supported by the National Natural Science Foundation of China(82073001 and 82103423);Shanghai Natural Science Foundation(23ZR1454800);Scientific Research Foundation for the Introduction of Talent in Shanghai Stomatological Hospital(SSDC-2021-RC01).
Carcinoma-associated fibroblasts(CAFs)are the main cellular components of the tumor microenvironment and promote cancer progression by modifying the extracellular matrix(ECM).The tumor-associated ECM is characterized ...
supported by the National Natural Science Foundation of China[82001020 and 81771047];research funding from West China School/Hospital of Stomatology,Sichuan University[RCDWJS2021-13];China Postdoctoral Science Foundation[2019M663525];the Science and Technology Project of Sichuan Province[2021YFG0238].
Mechanical stiffness is recognized as a key physical factor and directs cell function via a mechanotransduction process,from extracellular physical cues to intracellular signaling cascades that affect transcriptional ...
This study was supported by grants from the Chinese National Natural Sciences Foundation(81773099,81630092 and 82130106);Department of Science and Technology of Jiangsu Province(BK20192005);the program B for Outstanding PhD candidate of Nanjng University(202001B051).
Hydrogen sulfide(H2S)is widely recognized as the third endogenous gas signaling molecule and may play a key role in cancer biological processes.ADT-OH(5-(4-hydroxyphenyl)−3H-1,2-dithiocyclopentene-3-thione)is one of t...
supported by the Japanese Society for the Promotion of Science(JSPS)postdoctoral research fellowship for foreign researcher grant(P 12380);JSPS KAKENHI Grant Number 24•02380;Marie Curie Individual Fellowship grant(BEND,H2020-MSCA-IF-2015,704807 and EPSRC Engineering Fellowship for Growth-PRINTSKIN(EP/M002527/1)).
Scaffold engineering has attracted significant attention for three-dimensional(3D)growth,prolifer-ation and differentiation of stem cells in vitro.Currently available scaffolds suffer from issues such as poor ability ...
supported by grants from Key Project of Tianjin Natural Science Foundation (Grant No.18JCZDJC35200);NSFC-FRQS program (Grant No.81661128009);The Science & Technology Development Fund of Tianjin Education Commission for Higher Education (Grant No.2017KJ202);Scientific Research Foundation for Returned Scholars and Doctoral Program of Tianjin Medical University Cancer Institute and Hospital (Grant No.B1703)
Objective: To explore the effect of cytosolic phospholipase A2α(cPLA2α) on hepatocellular carcinoma(HCC) cell adhesion and the underlying mechanisms.Methods: Cell adhesion, detachment, and hanging-drop assays were u...