YL-1

作品数:351被引量:475H指数:10
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L-Ergothioneine ameliorates 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced Parkinson's disease in C57BL/6J mice by activating DJ-1
《Food Science and Human Wellness》2025年第3期1045-1061,共17页Xianshe Meng Huawen Meng Shuzeng Hou Zequn Yin Xuerui Wang Ke Gong Feng Zhang Qingshan Li Shuang Zhang Yuanli Chen Xiaoxiao Yang Zhiwei Zhao Chenzhong Liao Yajun Duan 
supported by the National Natural Science Foundation of China(U22A20272,82173807,82170497)。
Parkinson's disease(PD)is one of the most common neurodegenerative diseases.The loss of dopaminergic(DAergic)neurons in the substantia nigra and the decrease of dopamine(DA)levels accelerate the process of PD.L-Ergoth...
关键词:L-Ergothioneine 1-Methyl-4-phenyl-1 2 3 6-TETRAHYDROPYRIDINE Parkinson’s disease DJ-1 Dopaminergic neurons 
Genome-wide association analysis reveals regulatory genes for the metabolite synthesis of 2-acetyl-1-pyrroline in aromatic coconut(Cocos nucifera L.)
《Journal of Genetics and Genomics》2025年第2期179-188,共10页Hao Ding Xiang Lv Guangzhen Zhou Xiaomei Liu Xiwei Sun Jing Li Amjad Iqbal Yaodong Yang 
supported by the Major Science and Technology Project of Hainan Province(ZDKJ2021012);National Natural Science Foundation of China(32071805);the National Key Research and Development Program of China(2023YFD2200700)。
Coconut(Cocos nucifera L.)is a key tropical economic tree valued for its fruit flavor,particularly 2-acetyl-1-pyrroline(2AP),a vital aroma metabolite.To enhance high-aromatic coconut breeding efforts,it is essential t...
关键词:Aromatic coconut 2AP SNP Genome-wideassociation study(GWAS) Haplotype analysis 
Multi-omics analysis reveals the neuroprotective effect of Atractylodis Rhizoma Alba extract against Parkinson's disease in mouse
《Journal of Traditional Chinese Medicine》2024年第6期1111-1117,共7页KANG Sohi LEE Soong-In MOON Byeong Cheol SONG Jun Ho KIM Sung-Ho MOON Changjong LEE Sueun KIM Chul KIM Joong Sun 
the Development of Sustainable Application for Standard Herbal Resource by the Korea Institute of Oriental Medicine (No. KSN2012320)。
OBJECTIVE: To assess Atractylodis Rhizoma Alba extract(ARE) neuroprotective function in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine(MPTP)-treated mice and related genes. METHODS: Examined m RNA-DNA methylation change...
关键词:Parkinson disease nerve degeneration 1-methyl-4-phenyl-1 2 3 6-TETRAHYDROPYRIDINE Atractylodis Rhizoma Alba Methyl-seq 
Salinity Stress Deteriorates Grain Yield and Increases 2-Acetyl-1-Pyrroline Content in Rice
《Rice science》2024年第4期371-374,I0015-I0021,共11页WEI Huanhe MA Weiyi ZHANG Xiang ZUO Boyuan GENG Xiaoyu WANG Lulu ZHU Wang CHEN Yinglong HUO Zhongyang XU Ke MENG Tianyao DAI Qigen 
supported by the National Key Research and Development Program, China (Grant Nos. 2022YFE0113400 and 2022YFD1500402);the Key Research and Development Program of Jiangsu Province, China (Grant No. BE2023355);the Natural Science Foundation of the Jiangsu Higher Education Institutions of China (Grant No. 23KJA210004);the Jiangsu Agricultural Science and Technology Innovation Fund, China (Grant No. CX(23)1020);the Scientific and Technological Innovation Fund of Carbon Emissions Peak and Neutrality of Jiangsu Provincial Department of Science and Technology, China (Grant Nos. BE2022304 and BE2022305);the Qinglan Project of Yangzhou University;the Priority Academic Program Development of Jiangsu Higher Education Institutions, China。
Salinity stress greatly impacts rice grain yield and quality, as well as the 2-acetyl-1-pyrroline(2-AP) content in grains. The present study was conducted with Nanjing 9108(NJ9108, conventional japonica rice) and Wenl...
关键词:SALINITY YIELD erior 
Synthesis of 3,5-Diaryl-1,2,4-oxadiazole by One-Pot Homocoupling Reaction
《有机化学》2024年第7期2251-2256,共6页Liu Mengjin Xiao Yan Zhou Kai Li Zicheng Huang Wencai 
3,5-Diaryl-1,2,4-oxadiazoles were synthesized by homocoupling of chloroarylaldoxime from arylaldoxime and N-chlorosuccinimide(NCS)in the presence of Cs_(2)CO_(3) in one pot.The method is suitable for thiophene-3-carba...
关键词:1 2 4-oxadiazole homocoupling reaction ALDEHYDES chlorobenzaldoxime cyclic addition 
Abiotic and Biotic Factors Controlling Grain Aroma along Value Chain of Fragrant Rice:A Review
《Rice science》2024年第2期142-158,共17页Ayut KONGPUN Tonapha PUSADEE Pennapa JAKSOMSAK Kawiporn CHINACHANTA Patcharin TUIWONG Phukjira CHAN-IN Sawika KONSAENG Wasu PATHOM-AREE Suchila UTASEE Benjamaporn WANGKAEW Chanakan PROM-U-THAI 
partially funded by the Chiang Mai University (Grant No. RG25/2566);the Thailand Rice Science Research Hub of Knowledge (NRCT: N34E670027), Thailand
The aroma of fragrant rice is one of the grain quality attributes that significantly influenceconsumer preferences and prices in world markets. The volatile compound 2-acetyl-1-pyrroline (2AP) isrecognized as a key co...
关键词:aromatic rice 2-acetyl-1-pyrroline abiotic stress biotic stress post-harvest management 
Single-neuron neurodegeneration as a degenerative model for Parkinson’s disease被引量:2
《Neural Regeneration Research》2024年第3期529-535,共7页Sandro Huenchuguala Juan Segura-Aguilar 
The positive effect of levodopa in the treatment of Parkinson’s disease,although it is limited in time and has severe side effects,has encouraged the scientific community to look for new drugs that can stop the neuro...
关键词:1-methyl-4-phenyl-1 2 3 6-tetrahydropyridine 6-HYDROXYDOPAMINE aminochrome dopaminergic neurons DT-diaphorase exogenous neurotoxins glutathione transferase M2-2 
Analysis of the Gravity-1 Sea Launch System and Technical Features
《Aerospace China》2024年第1期18-27,共10页ZHANG Tao HUANG Shuai Ma Ma BU Xiangwei XU Guoguang 
Sea launch has the characteristics of flexible launching points, high landing area safety, and good economy. In recent years, it has become one of the important launch methods. Since 2019, China has carried out a tota...
关键词:YL-1 sea launch system technical features 
Sensory Phenotypic and Molecular Identification of Aromatic Rice Accessions Cultivated in Benin
《Advances in Bioscience and Biotechnology》2024年第3期195-206,共12页Chimène Nadège Mahoussi Nanoukon Koffi David Montcho Hambada Deless Edmond Fulgence Thiémélé Bignon Meyrix Pamela Franzel Loumedjinon Babatoundé Franel Carel Wenceslas Affolabi Amed Sèmèvo Havivi Kéllya Laurinzo Déguénon Grâce Finagnon Vitoekpon Arielle Bankole Lambert Gustave Djedatin 
Rice is one of the most widely cultivated cereals in the world, and its aroma is increasingly in demand. With the advancement of research, a major rice flavor gene has been identified on rice chromosome 8. It encodes ...
关键词:Aromatic Rice 2-Acetyl-1-Pyrroline SSR Markers BENIN 
Synthesis of 4-[F-18]Fluoro-4-Deoxy-N-Acetyl-1,3,6-Tri-O-Acetylglucosamine, a Potential Brain Imaging PET Agent
《Natural Science》2024年第3期19-23,共5页Murthy Akula Derek Cressy Lee Collier George Kabalka Dustin Osborne 
The synthesis of a promising brain imaging agent 4-[F-18]fluoro-4-deoxy-N-acetyl-1,3,6-tri-O-acetylglucosamine, 2, was successfully accomplished from commercially available N-acetyl glucosamine in 5 steps. The non-dec...
关键词:N-ACETYLGLUCOSAMINE AMYLOIDOGENESIS Lipase-Candida rugosa 
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