PRAVASTATIN

作品数：36被引量：105H指数：6
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相关领域：医药卫生更多>>
相关作者：余琴郑舒展李家富冯健徐成斌更多>>
相关机构：南昌大学泸州医学院附属医院北京电力医院第四军医大学西京医院更多>>
相关期刊：《Hepatobiliary & Pancreatic Diseases International》《Chinese Medical Journal》《World Journal of Diabetes》《World Journal of Pediatrics》更多>>
相关基金：国家自然科学基金更多>>
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Role of mammalian target of rapamycin signaling pathway in regulation of fatty acid oxidation in a preeclampsia-like mouse model treated with pravastatin被引量：8
《Chinese Medical Journal》2019年第6期671-679,共9页Jing Huai Zi Yang Yan-Hong Yi Guang-Jiao Wang 
grants from the National Natural Science Foundation of China (No. 81370723);Beijing Municipal Natural Science Foundation (No. 7132215).
Background: Fatty acid oxidation (FAO) disorder is involved in the pathogenesis of some cases of preeclampsia (PE). Several show that mammalian target of rapamycin (mTOR) signaling pathway is related to FAO. Pravastat...
关键词：PREECLAMPSIA MTOR SIGNALING pathway PRAVASTATIN FATTY acid oxidation 
Different Effects of Pravastatin on Preeclampsia-like Symptoms in Different Mouse Models被引量：9
《Chinese Medical Journal》2018年第4期461-470,共10页Jing Huai Zi Yang Yan-Hong Yi Guang-Jiao Wang 
This work was supported by grants from the National Natural Science Foundation of China （No. 81370723）, and Beijing Municipal Natural Science Foundation （No. 7132215）.
Background： Pravastatin （Pra） exerts protective effects on preeclampsia. Preeclampsia is a multifactorial and pathogenic pathway syndrome. The present study compared the effects of Pra on clinical manifestations of...
关键词：LIPIDS MOUSE PRAVASTATIN PREECLAMPSIA 
Aspirin and pravastatin reduce lectin-like oxidized low density lipoprotein receptor-1 expression, adhesion molecules and oxidative stress in human coronary artery endothelial cells被引量：24
《Chinese Medical Journal》2010年第12期1553-1560,共8页CHEN Jia-wei ZHOU Shi-bei TAN Zhi-ming 
Background Oxidative stress and inflammation are important steps in the pathogenesis of atherosclerosis. We postulated that therapeutic concentrations of aspirin and pravastatin, especially in combination, may suppres...
关键词：ASPIRIN endothelial dysfunction HMG CoA reductase inhibitor INFLAMMATION oxidative stress 
Pravastatin activates platelet nitric oxide synthase (NOS) in patients with type 2 diabetes mellitus and NOS activation is accompanied by serine phosphorylation被引量：1
《Chinese Medical Journal》2005年第19期1654-1657,共4页YAO Kang XU Biao Gao Ling GE Jun-bo 
Statins cause reductions in myocardial infarction and also morbidity and mortality of type 2diabetes related to atheromatous disease and its thrombotic complications beyond those predicted by reductions in low density...
关键词：PLATELET HMG-CoA reductase inhibitors type 2 diabetes mellitus nitric oxide synthase 
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