Major depressive disorder(MDD)and type 2 diabetes(T2D)are two common complex multifactorial disorders that share several genetic and environmental risk factors such as hypercortisolism and related genes'riskvariants w...
Introduction: In the context of pituitary adenoma, bacterial meningitis is a possible complication of surgical or medical treatment. The occurrence of meningitis before any treatment is exceptional, explained by the e...
National Natural Science Foundation of China,Grant/Award Number:81700045,81870042 and 81900050;Natural Science Foundation of Shanghai,Grant/Award Number:22ZR1452400;Shanghai Municipal Commission of Health,Grant/Award Number:20204Y0384;Shanghai Pulmonary Hospital,Grant/Award Number:fk18003 and fkyq1605。
Prolactin(PRL)is a polypeptide hormone that is mainly synthesized and secreted by the lactotroph cells of the pituitary.There are two main isoforms of PRL:23-kDa PRL(named full-l ength PRL)and vasoinhibins(including ...
A long-held belief is that pituitary hormones bind to their cognate receptors in classical target glands to actuate their manifold functions.However,a number of studies have shown that multiple types of pituitary horm...
Objective: To illustrate the association between prolactin serum level and severity of preeclampsia. Methods: In this cross-sectional study, 31 pregnant women with preeclampsia were enrolled as GroupⅠand 20 healthy p...
Objective: To evaluate the anti-hyperprolactinemic effect of methanolic extract of Tinospora cordifolia against antipsychotic/neuroleptic drug induced hyperprolactinemia. Methods: A total of 48 Wistar albino rats were...
Neuropsychiatric systemic lupus erythematosus (NP-SLE) is one of the major cause of morbidity in systemic lupus erythematosus patients and its treatment depends on identification of pathogenic mechanisms. We describe ...
ThisworkwassupportedbytheNaturalScienceFoundationofLiaoningProvince (No 962 2 91)
Objective To study the effects of prolactin(PRL) on HLA-DR and CD40 expressions by human thyrocytes,and to investigate the possible mechanisms for PRL to affect the development of Graves'disease(GD).Methods Thyrocytes...