云南高校图书馆联盟文献共享服务平台- FORMONONETIN

FORMONONETIN: 作品数：11被引量：34H指数：4; 导出分析报告; 相关领域：医药卫生更多>>; 相关作者：杨倩陈刚曹鹏蔡雪婷杨洋更多>>; 相关机构：湖南师范大学南京中医药大学南京师范大学江苏省中医药研究院更多>>; 相关期刊：《生物化学与生物物理进展》《Medicinal Plant》《Acta Pharmacologica Sinica》《细胞与分子免疫学杂志》更多>>; 相关基金：国家自然科学基金更多>>

Formononetin Enhances Autophagy Flux in The Penumbra of Cerebral Ischemia and Improves Nerve Damage: 《生物化学与生物物理进展》2024年第12期3253-3265,共13页GUO Tao ZUO Han-Jun SHI Jin-Sha SHI Hao-Long WANG Zhao CHEN Bo-Lin Li Juan-Juan; 国家自然科学基金(31960194,32460218);昆明医科大学博士研究生创新基金(J114150330296);昆明医科大学大学生创新训练计划(2024CYD038,2024CYD161);昆明理工大学课外学术科技创新基金(2024KJ124,2024ZK134)资助项目。; Objective Formononetin(FOR),a traditional Chinese medicine,has been widely used for nerve protection and nerve function rehabilitation after cerebral stroke.However,the role of FOR in autophagic lysosome function in c...; 关键词：cerebral ischemia formononetin(FOR) autophagy flux PENUMBRA NEUROPROTECTION

Formononetin improves heart failure with preserved ejection fraction in mice by activating the PPARα/PGC-1 pathway: 《Traditional Medicine Research》2024年第4期12-19,共8页Hang Xu Xiaoqian Zhang Liming Huang Fei Li Yiyuan Tian Chao Guo Yi Ding Jing Ma Chao Liu; supported by the National Natural Science Foundation of China(82274313);Key R&D Program of Shaanxi Province(2023GHZD43);the National Natural Science Foundation of China(81870284).; Background:Formononetin(FMN)has beneficial effects in cardiovascular diseases but its functions and mechanisms in heart failure with preserved ejection fraction(HFpEF)remain unclear.This study aimed at determining whe...; 关键词：FORMONONETIN heart failure with preserved ejection fraction PPARΑ PPARα/PGC-1 pathway energy metabolism

Pharmacological Action and Molecular Mechanism of Formononetin: 《Asian Agricultural Research》2023年第11期35-37,41,共4页Xichun HUANG Wenshuang HOU Quan QUAN Jingchao WANG Mingxinzhi WANG Xinyu LIU Chenghao JIN; Supported by Central Government Supports Local College Reform and Development Fund Talent Training Projects(2020GSP16);Undergraduate Innovation and Entrepreneurship Training Program of Heilongjiang Province(202310223122).; Formononetin is an isoflavone phytoestrogen mainly existing in leguminous plants such as Trifolium pretense,Spatholobus suberectus,etc.Studies have proved that formononetin has good anti-inflammatory,antitumor,antioxi...; 关键词：FORMONONETIN ANTI-INFLAMMATORY ANTITUMOR Antioxidant ANTIDEPRESSANT ANXIOLYTIC

Nanostructured lipid carrier as a strategy for encapsulation of formononetin and perilla seed oil:In vitro characterization and stability studies: 《Food Bioscience》2023年第3期2340-2350,共11页Lijun Zheng Hongjia Xu Hanxin Zhang Caihong Shi Wei Zhou Xiangrong Zhang; supported by Livelihood Plan Project of Department of Science and Technology of Liaoning Province(2021JH2/10300069,2019-ZD-0845);Department of Education of Liaoning Province(LJKZ0918).; This study aims to characterize formononetin(FMN)and perilla seed oil(PSO)co-loaded nanostructured lipid carriers(NLC).FMN-PSO-NLC was prepared by melt-emulsification ultrasonic method.The average particle size of FMN...; 关键词：Nanostructured lipid carrier FORMONONETIN Perilla seed oil Antioxidant activity In vitro gastrointestinal Digestion

Formononetin alleviates diabetic cardiomyopathy by inhibiting oxidative stress and upregulating SIRT1 in rats被引量：6: 《Asian Pacific Journal of Tropical Biomedicine》2020年第6期254-262,共9页Manisha J.Oza Yogesh A.Kulkarni; Objective:To evaluate the effect of formononetin on type 2 diabetic cardiomyopathy.Methods:Diabetes was induced by feeding high-fat diet for 2 weeks and administration of 35 mg/kg of streptozotocin in rats.Formononeti...; 关键词：CARDIOMYOPATHY FORMONONETIN Type 2 diabetes SIRT1 CREATININE KINASE Cardiac HYPERTROPHY

刺芒柄花素通过促进解偶联蛋白1(UCP1)表达刺激棕色脂肪细胞产热被引量：5: 《细胞与分子免疫学杂志》2020年第3期242-247,共6页陶金陶磊黄文华; 宁夏医科大学校级课题(XM2018104)。; 目的探讨刺芒柄花素(formononetin)通过解偶联蛋白1(UCP1)调控棕色脂肪细胞产热的机制。方法分离来源于C57BL/6J小鼠的脂肪组织的前体细胞,体外诱导为成熟的棕色脂肪细胞,利用实时定量PCR检测脂肪细胞标志基因脂肪酸结合蛋白4(FABP4)、...; 关键词：刺芒柄花素(formononetin) 棕色脂肪细胞解偶联蛋白1(UCP1) 产热

Content Determination of Flavonoids in Radix Millettiae Speciosae from Different Areas of Guangxi被引量：1: 《Medicinal Plant》2019年第1期31-33,共3页Jingwen GU Liuping WANG Dongping TU Xiajun ZHONG; Supported by Special Project of Guangxi Education Department for the Construction of Advantageous Subjects of Traditional Chinese Medicine(ZYX2015006); [Objectives] This study aimed to investigate the quality of Radix Millettiae Speciosae at different planting sites in Guangxi. [Methods] The content of flavonoids in Radix Millettiae Speciosae was determined by HPLC. ...; 关键词：RADIX Millettiae Speciosae FLAVONOIDS FORMONONETIN Maackiain HPLC

Molecular Mechanism of Induction on Apoptosis of Human Esophageal Cancer HCE-4 Cells by Active Components from Astragalus membranaceus被引量：2: 《Medicinal Plant》2018年第1期63-66,共4页Jiaru WANG Yinghua LUO Xianji PIAO Chang LIU Yi ZHANG Hao WANG Jinqian LI Wanting XU Yang LIU Yiqin WU Chenghao JIN; Supported by the Nature Science Foundation of Heilongjiang Province of China(LC2015036);the Program of Cultivation and Support Projects of Heilongjiang Bayi Agricultural University(XA2015-04);the Research Project of Heilongjiang Bayi Agricultural University(XYB2013-24);the Postdoctoral Scientific Research Foundation of Heilongjiang Province of China(LBH-Q13132);the Scientific Research Innovation Program for College Graduates of Heilongjiang Bayi Agricultural University(YJSCX2017-Y72); [Objectives] To investigate the pharmacologic effects of active components from A. membranaceus on human esophageal cancer HCE-4 cells and its apoptosis mechanism. [Methods] The viabilities of HCE-4 cells were measure...; 关键词：Human esophageal cancer HCE-4 cells FORMONONETIN Astragaloside IV Astragalus root extract APOPTOSIS AKT signal path way

Formononetin ameliorates DSS-induced ulcerative colitis in mice through induction of Nrf2 in colons被引量：11: 《Journal of Chinese Pharmaceutical Sciences》2016年第3期178-188,共11页杨倩陈刚杨洋蔡雪婷庞中化胡春萍张双全曹鹏; National Natural Science Foundation of China(Grant No.81274150,81573680 and 81470179); Isoflavone formononetin（FN） is a main active component of red clover（Trifolium pratense L.）, a medicinal plant possessing antitumorigenic and antioxidant properties. In the present study, we aimed to examine the e...; 关键词：NRF2 Ulcerative colitis Isoflavone formononetin Flammatory cytokines Oxidative stress

Vasorelaxant and antihypertensive effects of formononetin through endothelium-dependent and -independent mechanisms被引量：8: 《Acta Pharmacologica Sinica》2011年第8期1009-1018,共10页Tao SUN Rui LIU Yong-xiao CAO; Acknowledgements This study was supported by grant from the National Natural Science Foundation of China （No 30772566）.; Aim： To investigate the mechanisms underlying the vasorelaxant effect of formononetin, an O-methylated isoflavone, in isolated arteries, and its antihypertensive activity in vivo. Methods： Arterial rings of superior...; 关键词：FORMONONETIN arterial rings VASODILATATION voltage-dependent Ca^2＋ channel intracellular Ca^2＋ release nitric oxide spontaneously hypertensive rats blood pressure

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