云南高校图书馆联盟文献共享服务平台- PEPTIDE

PEPTIDE: 作品数：1062被引量：2043H指数：15; 导出分析报告; 相关领域：医药卫生更多>>; 相关作者：杨松成张学敏张滨魏开华王红霞更多>>; 相关机构：北京大学福建医科大学复旦大学军事医学科学院更多>>; 相关期刊：更多>>; 相关基金：国家自然科学基金国家重点基础研究发展计划中国博士后科学基金国家高技术研究发展计划更多>>

In vivo self-assembled bispecific fluorescence probe for early detection of bladder cancer and metastasis: 《Science Bulletin》2025年第3期407-418,共12页Da-Yong Hou Ni-Yuan Zhang Peng Zhang Xiang-Peng Li Jiong-Cheng Wu Mei-Yu Lv Zhi-Jia Wang Xing-Jie Hu Jian-Xiao Liang Hong-Lei Wang Yue-Ze Wang Hui-Hui You Hong-Wei An Hao Wang Wanhai Xu; supported by the National Key R&D Program of China(2022YFA1205701 and 2020YFA0210800);the National Natural Science Foundation of China(52322308,51725302,52273126,11621505,and 82302266);Beijing Nova Program(20230484237);the Strategic Priority Research Program of the Chinese Academy of Sciences(XDB36000000);the Key Research and Development Program of Heilongjiang Province(2022zX06004);Hong Kong scholar project(Xj2024052);Harbin Medical University Cancer Hospital Haiyan Foundation(JYQ2024-03 and JZD2024-17);the Nn10 program of Harbin Medical University Cancer Hospital(Nn102024-01);the Climing program of Harbin Medical University Cancer Hospital(PDYS2024-03);China Postdoctoral Science Foundation(2024MD753933);Heilongjiang Postdoctoral Fund(LBH-Z23221).; Tumor metastasis accounts for over 90%of tumor-related deaths,prompting the development of fluorescently labeled tumor-specific molecular imaging agents for differentiating tumors from normal tissues.However,early det...; 关键词：Self-assembly PEPTIDE NANOMATERIAL Fluorescence imaging Bladder cancer

Chiral polypeptide nanoparticles as nanoadjuvants of nanovaccines for efficient cancer prevention and therapy被引量：3: 《Science Bulletin》2023年第3期284-294,M0004,共12页Yuanzhen Su Weiguo Xu Qi Wei Yang Ma Jianxun Ding Xuesi Chen; supported by the National Key Research and Development Program(2022YFC2603500,2022YFC2603501,2021YFC2400600,2021YFC2400603,and 2021YFC2400604);the National Natural Science Foundation of China(52273158,52273159,U21A2099,52022095,and 52073280);the Science and Technology Development Program of Jilin Province(20210509005RQ,20210504001GH,20200404182YY,and 20200201322JC);the Special Project for City-Academy Scientific and Technological Innovation Cooperation of Changchun(21SH14);the Youth Innovation Promotion Association of Chinese Academy of Sciences(2019230).; The chirality of bioactive molecules is closely related to their functions.D-amino acids commonly distributed in the bacterial cell walls trigger a robust anti-infective immune response.Inspired by that,two kinds of c...; 关键词：Chiral polypeptide Nanoadjuvant NANOVACCINE Immunoactivation Cancer prevention and treatment

What took you so long?Peptide-receptor kinase signaling mediates reproductive isolation in plants: 《Science Bulletin》2019年第19期1390-1392,共3页Yu-Jie Li Jia-Qi Pei Wei-Hua Tang; supported by the National Natural Science Foundation of China(31570318); The peptide-receptor kinase-based intercellular signaling becomes an important molecular base for various aspects of plant life activities[1],particularly exemplified in the extensive molecular interactions in the jou...; 关键词：SO LONG Peptide-receptor in PLANTS

Targeted peptide-Au cluster binds to epidermal growth factor receptor (EGFR) in both active and inactive states： a clue for cancer inhibition through dual pathways被引量：4: 《Science Bulletin》2018年第6期349-355,共7页Peng Zhang Jiao Zhai Xueyun Gao Hongkang Zhao Wenyong Su Lina Zhao; supported by the National Natural Science Foundation of China(31571026,11404333);the Special Program for Applied Research on Super Computation of the NSFC-Guangdong Joint Fund(the second phase)under Grant No.U1501501; The epidermal growth factor receptor （EGFR） has become an important target protein in anticancer drug development. Meanwhile, peptide-Au cluster has been proposed as potential targeted nano-drug assembled by targeti...; 关键词：peptide-Au cluster EGFR Targeted binding Anticancer

A peptide-based near-infrared fluorescence probe for dynamic monitoring senile plaques in Alzheimer＇s disease mouse model被引量：1: 《Science Bulletin》2017年第23期1593-1601,共9页Chen-Wei Wang Dou-Dou Nan Xin-Meng Wang zun-Ji Ke Guo-Jun Chen Jiang-Ning Zhou; supported by the National Key Research and Development Program of China (2016YFC1305900);the Strategic Priority Research Program of the Chinese Academy of Sciences (XDB02030001);the National Natural Science Foundation of China (91132304, 91432305); In vivo monitoring neuropathological changes in Alzheimer＇s disease （AD） animal model is critical for drug development. Here, by integrating blood-brain barrier penetrable peptide, we have developed a peptide probe...; 关键词：Alzlaelmer＇s diseaseSenile plaquesAmyloid-β LRP-1 Angiopep In vivo imaging AD animal model

The reactive activities of natural amino acids: key principles of peptide-templated Au cluster synthesis被引量：1: 《Science Bulletin》2016年第22期1732-1738,共7页Xu Li Nan Li Lina Zhao; supported by the National Key Basic Research Program of China (2013CB932703, 2013CB933704);the National Natural Science Foundation of China (11404333, 31571026);the Special Program for Applied Research on Super Computation of the NSFC-Guangdong Joint Fund (the second phase); Coating of gold nanoclusters with peptides is an important targeting method in biomedical applications.However, their synthetic method highly influences their targeting ability. Current methods often use harsh reagent...; 关键词：Reactive activity Amino acid Synthesis in situ Au nanocluster DFT calculation

A label-free colorimetric assay for detection of c-Myc mRNA based on peptide nucleic acid and silver nanoparticles被引量：6: 《Science Bulletin》2016年第4期276-281,共6页Xia Li Juan Song Bao-Li Chen Bing Wang Rui Li Hui-Min Jiang Ji-Feng Liu Chen-Zhong Li; the National Natural Science Foundation of China (21305058, 21205056, 21075058 and 21503104);Tai-Shan Scholar Research Fund of Shandong Province; A label-free colorimetric protocol based on peptide nucleic acid/silver nanoparticles(PNA/Ag NPs) has been initially proposed for specific recognition of m RNA.Making use of the controlled silver nanoparticles aggrega...; 关键词：Colorimetric · c-Myc mRNA · Peptidenucleic acid · Silver nanoparticles

A novel method for thermodynamic study on binding of copper ion with Alzheimer’s amyliod β peptide被引量：1: 《Chinese Science Bulletin》2009年第6期1037-1042,共6页BEHBEHANI G. Rezaei; Supported by the University of Imam Khomeini (Qazvin)and University of Tehran and Iranian National Science Foundation (INSF); The interaction of Cu2+ with the first 16 residues of the Alzheimer's amyliod β peptide, Aβ (1-16), was studied by employing isothermal titration calorimetry at pH 7.2 and 37℃ in aqueous solution. The Gholamreza Re...; 关键词：阿尔茨海默氏症铜离子热力学等温滴定量热法相互作用肽结合位点摩尔焓

Breast cancer-specific serum peptide profiles被引量：4: 《Chinese Science Bulletin》2009年第3期421-429,共9页WANG Na WEN XinYu WANG Jie LI AiLing LI WeiHua LI Tao Li Yan ZHANG XueMin WANG HongXia YANG SongCheng ZHOU Tao GONG WeiLi TIAN YaPing HE Kun; Supported by National Natural Science Foundation of China (Grant No. 30321003);National Key Basic Research and Development Program of China (Grant No. 2004CB518800); Early detection of breast cancer is paramount to successful clinical therapy. Yet, early-stage breast cancer lacks specific symptoms or biomarkers. With the emerging of the mass spectrometric (MS) -based signatures as...; 关键词：乳腺癌光谱测定法血浆肽生物标记

A novel peptide, selected from phage display library of random peptides, can efficiently target into human breast cancer cell被引量：12: 《Chinese Science Bulletin》2008年第6期860-867,共8页DONG Jian LIU WeiQing ZHANG KeJian JIANG AiMei CHEN MingQing; the National Natural Science Foundation of China (Grant No. 30460142); To develop a targeting vector for breast cancer biotherapy, MDA-MB-231 cell, a human breast cancer cell line, was co-cultured with pC89 (9 aa) phage display library of random peptides. In multiple inde- pendent peptid...; 关键词：乳腺癌癌细胞抗菌素缩氨酸

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