以Ras同源基因家族成员C(Ras homolog gene family member C, RhoC)为靶点探讨栓菌酸(trametenolic acid, TA)对人肝癌HepG2.2.15细胞迁移侵袭的影响及机制,为栓菌酸的利用提供依据。采用MTT法检测TA对HepG2.2.15细胞增殖的影响;划痕实...
This work was supported by the National Science Foundation for Young Scientists of China(81702994);International S&T Cooperation Program of China(2015DFA30420);We thank Dr Ralph A.Reisfeld from the Scripps Research In stitute for his valuable suggestions and for proof-readi ng this manuscript.
Metastases are the main cause of cancer-related mortality in breast cancer.Although significant progress has been made in the field of tumor metastasis,the exact molecular mechanisms involved in tumor metastasis are s...
Supported by the National Natural Science Foundation of China,No.81201972;the China Postdoctoral Science Foundation,No.2013M531555;the Postdoctoral Science Foundation of Jiangxi province,No.2013KY44
AIM To clarify the underlying mechanism of formin-like 3(FMNL3)in the promotion of colorectal carcinoma(CRC)cell invasion.METHODS The in vitro biological function analyses of FMNL3 were performed by gain-and loss-of f...