the Max Planck Society(Y.Z-.,S.A.,L.P.d.S.,F.S.,and A.R.F.),and Y.Z.,S.A.,and A.R.F.acknowledge the European Union's Horizon 2020 research and innovation programme,project PlantaSYST(SGA-CSA No.739582 under FPA No.664620);the BG05M2OP001-1.003-001-C01 project,financed by the European Regional Development Fund through the Bulgarian"Science and Education for Smart Growth"Operational Programme.J.J.M.thanks the Fonds der Chemischen Industrie,FCI for funding,H.F.thanks the Chinese Scholarship Councilfor funding.
The diterpenoid paclitaxel(Taxol)is a chemotherapy medication widely used as a first-line treatment against several types of solid cancers.The supply of paclitaxel from natural sources is limited.However,missing knowl...
Supported by Special Key Project for Technological Innovation and Application Development in Chongqing City (cstc2021jscx-tpyzxX0017).
At the Taxus base of Pengshui Miao and Tujia Autonomous County,Chongqing,the comprehensive development and utilization of Taxus was carried out with seedling cultivation,understory economy,product processing,ecotouris...
funded by the National Natural Science Foundation of China(32271905 and 32270382);the Zhejiang Provincial Natural Science Foundation of China under grants LY23C160001,LY18C050005,LY19C150005,and LY19C160001;the Opening Project of Zhejiang Provincial Key Laboratory of Forest Aromatic Plant-Based Healthcare Functions(2022E10008);the Open Foundation of State Key Laboratory of Subtropical Silviculture,Zhejiang A&F University(KF201708);the Major Increase or Decrease Program in The Central Finance Level(grant 2060302);Zhejiang Provincial Key Research&Development Project grants(2017C02011,2018C02030).
Taxus leaves provide the raw industrial materials for taxol,a natural antineoplastic drug widely used in the treatment of various cancers.However,the precise distribution,biosynthesis,and transcriptional regulation of...
funded by the National Key Research and Development Program of China(Grant No.2016YFC0503100);the National Natural Science Foundation of China(Grant Nos.31670429 and 31400346).
Background:Understanding the mechanisms underlying community assembly is helpful for conservation and restoration of communities, particularly those that contain rare and endangered species like Taxus fuana, which are...
This work was supported by National Natural Science Foundation of China(31570675);a Grant from the National Key Research and Development Program of China(2017YFD060070605);a Grant for National non-profit Research Institutions of Chinese Academy of Forestry(CAFYBB2018SY009).
Taxol(Paclitaxel),an important anticancer drug,is derived at very low yields from Taxus(yew)species that grow very slowly.In the present study,thirteen genes that encode enzymes involved in Taxol biosynthesis in Taxus...
A.R.F.and Y.Z.thank the European Union's Horizon 2020 research and innovation program,project Planta SYST(SGA-CSA no.739582 under FPA no.664620)for supporting their research.
Taxaceae is the yew family of conifers and includes evergreen trees and small shrubs mainly distributed in Eurasia and North America.The genus of Taxus has attracted considerable attention since Monroe E.Wall and Mans...
the National Key R&D Program of China(2020YFA0908000);National Science Fund for Excellent Young Scholars(31922047);Tianjin Synthetic Biotechnology Innovation Capacity Improvement Project(No.TSBICIP-KJGG-002);the China Postdoctoral Science Foundation(No.2019M661032)。
Taxus,commonly known as yew,is a well-known gymnosperm with great ornamental and medicinal value.In this study,by assembling a chromosome-level genome of the Himalayan yew(Taxus wallichiana)with 10.9 Gb in 12 chromoso...