Despite existing curative options like surgical removal,tissue destruction techniques,and liver transplantation for early-stage hepatocellular carcinoma(HCC),the rising incidence and mortality rates of this global hea...
supported by the National Key Research and Development Program(2023YFC2506404);National Natural Science Foundation of China(82372869,82272676,and 82073011);Beijing Municipal Administration of Hospitals’Ascent Plan(DFL20220901,QML20231107);Beijing Natural Science Foundation(7242021).
Neoadjuvant PD-1 inhibitor is promising in cutaneous melanoma but remains unknown in acral melanoma(AM).This phase Ib trial study(Clinicaltrials.gov NCT04197882)assessed the efficacy and safety of the combination of n...
Hepatocellular carcinoma(HCC)is a high mortality neoplasm which usually appears on a cirrhotic liver.The therapeutic arsenal and subsequent prognostic outlook are intrinsically linked to the HCC stage at diagnosis.Not...
Pancreatic ductal adenocarcinoma(PDAC)is still a devastating disease,and for those who treat PDAC patients it sometimes seems that there is little to no relevant progress.The excellent new ESMO clinical practice guide...
The 2023 update of the Chinese Society of Clinical Oncology(CSCO)Clini-cal Guidelines for Gastric Cancer focuses on standardizing cancer diagnosis and treatment in China,reflecting the latest advancements in evidence-...
In the last few decades,the treatment strategy for locally advanced resectable gastric cancer(GC)has shifted to a multimodal approach,which potentially decreases recurrence risk and improves survival rates.Perioperati...
Background:Whether pembrolizumab given both before surgery(neoadjuvant therapy)and after surgery(adjuvant therapy),as compared with pembrolizumab given as adjuvant therapy alone,would increase event-free survival amon...
Immune-checkpoint inhibitors are extensively used in cancer treatment and have transformed the therapeutic landscape by inducing durable responses. Immunotherapy with checkpoint inhibitors targeting programmed death 1...
Patients with early-stage non-small-cell lung cancer(NSCLC)are candidates for curative surgery;however,despite multiple advances in lung cancer management,recurrence rates remain high.Adjuvant chemotherapy has been de...
There exist differences in the epidemiological characteristics,clinicopathological features,tumor biological characteristics,treatment patterns,and drug selections between gastric cancer patients from the Eastern and ...