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PARKINSONS: 作品数：206被引量：380H指数：9; 导出分析报告; 相关领域：医药卫生生物学更多>>; 相关作者：王宏梅王奇王奇更多>>; 相关机构：辽东学院安徽医科大学广州中医药大学中山大学更多>>; 相关期刊：更多>>; 相关基金：国家自然科学基金国家重点基础研究发展计划北京市自然科学基金国家高技术研究发展计划更多>>

Pioneering a new era in Parkinson’s disease management through adipose-derived mesenchymal stem cell therapy: 《BIOCELL》2024年第10期1419-1428,共10页MOHAMMAD-SADEGH LOTFI FATEMEH B.RASSOULI; Parkinson’s disease(PD)is one of the fastest-growing neurodegenerative disorders worldwide.So far,PD treatments only offer little clinical relief and cannot reverse or stop the disease progression.Stem cell(SC)therap...; 关键词：Parkinson’s disease Adipose derived-mesenchymal stem cells Cell therapy Dopaminergic neurons

Brain delivery of fibronectin through bioactive phosphorous dendrimers for Parkinson’s disease treatment via cooperative modulation of microglia: 《Bioactive Materials》2024年第8期45-54,共10页Waicong Dai Mengsi Zhan Yue Gao Huxiao Sun Yu Zou Regis Laurent Serge Mignani Jean-Pierre Majoral Mingwu Shen Xiangyang Shi; supported by the National Natural Science Foundation of China(52350710203 and U23A2096);the Science and Technology Commission of Shanghai Municipality(21490711500,23WZ2503300,23520712500 and 20DZ2254900);the National Key R&D Program(2022YFE0196900);the Shanghai Education Commission through the leading talent program.S.M.and X.S.also acknowledge the support by the Fundaçao para a Ciencia e a Tecnologia(FCT)with Portuguese Government funds through the CQM Base Fund-UIDB/00674/2020(DOI:10.54499/UIDB/00674/2020);Programmatic Fund-UIDP/00674/2020(DOI:10.54499/UIDP/00674/2020).; Effective treatment of Parkinson’s disease(PD),a prevalent central neurodegenerative disorder particularly affecting the elderly population,still remains a huge challenge.We present here a novel nanomedicine formulat...; 关键词：Phosphorous dendrimers FIBRONECTIN Parkinson’s disease Blood brain barrier Combination therapy

Developing a Model for Parkinson’s Disease Detection Using Machine Learning Algorithms: 《Computers, Materials & Continua》2024年第6期4945-4962,共18页Naif Al Mudawi; The funding for thisworkwas provided by theResearch Groups Funding Program,Grant Code(NU/GP/SERC/13/30).; Parkinson’s disease(PD)is a chronic neurological condition that progresses over time.People start to have trouble speaking,writing,walking,or performing other basic skills as dopamine-generating neurons in some brain...; 关键词：Light GBM cross-validation ROC-AUC Parkinson’s disease(PD) SVM and XGBoost

Focusing on the tetra-partite synapse in Parkinson’s disease research using human patient-derived neurons: 《Neural Regeneration Research》2024年第5期979-981,共3页Diogo Cordeiro Tchelet Stern Shani Stern; supported by the Israel Science Foundation(ISF grant 1994/21 and 3252/21);Zuckerman(Zuckerman STEM leadership program)(to SS).; Parkinson’s disease(PD)was first described as a neurological disease by Dr.James Parkinson in 1817 as a“shaking palsy”.Since that time,much more is known about the pathophysiology of PD yet the disease is still unc...; 关键词：patients ALZHEIMER Focus

Binary Hybrid Artificial Hummingbird with Flower Pollination Algorithm for Feature Selection in Parkinson’s Disease Diagnosis被引量：1: 《Journal of Bionic Engineering》2024年第2期1003-1021,共19页Liuyan Feng Yongquan Zhou Qifang Luo; supported by the National Natural Science Foundation of China under Grant Nos.U21A20464,62066005;the Innovation Project of Guangxi Graduate Education under Grant No.YCSW2023259.; Parkinson’s disease is a neurodegenerative disorder that inflicts irreversible damage on humans.Some experimental data regarding Parkinson’s patients are redundant and irrelevant,posing significant challenges for di...; 关键词：Artificial Hummingbird Algorithm Flower pollination algorithm Feature selection Parkinson’s disease Meta-heuristic

Controversies and insights into PTBP1-related astrocyte-neuron transdifferentiation:neuronal regeneration strategies for Parkinson’s and Alzheimer’s disease: 《Translational Neurodegeneration》2024年第1期184-199,共16页Simon McDowall Vaishali Bagda Stuart Hodgetts Frank Mastaglia Dunhui Li; funded by Bryant Stokes Neurological Research Fund,FightMND Drug Development Grant,and Channel 7 Telethon research grant.; Promising therapeutic strategies are being explored to replace or regenerate the neuronal populations that are lost in patients with neurodegenerative disorders.Several research groups have attempted direct reprogramm...; 关键词：Neuronal regeneration Astrocyte-neuron reprogramming Astrocyte heterogeneity Therapeutic strategies

Translating Pathological Brain Activity Primers in Parkinson’s Disease Research: 《Research》2024年第1期735-752,共18页Daniela Mirzac Svenja L.Kreis Heiko J.Luhmann Gabriel Gonzalez-Escamilla Sergiu Groppa; the German Research Foundation(DFG;SFB-TR-128).; Translational experimental approaches that help us better trace Parkinson’s disease(PD)pathophysiological mechanisms leading to new therapeutic targets are urgently needed.In this article,we review recent experimenta...; 关键词：CLINICAL knowledge INSIGHT

Cath-KP,a novel peptide derived from frog skin,prevents oxidative stress damage in a Parkinson’s disease model: 《Zoological Research》2024年第1期108-124,共17页Huanpeng Lu Jinwei Chai Zijian Xu Jiena Wu Songzhe He Hang Liao Peng Huang Xiaowen Huang Xi Chen Haishan Jiang Shaogang Qu Xueqing Xu; supported by the National Natural Science Foundation of China(31772476 and 31911530077 to X.X.,81870991 and U1603281 to S.Q.);Guangdong Basic and Applied Basic Research Foundation(2023A1515010914 to X.X.);Natural Science Foundation of Guangdong Province(2022A1515010352 to S.Q.)。; Parkinson’s disease(PD)is a neurodegenerative condition that results in dyskinesia,with oxidative stress playing a pivotal role in its progression.Antioxidant peptides may thus present therapeutic potential for PD.In...; 关键词：Cath-KP PEPTIDE Parkinson’s disease Oxidative stress Neuroprotection

Precision Gene Therapy Reverses Parkinson’s Symptoms in Monkeys: 《Bulletin of the Chinese Academy of Sciences》2023年第4期217-219,共3页YAN Fusheng; Can a single shot of gene therapy safely reverse Parkinson’s disease?New study published in Cell shows that it could be feasible in monkeys,providing fresh hope for better treatment options.As reported in Cell on Nov...; 关键词：THERAPY THERAPY feasible

Privacy Preserved Brain Disorder Diagnosis Using Federated Learning: 《Computer Systems Science & Engineering》2023年第11期2187-2200,共14页Ali Altalbe Abdul Rehman Javed; supported by the Deanship of Scientific Research at Prince Sattam bin Aziz University under the Research Project (PSAU/2023/01/22425).; Federated learning has recently attracted significant attention as a cutting-edge technology that enables Artificial Intelligence(AI)algorithms to utilize global learning across the data of numerous individuals while ...; 关键词：Privacy preservation brain disorder detection Parkinson’s disease diagnosis federated learning healthcare machine learning

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