AZA

作品数:112被引量:188H指数:7
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相关领域:理学医药卫生更多>>
相关作者:葛畅张玉萍许春伟方园王鲁平更多>>
相关机构:中国科学院华中师范大学兰州大学北京化工大学更多>>
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相关基金:国家自然科学基金国家重点基础研究发展计划湖北省自然科学基金中国博士后科学基金更多>>
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Ven+AZA方案和CAG+AZA方案治疗老年复发难治性急性髓系白血病患者的效果比较
《河南医学研究》2025年第3期496-499,共4页丁辉 陈芳 
目的 比较维奈托克(Ven)+阿扎胞苷(AZA)方案和CAG+AZA方案治疗老年复发难治性急性髓系白血病(AML)患者的效果和不良反应。方法 选取2019年6月至2022年6月在河南大学淮河医院血液内科接受治疗的112例老年复发难治性AML患者,采用抽签分组...
关键词:急性髓系白血病 维奈托克 阿扎胞苷 CAG方案 
N-(苯并噻唑-2-基)亚胺与4-硝基-1-苯基丁-1-酮的aza-Henry/半缩酮胺化串联反应
《北京理工大学学报》2025年第2期205-212,共8页杜大明 郑瑶 
通过对近些年来文献的研究,发现对于使用N-(苯并噻唑-2-基)亚胺作为C2合成子的研究较少,因此探索以N-(苯并噻唑-2-基)亚胺作为C2合成子生成一系列杂环衍生物的新方法具有重要价值.成功设计通过aza-Henry/半缩酮胺化串联反应合成了一系...
关键词:有机合成 串联反应 苯并噻唑 亚胺 4-硝基-1-苯基丁-1-酮 哌啶 
Triple Aza[6]helicenes with Circularly Polarized Luminescence:N-Alkylation as a Tool to Tune the Chiroptical Properties
《有机化学》2024年第9期2841-2846,共6页Xia Yufei Jiang Li Yang Qiao Yu Xiu Chen Fengkun 
国家自然科学基金(No.22171044)资助项目.
Recently,multiple helicenes have attracted enormous attention due to their exceptionally distorted conjugated architectures,appealing optical properties and unique spatial stacking patterns.The electronic and optical ...
关键词:HELICENE multiple heterohelicene chiral resolution circularly polarized luminescence ALKYLATION 
Vonoprazan-amoxicillin dual therapy for Helicobacter pylori eradication in Chinese population:A prospective,multicenter,randomized,two-stage study
《World Journal of Gastroenterology》2024年第27期3304-3313,共10页Xue-Ping Huang Zhi-Hui Lin Yi-Juan Liu Shao-Wei Lin Yan-Feng Shao Feng Qiu Qing-Wu Qiu Zhang-Kun Xu Jin-Xian Chen Liang-Huo Chen Zhen-Qun Lin Wen-Hua Dai Ming-Qing Zhang Qi Jiang Zhong-Qin Xiao Xian-Xing Cheng Xiang-Fei Zhang Wen-Bin You Wei Chen Long-Qin Li Wei-Xing Lin Yong-Fu Wang Fu-Jin Lai Long-Qun Chen Zhong-Hua Huang Wen-Qi Zheng Jin-Qi Wei 
Supported by the Natural Science Foundation of Fujian Province,No.2020J011087 and No.2022J011025;Medical Innovation Project of Fujian Provincial Health Commission,No.2020CXA006;Zhuhai Science and Technology Project,No.20181117E030040.
BACKGROUND The efficacy of Vonoprazan-amoxicillin dual therapy(VAT)in the treatment of Helicobacter pylori(H.pylori)is controversial.AIM To evaluate the efficacy of VAT in the Chinese population.METHODS This prospecti...
关键词:Helicobacter pylori Vonoprazan AMOXICILLIN Dual therapy Bismuth quadruple therapy 
Vonoprazan-amoxicillin dual regimen with Saccharomyces boulardii as a rescue therapy for Helicobacter pylori:Current perspectives and implications被引量:2
《World Journal of Gastroenterology》2024年第10期1280-1286,共7页Valerie Josephine Dirjayanto Jessica Audrey Daniel Martin Simadibrata 
Yu et al’s study in the World Journal of Gastroenterology(2023)introduced a novel regimen of Vonoprazan-amoxicillin dual therapy combined with Saccharomyces boulardii(S.boulardii)for the rescue therapy against Helico...
关键词:Vonoprazan Saccharomyces boulardii Helicobacter pylori Rescue therapy Eradication rate 
Imidazobenzimidazole fused aza-calix[4]arenes:Synthesis,structure,and Zn^(2+)-selective colorimetric-fluorometric sensor
《Chinese Chemical Letters》2023年第12期204-208,共5页Yuan-Tao Huang Min Xue Yong Yang 
supported by National Natural Science Foundation of China(Nos.21971223 and 21772178).
Tetra(amino)azacalix[4]arene skeleton was functionalized at the bridging NH sites using various aromatic aldehydes via formation of imidazobenzimidazole fused heterocycles.X-ray single crystal analysis revealed distor...
关键词:arene Imidazobenzimidazole Fluorometric sensor Zn^(2+)-selective 
Developments and applications of allyl-(aza)allyl coupling reactions
《Green Synthesis and Catalysis》2023年第3期190-205,共16页Leiyang Lv Huijun Qian 
supported by the National Natural Science Foundation of China(No.22201300);the Fundamental Research Funds for the Central Universities,and the Research Funds of Renmin University of China(No.21XNLG04).
We have summarized the developments and advancements of allyl-(aza)allyl coupling reactions in the past years.Since the first report in 1980,Pd-catalyzed allyl-allyl couplings have not drawn chemists'much attention fo...
关键词:ALLYLATION Pd catalysis CROSS-COUPLING C-C bond formation C-X bond formation 
AZA联合HHT和LDAC治疗3+7常规方案不耐受的急性髓系白血病患者的疗效和安全性
《中国医师杂志》2023年第8期1159-1164,共6页林先凤 彭宏凌 王志华 邓泽宇 
国家自然科学基金(82070175)。
目的评估阿扎胞苷(AZA)联合高三尖杉酯碱(HHT)和低剂量阿糖胞苷(LDAC)治疗3+7常规方案不耐受的急性髓系白血病(AML)患者的有效性和安全性。方法回顾性分析中南大学湘雅二医院收治的33例AML患者(15例初治患者和18例复发/难治性患者)的临...
关键词:阿扎胞苷 高三尖杉酯碱 阿糖胞苷 白血病 髓样 急性 
Cp*Rh/Ag catalyzed C–H activation/cyclization sequences of NH-sulfoximines to fused aza-polyheterocycles under gentle conditions
《Green Synthesis and Catalysis》2023年第2期160-168,共9页Jiapian Huang Fei Liu Feihua Du Linghui Zeng Zhiyuan Chen 
the National Natural Science Foundation of China(No.21961015);the Natural Science Foundation of Jiangxi Province(No.20202ACBL203005)for their financial support.
Disclosed herein is a novel Rh/Ag co-catalyzed S=NH directed C–H activation and C–H/N–H bond functionalization protocol of free NH-sulfoximines with hypervalent iodonium ylides.With the aid of AgOTf,these C–H func...
关键词:Rhodium catalysis C-H activation SULFOXIMINE Polyheterocycle CYCLIZATION 
Mesothelin targeted nano-system enhanced chemodynamic therapy and tirapazamine chemotherapy via lactate depletion被引量:1
《Nano Research》2023年第5期7108-7118,共11页Guodong Cao Wei Cao Jiawei Zhang Qing Chen Junjie Chen Qiang Chu Qiang Sun Maoming Xiong Bo Chen Xiang Li 
the mission book of promotion program of basic and clinical collaborative research of Anhui Medical University(No.2022xkjT028);Anhui Provincial Scientific Research Preparation Plan Project(No.2022AH051171);the Anhui Provincial Natural Science Foundation(No.2208085MH240);Postgraduates of Colleges and Universities in Anhui Province(No.YJS20210308);the National Natural Science Foundation of China(No.81602425);the Anhui Quality Engineering Project(Nos.2020jyxm0898,2020jyxm0910,and 2019kfkc334);the Anhui Medical University Clinical Research Project(No.2020xkj176);the Anhui Health Soft Science Research Project(No.2020WR01003);the Key Research and Development Program of Anhui Province(No.201904a07020045).
The enhanced permeability and retention(EPR)effect alone is not enough for nanoparticles to reach the target.Combination of active and passive targeting may be an effective drug delivery route.Hollow ferric-tannic aci...
关键词:MESOTHELIN lactate oxidase tumor metastasis synergetic cancer therapy chemodynamic therapy 
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