the National Natural Science Foundation of China(Nos.22371007,22071005);the Peking University Medicine Fund for world's leading discipline or discipline clusterdevelopment(BMU2022DJXK002).
A mild and practical method for synthesizing fluorinated quinoline derivatives,which have a wide range of applications in pharmaceuticals,materials,and organic synthesis,was described through C—F bond insertion into ...
Staphylococcus aureus is a gram-positive pathogenic bacterium responsible for various infections including skin suppurations. Quinolones are sometimes used last in infections. The Staphylococcus aureus o...
the deanship of scientific Research at Princess Nourah bint Abdulrahman University through the Fast-track Research Funding program。
Quinolone has a broad spectrum of synthetic antibiotics with a strong therapeutic effect and quinolone is a term used for chemical treatments used to treat a powerful bacteria.Quinolones are divided into 4 generations...
A simple,easy and cost-efficient UV spectroscopic method was developed and validated for glibenclamide,the second generation of sulfonylureas,using 0.1 N NaOH as a solvent.The proposed method is linear(R^(2)>0.999)wit...
The stability of imidoyl radicals prepared from 2-(2-alkenyloxy)-phenyl selenoimidates and 2-(2-allylamino)-phenyl selenoimidates and their intramolecular free radical cyclization through the slow addition of tri-N-bu...
Acknowledgements This work is financially supported by the National Natural Science Foundation of China (Nos. 21522102,21503095, 21471068, 21371081, and 21301073), the Key Programs from MOST (Nos. 2016YFD0401101 and 2012YQ09019410), and grants from Natural Science Foundation of Jiangsu Province, MOF and MOE (Nos. BK20150145, BX20151038, BK20140003, BE2014672, BE2013613, BE2013611).
For rapid and simultaneous detection of (fluoro)quinolones, a broadly specific monoclonal antibody (mAb) that recognizes 32 (fluoro)quinolone antibiotics was prepared using a mixture of a norfloxacin derivative ...
the National Key Technology R&D Program‘‘New Drug Innovation’’of China(No.2013ZX09402103)
A novel and efficient approach for the straightforward synthesis of biologically significant acenaphtho[1,2-b]quinoline derivatives in good yields utilizing CuI as a catalyst with a broad array of substrates has been ...
The authors thank the financial support by Jiangsu National Science Foundation(No.BK2009239);The project was also funded by the Key Laboratory for the Chemistry and Molecular Engineering of Medicinal Resources(Guangxi Normal University);the Ministry of Education of China(No.CMEMR2013-B02).
First Ni(Ⅱ)ternary complex using the quinolone antibacterial agent enoxacin(HEn)as ligand and 1,10-phenanthroline as co-ligand has been synthesized and characterized.It is a mononuclear structure,in which enoxacin ac...
A method of on-line pretreatment coupled to HPLC with fluorescence detection was developed and validated for the determination of nine quinolones in honey samples. This method simplified the complicated process of sam...