SULFOXIMINE

作品数：14被引量：43H指数：3
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相关领域：医药卫生更多>>
相关作者：张宇孙健更多>>
相关机构：中国科学院成都生物研究所中国科学院研究生院更多>>
相关期刊：《Acta Pharmacologica Sinica》《Science China Chemistry》《World Journal of Gastroenterology》《Advances in Parkinson's Disease》更多>>
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Catalytic enantioselective N-silylation of sulfoximine
《Chinese Chemical Letters》2024年第4期352-356,共5页Xingfen Huang Jiefeng Zhu Chuan He 
financial support from the National Natural Science Foundation of China (Nos.22122102, 22101120, 22271134);Guangdong Provincial Key Laboratory of Catalysis (No.2020B121201002);Guangdong Pearl River Talent Program (No.2019QN01Y628);Shenzhen Science and Technology Innovation Committee (No.RCJC20221008092723013);Key Laboratory of Organosilicon Chemistry and Material Technology of Ministry of Education (No.KFJJ2022012)。
A rhodium/diphosphine-catalyzed asymmetric cross-dehydrogenative coupling between sulfoximines and dihydrosilanes has been achieved. This is the first report on the enantioselective N-silylation of sulfoximines. The p...
关键词：N-Silylation of sulfoximine Chiral silylamine Si-stereogenic silanes Si-CADC Asymmetric catalysis 
Discovery of Novel Anthranilic Diamide Derivatives Bearing Sulfoximine Group as Potent Insecticide Candidates
《Chemical Research in Chinese Universities》2024年第1期96-108,共13页ZHANG Hongyuan PENG Jinmin ZHONG Yuanhan CHEN Yue WANG Qing Haditullah HADIATULLAH XIE Weibin XIONG Lixia YUCHI Zhiguang LIU Jingbo LI Yuxin 
Nankai University Cangzhou Bohai New Area Green Chemical Research Institute(NCC)Fund,the National Natural Science Foundation of China(Nos.31972287,32022073);the National Key Research and Development Program of China(No.2022YFE0108400);the Scientific Project of Tianjin Municipal Education Commission,China(No.2022KJ026).
The fall armyworm,Spodoptera frugiperda(S.frugiperda),represents the most resistant insect species and poses serious threat to grain yield.Chlorantraniliprole(CHL),which targets the ryanodine receptors(RyRs)in insects...
关键词：Anthranilic diamide derivative SULFOXIMINE Spodoptera frugiperda Mode of action Molecular docking 
Cp*Rh/Ag catalyzed C–H activation/cyclization sequences of NH-sulfoximines to fused aza-polyheterocycles under gentle conditions
《Green Synthesis and Catalysis》2023年第2期160-168,共9页Jiapian Huang Fei Liu Feihua Du Linghui Zeng Zhiyuan Chen 
the National Natural Science Foundation of China(No.21961015);the Natural Science Foundation of Jiangxi Province(No.20202ACBL203005)for their financial support.
Disclosed herein is a novel Rh/Ag co-catalyzed S=NH directed C–H activation and C–H/N–H bond functionalization protocol of free NH-sulfoximines with hypervalent iodonium ylides.With the aid of AgOTf,these C–H func...
关键词：Rhodium catalysis C-H activation SULFOXIMINE Polyheterocycle CYCLIZATION 
Multipurpose sulfoximine-mediated radicalγ-heteroarylation of unactivated C(sp^(3))–H bonds被引量：1
《Science China Chemistry》2023年第5期1435-1442,共8页Yuqian Sun Xinxin Wu Zhu Cao Chen Zhu 
supported by the National Natural Science Foundation of China(21971173,22001185,22171201);the Natural Science Foundation of Jiangsu Province(BK20200852);the Priority Academic Program Development of Jiangsu Higher Education Institutions(PAPD)。
A conceptually novel,trifunctional sulfoximine-mediatedγ-functionalization of unactivated C(sp^(3))–H bonds has been achieved.The reaction is initiated by the photo-induced homolytic cleavage of an N–S bond in the ...
关键词：SULFOXIMINE hydrogen atom transfer functional group migration C(sp^(3))–H functionalization heteroarylation PHOTOCHEMISTRY 
Reversing ferroptosis resistance by MOFs through regulation intracellular redox homeostasis被引量：3
《Asian Journal of Pharmaceutical Sciences》2023年第1期86-96,共11页Chengcheng Wang JiaoWang Xue Pan Shuang Yu Meiqi Chen Yan Gao Zilin Song Haiyang Hu Xiuli Zhao Dawei Chen Fei Han Mingxi Qiao 
As a non-apoptotic cell death form,ferroptosis offers an alternative approach to overcome cancer chemotherapy resistance.However,accumulating evidence indicates cancer cells can develop ferroptosis resistance by evolv...
关键词：Ferroptosis Buthionine-(S R)-sulfoximine GLUTATHIONE Metal organic framework Photodynamic therapy Immunogenic cell death 
Difluoromethyl 2-Pyridyl Sulfoximine:A Stereoselective Nucleophilic Reagent for Difluoro(aminosulfinyl)methylation and Difluoro(aminosulfonyl)methylation
《CCS Chemistry》2022年第11期3648-3659,共12页Qinghe Liu Chuanfa Ni Qian Wang Depei Meng Jinbo Hu 
Financial support was provided by the National Key Research and Development Program of China(no.2016YFB0101200);the National Natural Science Foundation of China(no.21632009);the Key Programs of CAS(no.KGZD-EW-T08);the Key Research Program of Frontier Sciences of CAS(no.QYZDJ-SSW-SLH049);Shanghai Science and Technology Program(no.16QA1404600).
1,1-Difluorinated sulfonamides are known to have better anti-inflammatory activity and enzyme inhibitory potency than their nonfluorinated counterparts.Two geminal fluorine atoms cause electronic perturbation of the n...
关键词：difluoro(aminosulfonyl)methylation difluoro(aminosulfinyl)methylation STEREOSELECTIVE NUCLEOPHILIC SULFOXIMINE 
Osthole prevents tamoxifen-induced liver injury in mice被引量：7
《Acta Pharmacologica Sinica》2019年第5期608-619,共12页Wen-bo Zhou Xin-xin Zhang Yun Cai Wu Sun Hao Li 
the National Natural Science Foundation of China (No.81270944 and No.81070678).
Tamoxifen (TMX) is an antiestrogen drug that is used in the treatment and prevention of all stages of estrogen-dependent breast cancer. Adverse effects of TMX include hepatotoxicity. In this study, we investigated the...
关键词：hepatotoxicity TAMOXIFEN oxidative stress OSTHOLE MAPK SB203580 L-buthionine SULFOXIMINE N-ACETYL-L-CYSTEINE 
Glutathione depleting drugs, antioxidants and intestinal calcium absorption被引量：7
《World Journal of Gastroenterology》2018年第44期4979-4988,共10页Luciana Moine María Rivoira Gabriela Díaz de Barboza Adriana Pérez Nori Tolosa de Talamoni 
Glutathione （GSH） is a tripeptide that constitutes one of the main intracellular reducing compounds. The normal content of GSH in the intestine is essential to optimize the intestinal Ca2＋ absorption. The use of GS...
关键词：GLUTATHIONE Transcellular and paracellular Ca^2＋pathways DL-buthionine-S R-sulfoximine Fructose rich diet MENADIONE Sodium deoxycholate Glutamine Ursodeoxycholic acid Melatonin Quercetin NARINGIN 
Effect of Alteration of Glutathione Content on Cell Viability in α-Synuclein-Transfected SH-SY5Y Cells
《Advances in Parkinson's Disease》2017年第3期93-100,共8页Ken-Ichi Tanaka Kanako Sonoda Masato Asanuma 
It is well known that α-synuclein (αS) plays an important role in the pathogenesis of Parkinson’s disease (PD). Moreover, oxidative stress is also thought to be an important factor in PD due to induction of dopamin...
关键词：Α-SYNUCLEIN L-Buthionine-SR-Sulfoximine N-ACETYL-L-CYSTEINE GLUTATHIONE SH-SY5Y Cells Parkinson’s Disease 
Oxidative stress, antioxidants and intestinal calcium absorption被引量：24
《World Journal of Gastroenterology》2017年第16期2841-2853,共13页Gabriela Diaz de Barboza Solange Guizzardi Luciana Moine Nori Tolosa de Talamoni 
Supported by Dr.Nori Tolosa de Talamoni from CONICET,No.PIP 2013-2015 and No.SECYT(UNC)2016,Argentina
The disequilibrium between the production of reactive oxygen(ROS) and nitrogen(RNS) species and their elimination by protective mechanisms leads to oxidative stress. Mitochondria are the main source of ROS as by-produ...
关键词：Transcellular and paracellular Ca2+pathways DL-buthionine-S R-sulfoximine MENADIONE Sodium deoxycholate Lithocholic acid Ursodeoxycholic acid MELATONIN 
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