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PHOSPHATASE: 作品数：255被引量：886H指数：14; 导出分析报告; 相关领域：医药卫生生物学更多>>; 相关作者：储成才司丽珍曹守云于晓王洪梅更多>>; 相关机构：中国科学院遗传与发育生物学研究所山东大学湖北中医药大学安徽中医学院第一附属医院更多>>; 相关期刊：更多>>; 相关基金：国家自然科学基金国家重点基础研究发展计划国家教育部博士点基金瑞士科学基金更多>>

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期刊=Science China（Life Sciences）

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Nuclear miR-665 aggravates heart failure via suppressing phosphatase and tensin homolog transcription被引量：9: 《Science China(Life Sciences)》2020年第5期724-736,共13页Jiahui Fan Xudong Zhang Xiang Nie Huaping Li Shuai Yuan Beibei Dai Jiabing Zhan Zheng Wen Jiangang Jiang Chen Chen Daowen Wang; supported by grant from the National Natural Science Foundation of China(81822002,81630010,81790624,91839302,31771264 and 31800973)。; Although numerous miRNAs have been discovered,their functions in the different subcellular organelles have remained obscure.In this study,we found that miR-665 was enriched in the nucleus of cardiomyocytes,and then in...; 关键词：nucleus miR-665 heart failure phosphatase and tensin homolog

AMP makes native snake muscle fructose-1,6-bisphosphatase to an alkaline enzyme: 《Science China(Life Sciences)》2000年第1期1-7,共7页赵辅昆徐松琴杜立林许根俊; A substance in the crude preparation of NADP+ has been found, which activates snake muscle fructose-1,6-bisphosphatase at pH 9.2 and inhibits the enzyme at pH 7.5. After isolation and extensive characterization, the s...; 关键词：Fructose-1 6-bisphosphatase AMP activation limited PROTEOLYSIS Mg2+ regulation.

The positive and negative control actions of PTPase on IL-2 signaling: 《Science China(Life Sciences)》1999年第6期614-620,共7页朱锦芳季红斌鲁林荣郭丽英郑仲承刘新垣; The tyrosine phosphorylation of intracellular proteins was greatly increased after the treatment of cells with sodium n-vanadate, the inhibitor of protein tyrosine phosphatase (PTPase) . It was found by using EMSA tha...; 关键词：protein TYROSINE PHOSPHATASE signal TRANSDUCTION INTERLEUKIN-2 sodium n-vanadate.

Conformation of 60-residue peptide fragment from N-terminal of porcine kidney fructose 1,6-bisphosphatase被引量：1: 《Science China(Life Sciences)》1997年第3期251-256,共6页杨伟文赵辅昆许根俊; Project supported in part by the National Natural Science Foundation of China and the Climbing Project of the State Science and Technology Commission of China.; Limited digestion of fructose 1,6-bisphosphatase with subtilisin produces an S-peptide with an about 60-residue peptide fragment that is non-covalently associated with the enzyme. The 60-residue peptide fragment con-s...; 关键词：FRUCTOSE 1 6-bisphosphatase ALLOSTERIC site secondary structure the folding of newly synthesized PEPTIDE conformation adjustment.

Preparation of monoclonal antibodies against chicken liver 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase and their effects on enzyme activities: 《Science China(Life Sciences)》1996年第4期342-349,共8页李同元丁建芳李林许根俊; Project supported by Climbing Project of the State Science and Technology Commission of China and the National Natural Science Foundation of China.; The effects of the monoclonal antibodies (McAbs) directed against chicken liver 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase (6PF-2-K/Fru-2, 6-P2ase) on the structure and function of the enzyme were studied. U...; 关键词：6-phosphofructo-2-kinase/fructose-2 6-bisphosphatase fructose 2 6-bisphosphatase domain MONOCLONAL antibody.

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