CAVEOLAE

作品数:82被引量:287H指数:9
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相关领域:医药卫生更多>>
相关作者:廖端芳秦旭平刘彦梅暴军香谌赟更多>>
相关机构:南华大学北京大学第三军医大学中山大学更多>>
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相关基金:国家自然科学基金国家重点基础研究发展计划湖南省自然科学基金国家高技术研究发展计划更多>>
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Regulation of cellular senescence by the essential caveolar component PTRF/Cavin-1被引量:5
《Cell Research》2011年第7期1088-1101,共14页Lin Bai Xiaoli Deng Juanjuan Li Miao Wang Qian Li Wei An Deli A Yu-Sheng Cong 
thank Dr Silvia Bacchetti for critical reading of the manuscript, Dr Pingsheng Liu for providing the caveolin-I siRNA and helpful discussions. This work was supported in part by a grant from the National Natural Science Foundation of China (30671065) and grants from the National Basic Research Program of China (973 Program) (2007CB507402, 2007CB914402).
Polymerase I and transcript release factor (PTRF, also known as Cavin-l) is an essential component in the biogenesis and function of caveolae. Here, we show that PTRF expression is increased in senescent human fibro...
关键词:PTRF CAVEOLAE caveolin- 1 cellular senescence 
Caveolae and caveolin-1 mediate endocytosis and transcytosis of oxidized low density lipoprotein in endothelial cells被引量:9
《Acta Pharmacologica Sinica》2010年第10期1336-1342,共7页Shao-wei SUN Xu-yu ZU Qin-hui TUO Lin-xi CHEN Xiao-yong LEI Kai LI Chao-ke TANG Duan-fang LIAO 
Aim: To explore the mechanisms involved in ox-LDL transcytosis across endothelial cells and the role of caveolae in this process. Methods: An in vitro model was established to investigate the passage of oxidized low...
关键词:CAVEOLAE CAVEOLIN-1 oxidized low density lipoprotein atherosclerosis TRANSCYTOSIS human umbilical vein endothelial cells 
A Second Protein Marker of Caveolae:Caveolin-2被引量:6
《Chinese Medical Sciences Journal》2010年第2期119-124,共6页Liu-luan Zhu Ying Cui Yong-sheng Chang Fu-de Fang 
Supported by National Basic Research Program of China (973 Program) (2004CB518602,2006CB503909);National High Technology Research and Development Program of China (863 Program) (2009AA02Z192)
Caveolin-2,a protein about 20 kD,is a major component of the inner surface of caveolae,small invaginations of the plasma membrane.Similar with caveolin-1 and caveolin-3,it serves as a protein marker of caveolae.Caveol...
关键词:caveolin-2 LUNG lipid metabolism CANCER 
Caveolin-1、Caveolae和动脉粥样硬化被引量:1
《国际内科学杂志》2009年第9期509-511,531,共4页刘定辉 钱孝贤 
国家重点基础研究发展计划("973"计划;2005CB523305);广东省自然科学基金资助课题(8151008901000209);广东省科技计划项目资助课题(2007B060401024)
Caveolae是细胞表面直径为50~100nm的胞膜穴样内陷,主要由胆固醇、糖基鞘磷脂、鞘磷脂和一些结构蛋白如Caveolin组成。Caveolin-1是Caveolae的主要组成成分,它与细胞骨架蛋白间接偶联来维持Caveolae的内陷形态。Caveolae和Caveolin-1...
关键词:动脉粥样硬化 CAVEOLAE CAVEOLIN-1 
Caveolin与中枢神经系统疾病被引量:1
《神经疾病与精神卫生》2008年第3期165-169,共5页周靖 董文敏 王丽娜 崔德华 
国家自然基金(项目号30570553;30670414);科技部973项目(2006CB500705);北大医学部基础学院创新人才项目资助
关键词:CAVEOLIN 中枢神经系统疾病 CAVEOLAE CAVEOLIN 酰基鞘氨醇 介导细胞 胆固醇 
Glut-4 is translocated to both caveolae and non-caveolar lipid rafts, but is partially internalized through caveolae in insulin-stimulated adipocytes被引量:6
《Cell Research》2007年第9期772-782,共11页Taichang Yuan 
Caveolae and non-caveolar lipid rafts are two types of membrane lipid microdomains that play important roles in insulin-stimulated glucose uptake in adipocytes. In order to ascertain their specific functions in this p...
关键词:Glut-4 translocation Glut-4 internalization lipid rafts CAVEOLAE sucrose density gradient flotation 
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