云南高校图书馆联盟文献共享服务平台- PRAVASTATIN

PRAVASTATIN: 作品数：36被引量：104H指数：6; 导出分析报告; 相关领域：医药卫生更多>>; 相关作者：郑朝余琴陈璧郑舒展李家富更多>>; 相关机构：南昌大学第四军医大学西京医院泸州医学院附属医院北京电力医院更多>>; 相关期刊：《Hepatobiliary & Pancreatic Diseases International》《Chinese Medical Journal》《World Journal of Diabetes》《World Journal of Pediatrics》更多>>; 相关基金：国家自然科学基金更多>>

无老年痴呆症的老年患者的认知功能与生存状况刘青(译),叶鹏(摘,审校)被引量：1: 《中华高血压杂志》2019年第7期614-614,共1页刘青(译) 叶鹏(摘/审校) Rostamian S de Haan S van der Grond J van Buchem MA Ford I Jukema JW Sabayan B; 特定区域认知功能的损害与死亡风险的增加相关。该研究前瞻性地评估了无痴呆老年受试者执行功能和记忆与长期死亡率的关系。此外,研究者调查了结构性大脑异常在这种关联中的作用。研究者纳入了547名无痴呆受试者(平均年龄78岁,男性占56....; 关键词：老年痴呆症认知功能老年患者 PRAVASTATIN 磁共振成像死亡风险执行功能大脑异常

Role of mammalian target of rapamycin signaling pathway in regulation of fatty acid oxidation in a preeclampsia-like mouse model treated with pravastatin被引量：8: 《Chinese Medical Journal》2019年第6期671-679,共9页Jing Huai Zi Yang Yan-Hong Yi Guang-Jiao Wang; grants from the National Natural Science Foundation of China (No. 81370723);Beijing Municipal Natural Science Foundation (No. 7132215).; Background: Fatty acid oxidation (FAO) disorder is involved in the pathogenesis of some cases of preeclampsia (PE). Several show that mammalian target of rapamycin (mTOR) signaling pathway is related to FAO. Pravastat...; 关键词：PREECLAMPSIA MTOR SIGNALING pathway PRAVASTATIN FATTY acid oxidation

Pravastatin激活自噬抑制糖皮质激素引起的髓核细胞凋亡: 《中国细胞生物学学报》2019年第1期53-62,共10页王小英焦丽艳付治安王彦华; 邯郸市科技局计划内项目(批准号:1723208067-2)资助的课题~~; 地塞米松注射可以缓解椎间盘退变引起的腰痛症状,但是具有一定的副作用。普伐他汀(Pravastatin)被发现可以缓解骨关节炎的炎症和症状,但是其对髓核细胞及椎间盘退变的作用及其机制尚不清楚。该文培养SD大鼠原代髓核细胞,用不同浓度地塞...; 关键词：髓核细胞普伐他汀地塞米松氧化应激

Pravastatin alleviates lipopolysaccharide-induced placental TLR4 over-activation and promotes uterine arteriole remodeling without impairing rat fetal development被引量：7: 《The Journal of Biomedical Research》2018年第4期288-297,共10页Muyi Yang Zhenyu Diao Zhiyin Wang Guijun Yan Guangfeng Zhao Mingming Zheng Anyi Dai Yimin Dai Yali Hu; funded by the following Grants:National Natural Science Foundation of China,Grant/Award Number:81370724,81571463 and 81401225;Innovative Research Program for Postgraduate in Higher Education Institutions of Jiangsu Province for the year 2016,Grant/Award Number:KYLX16_1111; Preeclampsia is associated with over-activation of the innate immune system in the placenta,in which toll-like receptor 4（TLR4） plays an essential part.With their potent anti-inflammatory effects,statins have been s...; 关键词：PREECLAMPSIA arteriole remodeling pravastatin toll-like receptor 4 fetal development

Limited Effect of Intravenously Administered Indoxyl Sulfate, a Uremic Toxin, on the Hepatic Transport of Pravastatin in Normal Rats: 《Pharmacology & Pharmacy》2018年第7期270-278,共9页Hideyuki Suga Yuichi Ichimura Satomi Otsuka Kaori Sugaya Masako Oda Hiroshi Saitoh; Indoxyl sulfate (IS) is a typical uremic toxin that extensively accumulates in the plasma of patients with seriously impaired renal function. This study seeks to clarify whether IS exerts a potent modulating effect on...; 关键词：Indoxyl SULFATE PRAVASTATIN DRUG Interaction HEPATIC Transport BILIARY EXCRETION

Different Effects of Pravastatin on Preeclampsia-like Symptoms in Different Mouse Models被引量：9: 《Chinese Medical Journal》2018年第4期461-470,共10页Jing Huai Zi Yang Yan-Hong Yi Guang-Jiao Wang; This work was supported by grants from the National Natural Science Foundation of China （No. 81370723）, and Beijing Municipal Natural Science Foundation （No. 7132215）.; Background： Pravastatin （Pra） exerts protective effects on preeclampsia. Preeclampsia is a multifactorial and pathogenic pathway syndrome. The present study compared the effects of Pra on clinical manifestations of...; 关键词：LIPIDS MOUSE PRAVASTATIN PREECLAMPSIA

Response to comment on: Statin use and risk of diabetes mellitus: 《World Journal of Diabetes》2016年第18期481-482,共2页Bharti Chogtu Rahul Magazine Kurady Laxminarayana Bairy; In letter to the editor "Comment on: Statin use andrisk of diabetes mellitus" authors found the statement "pravastatin 40 mg/d reduced the risk of diabetes by 30% in West of Scotland Coronary Prevention study" erroneo...; 关键词：PRAVASTATIN DIABETES MELLITUS

Comment on: Statin use and risk of diabetes mellitus被引量：2: 《World Journal of Diabetes》2016年第8期175-176,共2页Mehmet Ali Eren Tevfik Sabuncu Hüseyin Karaaslan; In manuscript named "Statin use and risk of diabetes mellitus" by Chogtu et al, authors defined that pravastatin 40 mg/dL reduced the risk of diabetes by 30% in West of Scotland Coronary Prevention study. In fact, pra...; 关键词：PRAVASTATIN STATINS Diabetes MELLITUS Coronary heart disease Myocardial INFARCTION

长期使用普伐他汀治疗冠状动脉性心脏病患者的有效性和安全性评估:16年随访研究: 《中华高血压杂志》2016年第4期399-399,共1页Hague WE Simes J Kirby A Keech AC White HD Hunt D Nestel PJ Colquhoun DM Pater H Stewart RA Sullivan DR Thompson PL West M Glasziou PP Tonkin AM 刘莉叶鹏; 该研究对普伐他汀长期干预缺血性疾病（Longterm intervention with pravastatin in ischaemicdisease，LIPID）临床研究中的受试者进行长期随访，评估他汀类药物治疗对全因死亡、特定病因死亡和癌症发生率的长期影响。; 关键词：安全性评估普伐他汀药物治疗心脏病患者冠状动脉性随访研究 PRAVASTATIN 有效性

Simvastatin,atorvastatin,and pravastatin equally improve the hemodynamic status of diabetic rats被引量：1: 《World Journal of Diabetes》2015年第10期1168-1178,共11页María J Crespo José Quidgley; Supported by MBRS-RISE,No.R25-GM061838;and RCMI,No.G12-RR03051; AIM: To investigate if the effect of statins improving cardiovascular(CV) status of diabetics is drug-specific or class-dependent, and the underlying mechanisms involved.MET HOD S : We compared the results of daily ad...; 关键词：STATINS Diabetes OXIDATIVE stress Cardiac function

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