thank Dr Silvia Bacchetti for critical reading of the manuscript, Dr Pingsheng Liu for providing the caveolin-I siRNA and helpful discussions. This work was supported in part by a grant from the National Natural Science Foundation of China (30671065) and grants from the National Basic Research Program of China (973 Program) (2007CB507402, 2007CB914402).
Polymerase I and transcript release factor (PTRF, also known as Cavin-l) is an essential component in the biogenesis and function of caveolae. Here, we show that PTRF expression is increased in senescent human fibro...
Aim: To explore the mechanisms involved in ox-LDL transcytosis across endothelial cells and the role of caveolae in this process. Methods: An in vitro model was established to investigate the passage of oxidized low...
Supported by National Basic Research Program of China (973 Program) (2004CB518602,2006CB503909);National High Technology Research and Development Program of China (863 Program) (2009AA02Z192)
Caveolin-2,a protein about 20 kD,is a major component of the inner surface of caveolae,small invaginations of the plasma membrane.Similar with caveolin-1 and caveolin-3,it serves as a protein marker of caveolae.Caveol...
Caveolae and non-caveolar lipid rafts are two types of membrane lipid microdomains that play important roles in insulin-stimulated glucose uptake in adipocytes. In order to ascertain their specific functions in this p...