supported by the National Natural Science Foundation of China(82274313);Key R&D Program of Shaanxi Province(2023GHZD43);the National Natural Science Foundation of China(81870284).
Background:Formononetin(FMN)has beneficial effects in cardiovascular diseases but its functions and mechanisms in heart failure with preserved ejection fraction(HFpEF)remain unclear.This study aimed at determining whe...
supported by the National Natural Science Foundation of China (82360716,82070422,and 82200330);China Postdoctoral Science Foundation (2023T160526 and 2022M722571);Research Plan Project of Shaanxi Institute of Basic Science (22JHQ053);High-end Foreign Expert Introduction Program of National Science and Technology (G2022040014L);Qinchuangyuan Traditional Chinese Medicine Innovation Research and Development Transformation Project (2022-QCYZH-036).
Peroxisome proliferator-activated receptor gamma coactivator-1(PGC-1)family(PGC-1s),consisting of three members encompassing PGC-1a,PGC-1β,and PGC-1-related coactivator(PRC),was discovered more than a quarter-century...