112 insomnia patients from O...
Objective: to study and explore the effect of tandospirone+olanzapine on schizophrenia. Methods: in this study, 80 hospitalized patients with PANSS scores higher than 60 at admission from October 2018 to October 2019 ...
Objective To observe the efficacy and safety of the combination of agomelatine and low-dose olanzapine(AO)in the treatment of postprandial distress syndrome(PDS)with depression,anxiety and sleep disorders.Methods From...
SUMMARY A married mother in her 50s acutely developed vomiting,diarrhoea and severe epigastric pain 2 weeks following discharge from an acute psychiatric inpatient unit.She presented to the emergency department compla...
Background:Depression will become the second most common disease after coronary heart disease(CHD).Escitalopram and olanzapine are commonly used to treat depression.Some studies indicated that escitalopram combined wi...