云南高校图书馆联盟文献共享服务平台- PROTEIN

PROTEIN_EXPRESSION: 作品数：291被引量：759H指数：12; 导出分析报告; 相关作者：顾芝萍冷颖瞿秋霞张学光董琦更多>>; 相关机构：中国科学院上海生命科学研究院北京大学中国医科大学附属第一医院深圳市慢性病防治中心更多>>; 相关期刊：更多>>; 相关基金：国家自然科学基金国家重点基础研究发展计划广东省自然科学基金国家教育部博士点基金更多>>

Systematic analysis of protein expression in Candida albicans exposed to farnesol被引量：5: 《Chinese Medical Journal》2019年第19期2348-2353,共6页Feng-Juan Wang Zhao-Hui Liu; This work was supported by a grant from the National Natural Science Foundation of China(No.81571394).; Background:The phenotypic switching of Candida spp.plays an important role in the development of vulvovaginal candidiasis(VVC).Farnesol,as a quorum-sensing molecule in Candida albicans,has the ability to prevent yeast...; 关键词：FARNESOL CANDIDA ALBICANS PROTEOMIC analysis MORPHOGENESIS

Increased 5-hydroxymethylcytosine and Ten-eleven Translocation Protein Expression in Ultraviolet B-irradiated HaCaT Cells被引量：2: 《Chinese Medical Journal》2017年第5期594-599,共6页Dan Wang Jin-Hua Huang Qing-Hai Zeng Can Gu Shu Ding Jian-Yun Lu Jing Chen Sheng-Bo Yang; Background： DNA hydroxymethylation refers to a chemical modification process in which 5-methylcytosine （5mC） is catalyzed to 5-hydroxymethylcytosine （5hmC） by ten-eleven translocation （TET） family proteins. Rec...; 关键词：5-hydroxymethylcytosine 5-methylcytosine DNA Hydroxymethylation Ten-eleven Translocation Ultraviolet B

Proteomic analysis of the alteration of protein expression in the placenta of Down syndrome: 《Chinese Medical Journal》2011年第22期3738-3745,共8页SUN Cheng-juan YAN Li-yu WANG Wei YU Song WANG Xin ZHANG Wei-yuan; This-work was supported by grants from the Youth Science Foundation of China （No. 81100445）, Talents Project of Beijing Health Bureau （No. 2009-2-11） and the Basic and Clinical Research Cooperation Fund of Capital Medical University （No. 11JL54）.; Background Down syndrome （DS） is the most common form of human aneuploidy, and there is no effective therapy for the chromosomal abnormalities. We aimed to unravel the molecular mechanisms underlying DS and to provi...; 关键词：Down syndrome PLACENTA proteomics two-dimensional difference gel electrophoresis Matrix-assisted laser desorption/ionization

Associations between gene polymorphisms of thymidylate synthase with its protein expression and chemosensitivity to 5-fluorouracil in pancreatic carcinoma cells被引量：4: 《Chinese Medical Journal》2011年第2期262-267,共6页ZHANG Qiang ZHAO Yu-pei LIAO Quan HU Ya XU Qiang ZHOU Li SHU Hong; Background Thymidylate synthase （TS） is a key regulatory enzyme for de novo DNA synthesis.TS activity is also an important determinant of the response to chemotherapy with fluoropyrimidine prodrugs,and its expressio...; 关键词：thymidylate synthase gene polymorphisms pancreatic carcinoma

Clinical significance of PHPT1 protein expression in lung cancer被引量：5: 《Chinese Medical Journal》2010年第22期3247-3251,共5页XU An-jian XIA Xiang-hou DU Song-tao GU Jun-chao; This work was supported by the grants from Capital Foundation for Development of Medical Science （No. 2005-2031） and National Natural Science Foundation of China （No. 30772121）.; Background In our previous studies, we found the expression of 14-kD phosphohistidine phosphatase （PHPT1） was associated with lung cancer cells migration and invasion, and PHPT1 mRNA expression level in lung cancer ...; 关键词：PHPT1 protein lung cancer IMMUNOHISTOCHEMISTRY

Quantitative differences in protein expression between cisplatin sensitive COC1 ovarian carcinoma cells and cisplatin resistant COC1/DDP cells: 《Chinese Medical Journal》2009年第7期865-869,共5页WANG Hui-xiang SUN Wei LI He-lian ZHANG Wei-yuan; Ovarian cancer is the second most common cancer of the reproductive system in women and is the leading cause of death from gynecological cancers. Despite good response to surgery and initial chemotherapy, the resistan...; 关键词：CHEMORESISTANCE ovarian cancer proteomics molecular markers gel electrophoresis

Inhibition of proliferation and transforming growth factor β3 protein expression by peroxisome proliferators-activated receptor γ ligands in human uterine leiomyoma cells被引量：2: 《Chinese Medical Journal》2008年第2期166-171,共6页ZHANG Chun-hua WEN Ze-qing LI Jian-feng LI Chang-zhong SHI Min YANG Gui-wen LAN Shou-min ZHU Yong WANG Fei ZHANG Yao-jing WANG Ying-ying ZHANG Hui; This work was supported by the Natural Science Foundation of Shandong Province （No.Y2006C67）.; Background Rosiglitazone is known as the most potent and specific peroxisome proliferators-activated receptor γ （PPAR-γ） ligand. It has potentially far-reaching effects on pathophysiological processes, from cancer...; 关键词：UTERUS LEIOMYOMA peroxisome proliferators-activated receptor γ transforming growth factor β3

Vascular endothelial growth factor mRNA and its protein expression in decidua after terminating early pregnancy by mifepristone plus misoprostol: 《Chinese Medical Journal》2001年第5期69-71,109,共4页黄丽丽石一复; Objective To investigate the action of mifepristone plus misoprostol on decidua at the level of vascular endothelial growth factor (VEGF) mRNA and its protein expression, as well as the mechanism of prolonged uterine ...; 关键词：mifepristone · vascular endothelial growth factor · decidua · uterine hemorrhage

Increased expression of Hsp70 and co-localization with nuclear protein in cells infected with the Hantaan virus: 《Chinese Medical Journal》2001年第5期87-91,111,共6页叶苓刘彦仿廖文俊杨守京王春梅; agrantfromtheNationalNaturalScienceFoundationofChina (No 3 9770 664 ); Objective To investigate the effect of Hantaan virus infection on the expression of stress genes. Methods Techniques of virus infection, Western blot, immunohistochemistry, dual-immunofluorecsence staining, laser scan...; 关键词：heat shock protein 70 · Hantaan virus · protein expression

Molecular cloning and protein expression of EC1-2 and EC3-4 epitopes of pemphigus vulgaris antigen被引量：1: 《Chinese Medical Journal》2000年第11期51-54,共4页郑捷康向东李卫平陈颖唐敏珠周文瑜; This project was supported by the grants fam the Healh Administration of Shanghai(Na 98BR037); the National Natural Science Faundatian of China(Na 39870665).; To clone and express EC1 2 and EC3 4 epitopes of PVA (pemphigus vulgaris antigen, desmoglein 3) in order to diagnose pemphigus and study the relationship between epitopes of PVA and anti PVA antibody Methods RN...; 关键词：PEMPHIGUS pemphigus vulgaris antigen desmoglein-3 EPITOPE

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