This work was supported by grants from China State Key Basic Research Program Grants(2016YFA0501403,2016YFA0501404 and 2020YFE0202200);the National Natural Science Foundation of China(31700088);Guangdong Provincial Fund for Distinguished Young Scholars(2019B151502050);Shenzhen Innovation of Science and Technology Commission Grant(JCYJ20170412154126026).
Main observation and conclusion Bioorthogonal click chemistry has emerged as a powerful tool for the specific modification of proteins in complex mixtures.Metabolic labeling of proteins with azide followed by the copp...
supported by Zhejiang Provincial Natural Science Foundation of China(LR19B020001);the National Natural Science Foundation of China(21472162,21772171);the National Basic Research Program of China(2015CB856600)~~
Visible light promoted difunctionalization of alkynes is reviewed. The difunctionalization reaction is achieved by different reagents. Radicals such as carbon(sp3), carbon(sp2), and other heteroatom(P, S, N, Se, O, an...
A convenient method for one-pot two-step 1,3-dipolar cycloadditon reaction of arylboronic acid, sodium azide followed with terminal alkynes in the presence of 2-pyrrolecarbaldiminato-Cu(Ⅱ) complexes catalyst is rep...
supported by the National Natural Science Foundation of China(21490571,21222402,21174120);the Key Project of the Ministry of Science and Technology of China(2013CB834702);the Research Grants Council of Hong Kong(604711,602212,604913);Anjun Qin and Benzhong Tang thank the support from Guangdong Innovative Research Team Program(201101C0105067115)
An air-stable supported Cu(I) catalyst, Cu I@PS-Phen, was designed and synthesized. Cu I@PS-Phen can efficiently catalyze the click polymerization of diynes a and diazides b to produce soluble and thermally stable pol...
supported by the National Basic Research Program of China(2013CB834701);the University Grants Commitee of Hong Kong(Ao E/P-03/08);the National Natural Science Foundation of China(21490570 and 21490574);the Research Grants Council of Hong Kong(16303815;604913 and602212);the Nissan Chemical Industries;Ltd.;and the Innovation and Technology Commission(ITCPD117-9);the support of the Guangdong Innovative Research Team Program(201101C0105067115)
The numerous merits of conjugated polymers(CPs) have encouraged scientists to develop a variety of synthetic routes to CPs with diverse structures and functionalities. Among the large scope of substrates,alkyne plays ...
partially supported by the National Natural Science Foundation of China(Nos.50703033,20974098 and 20974028);the Ministry of Science and Technology of China(2009CB623605);the Research Grants Council of Hong Kong (603509,HKUST2/CRF/10);the University Grants Committee of Hong Kong(AoE/P-03/08)
The great achievements of click chemistry have encouraged polymer scientists to use this reaction in their field. This review assembles an update of the advances of using azide-alkyne click polymerization to prepare f...
Project supported by the National Basic Research Program of China (No. 2009CB825300) and the Natural Science Foundation of China (Nos. 20732005, 20872158).
A Pd(II) catalyzed tandem reaction of o-alkynylbenzaldehydes or o-alkynylbenzaldimines with substituted indoles initiated by the intermolecular addition of indoles to the carbonyl or imine group followed by the nucl...
supported by Tianjin Municipal Science and Technology Commission (09JCYBJC09200);National Key Basic Research and Development Program of China (973 Program, 2007CB914803)
A novel alkynyl substituted N-aryl-1,8-naphthalimide II (C20H11NO2) was synthesized for the discovery and evaluation of new fluorescence probes, and was characterized by X-ray crystal diffraction. It crystallizes in...