SMOOTH_MUSCLE_CELLS

作品数:141被引量:376H指数:10
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相关作者:司履生季军方卫华令文萍黄聿更多>>
相关机构:南京医科大学武汉大学哈尔滨医科大学上海交通大学更多>>
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Impact of sodium-glucose cotransporter-2 inhibitors on pulmonary vascular cell function and arterial remodeling
《World Journal of Cardiology》2025年第1期28-46,共19页Jing-Jing Zhang Xue-Rui Ye Xue-Song Liu Hao-Ling Zhang Qian Qiao 
Supported by Science and Technology Department of Yunnan Province-Kunming Medical University,Kunming Medical Joint Special Project-Surface Project,No.202401AY070001-164;Yunnan Provincial Clinical Research Center Cardiovascular Diseases-New Technology Research for Development Project for Diagnosis and Treatment Cardiovascular Diseases,No.202102AA310002;the Key Technology Research and Device Development Project for Innovative Diagnosis and Treatment of Structural Heart Disease in the Southwest Plateau Region,No.202302AA310045.
Sodium-glucose cotransporter-2(SGLT-2)inhibitors represent a cutting-edge class of oral antidiabetic therapeutics that operate through selective inhibition of glucose reabsorption in proximal renal tubules,consequentl...
关键词:Sodium-glucose cotransporter-2 inhibitors Pulmonary vascular endothelial cells Pulmonary vascular smooth muscle cells Pulmonary artery remodeling Right heart dysfunction Cardiovascular disease 
Microscopic Structure of the Sigmoido-Jugular Junction in the Third-Trimester Fetus
《Open Journal of Modern Neurosurgery》2024年第4期267-274,共8页Léon Boukassa Ruth Ibara Wame Bejart Evayoulou-Kouamvi Fabien Gaël Mouamba Oldany Lizen Mozoma Eloge Mbongo Backobi 
Context and Justification: The sigmoido-jugular junction connects two structures of different compositions and has a complex organization. The sinusoidal portion of its endothelium contains muscle cells in adults. Is ...
关键词:Sigmoido-Jugular Junction Venous Drainage Sigmoid Endothelium Smooth Muscle Cells 
Novel Role of Calcium-Sensitive Receptors in Chronic Hypoxia-Induced Proliferation of Pulmonary Vein Smooth Muscle Cells
《Journal of Clinical and Nursing Research》2024年第7期349-355,共7页Shaoxing Li Jurong Zhang Zhuandi Lin Zhiming Xiang Gongyong Peng 
Guangzhou Municipal Health Science and Technology Project(Project No.20211A010087);Guangzhou Panyu District Science and Technology Program Project(Project No.2020-Z04-012)。
Objective:Vascular remodeling due to chronic hypoxia(CH)occurs not only in the pulmonary arteries but also in the pulmonary veins.Pulmonary vascular remodeling arises from the proliferation of pulmonary vascular myocy...
关键词:Hypoxia Calcium-sensitive receptor(CaSR) Pulmonary hypertension Cell proliferation Calcium ions 
Influence of Angiotensin II on &#945;<sub>1</sub>-Adrenergic Receptors Function in Rat Aorta and Expression in Vascular Smooth Muscle Cells
《Journal of Biosciences and Medicines》2024年第4期123-134,共12页Itzell Alejandrina Gallardo-Ortíz Juan Pablo de Jesús Benítez-Garrido Santiago C. Sigrist-Flores Juan Javier López-Guerrero Enrique Hong Rafael Villalobos-Molina 
Angiotensin II (Ang II) is the main mediator of the Renin-Angiotensin-System acting on AT1 and other AT receptors. It is regarded as a pleiotropic agent that induces many actions, including functioning as a...
关键词:Angiotensin II α1D-AR α1-AR Expression Rat aorta Smooth Muscle Cells 
Advances in the differentiation of pluripotent stem cells into vascular cells
《World Journal of Stem Cells》2024年第2期137-150,共14页Yi-Chang Jiao Ying-Xin Wang Wen-Zhu Liu Jing-Wen Xu Yu-Ying Zhao Chuan-Zhu Yan Fu-Chen Liu 
Blood vessels constitute a closed pipe system distributed throughout the body,transporting blood from the heart to other organs and delivering metabolic waste products back to the lungs and kidneys.Changes in blood ve...
关键词:Induced pluripotent stem cell Blood vessels Vascular organoids Endothelial cells Smooth muscle cells PERICYTES Tissue engineering vascular graft 
N-acetylcysteine ameliorates erectile dysfunction in rats with hyperlipidemia by inhibiting oxidative stress and corpus cavernosum smooth muscle cells phenotypic modulation
《Asian Journal of Andrology》2024年第1期99-106,共8页Wei Ding Jun-Hong Fan Li-Ren Zhong Nan-Xiong Wang Lu-Hao Liu Hai-Bo Zhang Li Wang Ming-Qiang Wang Bing-Lin He An-Yang Wei 
This work is supported by a grant from the National Natural Science Foundation of China(No.82060809);the Natural Science Foundation of Guangdong Province(No.2017A030313453 and No.2018A030313638);Guangzhou Basic and Applied Basic Research Foundation(No.202102020417).
Hyperlipidemia is a major risk factor for erectile dysfunction(ED).Oxidative stress and phenotypic modulation of corpus cavernosum smooth muscle cells(CcSMCs)are the key pathological factors of ED.N-acetylcysteine(NAC...
关键词:erectile dysfunction HYPERLIPIDEMIA N-ACETYLCYSTEINE oxidative stress henotypic modulation 
NR4A1 enhances glycolysis in hypoxia-exposed pulmonary artery smooth muscle cells by upregulating HIF-1αexpression
《BIOCELL》2023年第11期2423-2433,共11页CHENYANG CHEN JUAN WEN WEI HUANG JIANG LI 
supported by the National Natural Science Foundation of China(No.82000300).
Background:Pulmonary arterial hypertension(PAH)is a chronic and progressive disease that is strongly associated with dysregulation of glucose metabolism.Alterations in nuclear receptor subfamily 4 group A member 1(NR4...
关键词:Pulmonary arterial hypertension NR4A1 HIF-1Α GLYCOLYSIS HYPOXIA Pulmonary arterial smooth muscle cells 
Inhibitory Effect of PPARδAgonist GW501516 on Proliferation of Hypoxia-induced Pulmonary Arterial Smooth Muscle Cells by Regulating the mTOR Pathway被引量:1
《Current Medical Science》2023年第5期979-987,共9页Chang-gui CHEN Chun-feng YI Chang-fa CHEN Li-qun TIAN Li-wei LI Li YANG Zuo-min LI Li-qun HE 
supported by the National Natural Science Foundation of Hubei Province(No.2018CFC801).
Objective This study aimed to investigate the effects of the peroxisome proliferator-activated receptorδ(PPARδ)agonist GW501516 on the proliferation of pulmonary artery smooth muscle cells(PASMCs)induced by hypoxia,...
关键词:peroxisome proliferator-activated receptorδ GW501516 HYPOXIA pulmonary artery smooth muscle cells PROLIFERATION mammalian target of rapamycin 
IGF-1 inhibited the apoptosis of gastric smooth muscle cells induced by high glucose through AMPK-Akt-mTOR pathway
《China Medical Abstracts(Internal Medicine)》2023年第2期90-90,共1页张香子 
Objective To investigate the effect of insulin-like growth factor 1(IGF-1)on rat gastric smooth muscle cell apoptosis and key proteins of AMPK-Akt-mTOR pathway and to explore the related mechanisms.Methods Rat gastric...
关键词:mTOR AMPK APOPTOSIS AKT 
Trehalose attenuates abdominal aortic aneurysm formation by inducing autophagy in smooth muscle cells
《Journal of Geriatric Cardiology》2023年第3期214-222,共9页Bo JIANG Xuan LI Mo WANG Guang-Xin LI Peng-Wei REN Yu-Qi WANG Shi-Jie XIN Ling-Feng QIN 
supported by National Natural Science Foundation of China(grant no.81974049).
BACKGROUND Trehalose is a naturally occurring disaccharide,which has been identified as an autophagy inducer and ex-hibits protective effect in cardiovascular diseases such as myocardial infraction and atherosclerosis...
关键词:ABDOMINAL ANEURYSM protective 
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