SOMATIC

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Armed T cells with CAR for cancer immunotherapy
《Science China(Life Sciences)》2016年第4期331-332,共2页Yu-Quan Wei 
The development of genetic engineering has enabled the modification of stem cells and somatic cells.T cells exert immune responses against cancer cells.Efforts to redirect T cell specificity of a chimeric antigen rece...
关键词：immunotherapy refractory somatic lymphoid desired fight exert specificity enabled myeloma 
Current progress and prospects of induced pluripotent stem cells被引量：11
《Science China(Life Sciences)》2009年第7期622-636,共15页CHEN LingYi & Liu Lin Key Laboratory of Bioactive Materials of Ministry of Education,College of Life Sciences,Nankai University,Tianjin 300071,China 
Supported by the National Key Basic Research and Development Program of China (Grant No. 2009CB941000);the Ministry of Science and Technology of China, and the transgenic program (Grant No. 2009ZX08006-010B);the National Natural Science Foundation of China (Grant No. 90919009);the Ministry of Agriculture of China (Grant No. 2009ZX08006-011B)
Induced pluripotent stem(iPS) cells are derived from somatic cells by ectopic expression of few transcription factors.Like embryonic stem(ES) cells,iPS cells are able to self-renew indefinitely and to differentiate in...
关键词：induced PLURIPOTENT stem(iPS) cells SOMATIC cell REPROGRAMMING PLURIPOTENCY 
Production of transgenic cashmere goat embryos expressing red fluorescent protein and containing IGF1 hair-follicle-cell specific expression cassette by somatic cell nuclear transfer被引量：2
《Science China(Life Sciences)》2009年第4期390-397,共8页BOU ShorGan 
Supported by the National High Technology Research and Development Program of China (Grant No. 2002AA242061) ;Natural Science Foundation of Inner Mongo-lia (Grant No. 200607010405)
In the present study, cashmere goat fetal fibroblasts were transfected with pCDsR-KI, a hair-follicle-cell specific expression vector for insulin-like growth factor 1 (IGF1) that contains two markers for selection (re...
关键词：CASHMERE goat insulin like growth factor 1 HAIR follicle fetal fibroblasts cells TRANSGENE SOMATIC cell nuclear transfer 
Transfer of small chromosome fragments of Agropyron elongatum to wheat chromosome via asymmetric somatic hybridization被引量：5
《Science China(Life Sciences)》2004年第5期434-441,共8页WANG Jing,XIANG Fengning,XIA Guangmin & CHEN Huimin School of Life Sciences,Shandong University,Jinan 250100,China 
This work was supported by the National Natural Science Foundation of China(Grant No.30370857);Major Project of Ministry of Education in China;National 863 High Technology Research and Development Project(No.2001AA241032).
The chromosome constitution of hybrids and chromation patterns of Agropyro-nelelongatum(Host)Neviski in F5 somatic hybrid lines Ⅱ -1-3 and l-1-9 between Triticum aesti-vum L.and A.elongatum were analyzed.Based on the...
关键词：TRITICUM AESTIVUM L. Agropyron elongatum(Host)Neviski F5 SOMATIC hybrid lines small CHROMOSOME segment translocation in situ hybridization simple sequence repeat. 
Production of transgenic blastocyst by nuclear transfer from different types of somatic cells in cattle被引量：19
《Science China(Life Sciences)》2004年第2期183-189,共7页GONG Guochun1, DAI Yunping1, FAN Baoliang1, ZHU Huabing2, WANG Haiping3, WANG Lili1, FANG Changge1, WAN Rong3, LIU Ying3, LI Rong3 & LI Ning1 1. State Key Laboratory for Agrobiotechnology, China Agricultural University, Beijing 100094, China 2. Institute of Animal Science, Chinese Academy of Agricultural Sciences, Beijing 100094, China 3. Gentitan Biotechnology Ltd., Beijing 100084, China 
The present study examined the effects of genetic manipulation to the donor cell and different types of transgenic donor cells on developmental potential of bovine nuclear trans-fer (NT) embryos. Four types of bovine ...
关键词：transgenic  nuclear transfer  SOMATIC cells  EGFP  blastocyst  bovine. 
The giant panda (Ailuropoda melanoleuca) somatic nucleus can dedifferentiate in rabbit ooplasm and support early development of the reconstructed egg被引量：22
《Science China(Life Sciences)》1999年第4期346-353,共8页陈大元 孙青原 刘冀珑 李光鹏 廉莉 王敏康 韩之明 宋祥芬 李劲松 孙强 陈玉村 张亚平 丁波 
Project supported by the 1998 Special Fund of the Chinese Academy of Sciences (KY95-J1-318);a 1999 Special Fund from the Ministry of Science;Technology.Instruments were dominated by Mr. Shum Yam Wa, Heal Force Development Ltd
The giant panda skeletal muscle cells, uterus epithelial cells and mammary gland cells from an adult individual were cultured and used as nucleus donor for the construction of interspecies embryos by transferring them...
关键词：giant panda RABBIT INTERSPECIES doning DEDIFFERENTIATION totipotency. 
Asymmetric somatic hybridization between Triticum aestivum L. and Haynaldia villosa Schur被引量：7
《Science China(Life Sciences)》1996年第6期617-626,共10页周爱芬 夏光敏 陈惠民 
Project supported by the Commission of Science of Shandong Province.
Suspension cell-derived protoplasts of wheat, inactivated with different concentrations (0-2.5mol/L) of IOA, were fused by PEG method with the Haynaldia villosa protoplasts which originated from the calli 4-5d after s...
关键词：WHEAT (T. aestivum) Haynaldia villosa asymmetric SOMATIC HYBRIDIZATION plant regeneration. 
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