AXITINIB

作品数：20被引量：39H指数：4
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相关领域：医药卫生更多>>
相关作者：呼彩莲王翠翠马伯林郭毅戴秋云更多>>
相关机构：延安大学宁夏医科大学苏州大学上海交通大学更多>>
相关期刊：《药学进展》《Acta Pharmacologica Sinica》《宁夏医科大学学报》《Journal of Chinese Pharmaceutical Sciences》更多>>
相关基金：国家自然科学基金宁夏回族自治区自然科学基金更多>>
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Neoadjuvant toripalimab plus axitinib for clear cell renal cell carcinoma with inferior vena cava tumor thrombus:NEOTAX,a phase 2 study被引量：2
《Signal Transduction and Targeted Therapy》2024年第11期5157-5165,共9页Liangyou Gu Cheng Peng Qiyang Liang Qingbo Huang Deqiang Lv Houming Zhao Qi Zhang Yu Zhang Peng Zhang Shichao Li Junnan Xu Luyao Chen Yongpeng Xie Jinhang Li Gang Guo Xu Zhang Baojun Wang Xin Ma 
supported by the National Natural Science Foundation of China(Nos.82373169,82273412,82372704).
The potential benefit of neoadjuvant toripalimab plus axitinib in cases with clear cell renal cell carcinoma(ccRCC)and inferior vena cava tumor thrombus(IVC-TT)remains unclear.NEOTAX was a phase 2 study to investigate...
关键词：THROMBUS unchanged PHASE 
Pembrolizumab combined with axitinib in the treatment of skin metastasis of renal clear cell carcinoma to nasal ala:A case report
《World Journal of Clinical Cases》2023年第9期2104-2109,共6页Shuai Dong Yang-Chun Xu Yuan-Chen Zhang Jian-Xin Xia Yan Mou 
Supported by the National Natural Science Foundation of China,No.81803160.
BACKGROUND Renal clear cell carcinoma(RCC)is a malignant tumor of the genitourinary system with a predilection for males.The most common metastatic sites are the lung,liver,lymph nodes,contralateral kidney or adrenal ...
关键词：Skin metastasis Renal clear cell carcinoma Pembrolizumab AXITINIB Case report 
Chemotherapy,transarterial chemoembolization,and nephrectomy combined treated one giant renal cell carcinoma(T3aN1M1)associated with Xp11.2/TFE3:A case report
《World Journal of Clinical Cases》2022年第28期10180-10185,共6页Peng Wang Xiao Zhang Shuo-Han Shao Fa Wu Fei-Zhou Du Jun-Feng Zhang Zhi-Way Zuo Rui Jiang 
Supported by the Research and Development Program of The General Hospital of Western Theater Command,No.2021-XZYG-C04 and 2021-XZYG-C05。
BACKGROUND Renal cell carcinoma(RCC)with Xp11.2 translocation/TFE3 gene fusion is a rare and distinct subtype of RCC that is classified under tumors with translocation of the microphthalmia-associated transcriptional ...
关键词：Xp11.2/TFE3 Renal Cell Carcinoma TACE AXITINIB Zoledronic Acid Targeted therapy Multimodal imaging Case report 
Clinical outcomes of second-line treatment following first-line VEGFR-TKI failure in patients with metastatic renal cell carcinoma:a comparison of axitinib alone and axitinib plus anti-PD-1 antibody被引量：1
《Cancer Communications》2021年第10期1071-1074,共4页Jiwei Huang Yueming Wang Haoran Zhang Xiaoyi Hu Ping Wang Wen Cai Yichu Yuan Hao Zeng Jin Zhang Wen Kong Yiran Huang Shuo Wang Jianming Guo Qiang Wei Wei Xue 
supported by Shanghai Science and Technology Commission Research Project(21ZR1438900);the Incubating Program for Clinical Research and Innovation of Renji Hospital(PYXJS16-008,PYIII20-07).
Dear editor,The prognosis of metastatic renal cell carcinoma(mRCC)has been significantly improvedwith the development and widespread use of vascular endothelial growth factor(VEGF)pathway inhibitors and mammalian targ...
关键词：METASTATIC treatment prognosis 
Current and emerging therapies for first line treatment of metastatic clear cell renal cell carcinoma被引量：4
《Journal of Cancer Metastasis and Treatment》2021年第1期532-550,共19页Michael T.Serzan Michael B.Atkins 
The therapeutic landscape for advanced clear cell renal cell carcinoma(ccRCC)is rapidly evolving with improved knowledge of the biology of disease leading to the incorporation of a variety of antiangiogenic agents and...
关键词：Renal cell carcinoma nivolumab IPILIMUMAB AXITINIB pembrolizumab avelumab biomarkers 
Antitumor effect of axitinib combined with dopamine and PKPD modeling in the treatment of human breast cancer xenograft被引量：9
《Acta Pharmacologica Sinica》2019年第2期243-256,共14页Yuan-heng Ma Si-yuan Wang Yu-peng Ren Jian Li Ting-jie Guo Wei Lu Tian-yan Zhou 
National Natural Science Foundation of China(Grant No.81473277).
Rising evidence has shown the development of resistance to vascular endothelial growth factor receptor (VEGFR) inhibitors in the practices of cancer therapy. It is reported that the efficacy of axitinib (AX), a VEGFR ...
关键词：Cancer stem-like cell DOPAMINE AXITINIB Combination therapy Pharmacokinetic-pharmacodynamic model 
Comparison of efficacy and safety among axitinib,sunitinib,and sorafenib as neoadjuvant therapy for renal cell carcinoma:a retrospective study被引量：4
《Cancer Communications》2019年第1期510-513,共4页Wen Cai Biao Cai Juan Zhou Yonghui Chen Jin Zhang Yiran Huang Wei Xue Jiwei Huang 
This study was supported by the research project of Shanghai Science and Technology Commission(18ZR1423200);the Incubating Program for Clinical Research and Innovation of Renji Hospital(PYXJS16-008);the Shen Kang 3-year action plan program(16CR3062B)
Dear editor,Renal cancer accounts for approximately 2%of all can-cer deaths worldwide,and renal cell carcinoma(RCC)is the predominant subtype[1].Radiotherapy and chemo-therapy have been found to have limited roles in ...
关键词：RENAL THERAPY treatment 
Axitinib抑制钛颗粒诱导小鼠air pouch组织炎性骨溶解中VEGF表达被引量：2
《宁夏医科大学学报》2018年第12期1375-1379,共5页陈德胜 李燕 郭凤英 张佳林 赵江博 田佳宁 
国家自然科学基金(81760405;81760395;81560364);宁夏自然科学基金重点项目(2018AAC02013);宁夏医科大学校级课题重点项目(XZ2018014);宁夏回族自治区人事厅留学资助基金(2017659)
目的探讨阿帕替尼(Axitinib)减轻磨损颗粒诱导骨溶解的作用及其机制。方法 45只雄性BALB/C小鼠,随机分为对照组、模型组和Axitinib治疗组,每组15只,建立air pouch,模型组和Axitinib治疗组air pouch中注射0.3 mL钛颗粒,对照组air pouch...
关键词：阿帕替尼 小鼠 钛颗粒 骨溶解 血管内皮生长因子 
Safety of axitinib and sorafenib monotherapy for patients with renal cell carcinoma:a meta-analysis被引量：4
《The Journal of Biomedical Research》2018年第1期30-38,共9页Fei Qin Hao Yu Changrong Xu Huihui Chen Jianling Bai 
supported by grants from the National Natural Science Foundation of China (81773554 to H. Yu);the National Natural Science Foundation of China Grant for Young Scientists (81302512 to J. Bai)
We sought to investigate safety of axitinib or sorafenib in renal cell carcinoma（RCC） patients and compare toxicity of these two vascular endothelial growth factor receptor inhibitors. Databases of PubMed and Embase...
关键词：axitinib sorafenib safety renal cell carcinoma meta-analysis 
VEGF抑制剂阿西替尼对人胃癌细胞周期及凋亡的影响被引量：1
《宁夏医学杂志》2017年第6期494-495,I0001,共3页袁春秀 王宁菊 吴婧 
目的研究VEGF抑制剂阿西替尼(Axitinib)对人胃癌细胞AGS细胞周期和凋亡的影响。方法采用流式细胞仪检测0μmol/L、0.1μmol/L、1μmol/L、5μmol/L的阿西替尼作用AGS细胞24 h后对细胞周期的影响;采用同样方法检测该药对AGS细胞凋亡的影...
关键词：胃癌AGS细胞系 AXITINIB 细胞周期 细胞凋亡 
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