云南高校图书馆联盟文献共享服务平台- PROTEIN

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Efficient Chemical Synthesis and Folding of Mirror-Image Tropomyosin Receptor Kinase A Using the Strategy of Removable Glycosylation Modification: 《Chinese Journal of Chemistry》2024年第19期2316-2322,共7页Tongyue Wang Weiwei Shi Guo-Chao Chu Yi-Ming Li; supported by the National Natural Science Foundation of China(Nos.22227810,22277020,22307061);China Postdoctoral Science Foundation(No.2022M721801);the Beijing Life Science Academy(No.2023000cc0130).; Comprehensive Summary The strategy of removable glycosylation modification was used to overcome the low-efficiency problem encountered in the chemical synthesis of the mirror-image D-version of the immunoglobulin(Ig)-...; 关键词：Chemical protein synthesis Removable glycosylation modification Synthetic methods Protein folding D-protein

Single Molecule Thermodynamics Hypothesis of Protein Folding and Drug Design: 《Journal of Biosciences and Medicines》2019年第11期164-172,共9页Fang Yi; 关键词：Protein FOLDING CONFORMATION THERMODYNAMIC System Gibbs Free Energy Single Molecule MACROSCOPIC Quantum Statistics

The Important Roles of Water in Protein Folding:an Approach by Single Molecule Force Spectroscopy被引量：2: 《Chinese Journal of Polymer Science》2018年第3期379-384,共6页Bo Cheng Shu-Xun Cui; financially supported by the National Natural Science Foundation of China(Nos.21574106 and 21604074);the Sichuan Province Youth Science and Technology Innovation Team(Nos.2016TD0026 and 2017JQ0009); The single-chain elasticity of a completely unfolded protein （027）8, modules of human cardiac titin） is studied in different liquid environments by the atomic force microscopy （AFM）-based single molecule force sp...; 关键词：SMFS PROTEIN FOLDING WATER

Quantum conformational transition in biological macromolecule: 《Frontiers of Electrical and Electronic Engineering in China》2017年第2期143-158,共16页Liaofu Luo Jun Lv; Background： Recently we proposed a quantum theory on the conformational change of biomolecule, deduced several equations on protein folding rate from the first principles and discussed the experimental tests of the t...; 关键词：conformational change quantum transition protein folding RNA folding temperature dependence

Role of Interfacial Viscosity and pH in L-Phenylalanine,L-Tryptophan Molecular Rotors: 《光谱学与光谱分析》2016年第5期1629-1633,共5页N.Meenakshisundaram Kamatchi Sankaranarayanan; Protein folding involves the aminoacid sequence to come forth and form an energy minimized structure.Recently molecular crowding leading to increase in viscosity is said to be one of the major concerns affecting prote...; 关键词：Protein folding Molecular crowders Interfacial viscosity Fluorescent probes

Thermodynamic Principle Revisited: Theory of Protein Folding: 《Advances in Bioscience and Biotechnology》2015年第1期37-48,共12页Yi Fang; Anfinsen’s thermodynamic hypothesis is reviewed and misunderstandings are clarified. It really should be called the thermodynamic principle of protein folding. Energy landscape is really just the mathematical graph o...; 关键词：PROTEIN FOLDING Gibbs Free Energy QUANTUM Statistic Single MOLECULE

Tightening up the structure, lighting up the pathway:application of molecular constraints and light to manipulate protein folding, self-assembly and function: 《Science China Chemistry》2014年第12期1615-1624,共10页MARKIEWICZ Beatrice N. CULIK Robert M. GAI Feng; supported by the National Institutes of Health(GM-065978,AG-039253); Chemical cross-linking provides an effective avenue to reduce the conformational entropy of polypeptide chains and hence has become a popular method to induce or force structural formation in peptides and proteins.Rec...; 关键词：protein folding aggregation SELF-ASSEMBLY CROSS-LINKER phototrigger light-activation

Physicochemical bases for protein folding,dynamics,and protein-ligand binding被引量：2: 《Science China(Life Sciences)》2014年第3期287-302,共16页LI HuiMin XIE YueHui LIU CiQuan LIU ShuQun; supported by the National Natural Science Foundation of China(31370715,31160181,31360277,30860011);the National Basic Research Program of China(2013CB127500);the Program of Innovation Group of Yunnan Province(2011CI123);Foundation for Key Teacher in Yunnan University(XT412003); Proteins are essential parts of living organisms and participate in virtually every process within cells. As the genomlc sequences for increasing number of organisms are completed, research into how proteins can perfo...; 关键词：free energy landscape entropy-enthalpy non-complementarity RUGGEDNESS driving force thermodynamics kinetics

Tools for Protein Structure Prediction at the bri-shur.com Web Portal: 《Journal of Life Sciences》2012年第10期1174-1179,共6页Sergey Feranchuk Ulyana Potapova Vladimir Potapov Dmitry Mukha Vladimir Nikolaev Sergei Belikov; lntemet services on bioinformatics still remain a popular tool for the researchers. Here the authors present a recently developed web-site http：//bri-shur.com where several tools and pipelines for protein structure p...; 关键词：Web-service SOAP homology modeling homology screening protein folding.

Study on the chaperone properties of conserved GTPases: 《Protein & Cell》2012年第1期44-50,共7页Xiang Wang Jiaying Xue Zhe Sun Yan Qin Weimin Gong; by grants from the National Natural Science Foundation of China(Grant No.31170756);CAS-NN Research Foundation to Y.Qin.; As a large family of hydrolases,GTPases are widespread in cells and play the very important biological function of hydrolyzing GTP into GDP and inorganic phosphate through binding with it.GTPases are involved in cell ...; 关键词：protein folding CHAPERONE conserved GTPase

PROTEIN_FOLDING