The authors regret there was an unfortunate error in the reproduction of Fig.1I in the article.In the original figure,the fluorescence picture of the positive control drug-ifenprodil was misused.The authors have corre...
the National Natural Science Foundation of China(Grant No.:82204341);Chinese Academy of Medical Sciences Innovation Fund for Medical Sciences(Grant No.:2022-I2M-2-002);the National Key Research and Development Program of China(Grant No.:2019YFC1708901).
Abnormal synaptic plasticity causes cognitive deficits.Hippocampal long-term potentiation(LTP)is a critical synaptic plasticity process[1].Rescuing impaired LTP is challenging;hence,novel agents are required for LTP f...
financially supported by Foundation of Tianjin Municipal Education Commission(2019KJ058).
Background:Shengmai Yin(SMY)formula,a traditional Chinese medicine,shows a definite therapeutic effect on chronic heart failure(CHF)in clinical practice,but the molecular mechanism remains largely unknown.The PI3K/Akt...
National Natural Science Foundation of China (No.81803925);National Key Research and Development Program (No.2017YFC1700102)。
Objective:To systematically evaluate the clinical efficacy of oral Chinese patent medicine combined with sacubitril/valsartan in treating chronic heart failure(CHF).Methods:CNKI,CSPD,CCD,CBM,PubMed,Web of Science,Coch...
the National Natural Science Foundation of China(No.82074132);Project of Administration of Traditional Chinese Medicine of Guangdong Province of China(No.20213009);the Science and Technology Plan Project of Guangzhou City(No.202102080405)。
Objective: To investigate the mechanism by which Chinese medicine Shengmai Yin(SMY)reverses epithelial-mesenchymal transition(EMT) through lipocalin-2(LCN2) in nasopharyngeal carcinoma(NPC)cells CNE-2R. Methods: Morph...
We thank the National High-End Foreign Experts Recruitment Plan(G2022051012L);National Key Research and Development Program of China(2016YFE0131800);Science and Technology Department of Sichuan Province(2019YFH0023);the High-End Talents Recruitment Program(Liu Xinmin group)of Luzhou Municipal People's Government.
Background:Hyperglycemia is a characteristic feature of diabetes that often results in neuropsychological complications such as depression.Diabetic individuals are more vulnerable to experience depression compared to ...
Supported by Randomized,Double-blind,Placebo-controlled,Multicenter Clinical Study to Improve Symptoms Associated with Pulmonary Heart Function during Recovery from COVID-19(II)(No.2020ZYLCYJ08-4)。
OBJECTIVE:To evaluate the efficacy and safety of Shengmai Yin(生脉饮,SMY)on visual analogue scale(VAS)for cardiopulmonary symptoms in coronavirus disease 2019(COVID-19)convalescent patients.METHODS:In this randomized,...
Supported by the National Natural Science Foundation of China(No.81973689,No.82074254);the Beijing Natural Science Foundation of China(No.7202176)。
Objective:To systematically evaluate the efficacy of Shengmai San in patients with cardiotoxicity of anthracyclines.Methods:Randomized controlled trials(RCTs)were identified by searching China National Knowledge Infra...
supported by the National Natural Science Foundation of China(Grant Nos.:81673718 and 82074132);the Technology Project of Guangdong Province(Grant No.:2016A020226034)。
Shengmai Yin(SMY)is a Chinese herbal decoction that effectively alleviates the side effects of radiotherapy in various cancers and helps achieve radiotherapy’s clinical efficacy.In this study,we explored the interact...
the Ph.D.Start-up Fund of Guangdong Medical University(No.B2019016);the Administration of Traditional Chinese Medicine of Guangdong Province(No.20201180);the Science and Technology Special Project of Zhanjiang(No.2019A01009);the Natural Science Foundation of Guangdong Province(No.2016B030309002);the Basic and Applied Basic Research Program of Guangdong Province(No.2019A1515110201);the Educational Commission of Guangdong Province(No.4SG20138G);the Fund of Southern Marine Science and Engineering Guangdong Laboratory(Zhanjiang)(No.ZJW-2019-007).
Background:Studies have shown that,Shengmai injection(Shengmai decoction)which has been included in the diagnosis and treatment of coronavirus disease 2019(COVID-19),is effective in the early treatment of patients wit...