supported by the grants from the Natural Science Foundation of China(No.31470034);the Natural Science Foundation of Fujian Province(No.2020J01022);the Joint Funds for the Innovation of Science and Technology,Fujian Province(No.2018Y9100);the Open Research Fund of State Key Laboratory of Cellular Stress Biology,Xiamen University(No.SKLCSB2020KF002).
Cefotetan is widely used to treat bacterial infections in the clinic owing to its broad spectrum of antibacterial activity.In the present study,we demonstrate that cefotetan can bind to the conserved ligand-binding po...
supported by the National Key R&D Program of China(2020YFC2005000);the National Natural Science Foundation of China(82070711);the Science/Technology Project of Sichuan province(2020YFQ0055);the 1.3.5 project for disciplines of excellence from West China Hospital of Sichuan University(ZYGD18027).
Enhancer of zeste homolog 2(EZH2),a component of polycomb repressive complex 2(PRC2),is a histone lysine methyltransferase mediating trimethylation of histone H3 at lysine 27(H3K27me3),which is a repressive marker at ...
supported by the National Natural Science Foundation of China(81972733);the Natural Science Foundation of Zhejiang Province(LY19H160048).
Aberrant inflammasome activation contributes to the pathogenesis of various human diseases,including atherosclerosis,gout,and metabolic disorders.Elucidation of the underlying mechanism involved in the negative regula...