TRANSCYTOSIS

作品数：28被引量：97H指数：7
导出分析报告
相关领域：医药卫生生物学更多>>
相关机构：浙江大学更多>>
相关期刊：《Acta Pharmacologica Sinica》《World Journal of Gastroenterology》《Science Bulletin》《Research》更多>>
相关基金：国家自然科学基金高等学校学科创新引智计划国家重点基础研究发展计划中国博士后科学基金更多>>
-
在结果中检索

检索结果分析

结果分析中...
共 条 记 录，以下是1-10
全选清除导出
参考文献引证文献引用追踪
视图：
排序：
Interaction of major facilitator superfamily domain containing 2A with the blood-brain barrier
《Neural Regeneration Research》2025年第8期2133-2152,共20页Yilun Ma Taiwei Dong Fei Luan Juanjuan Yang Feng Miao Peifeng Wei 
supported by the National Natural Science Foundation of China,No.82104412(to TD);Shaanxi Provincial Key R&D Program,No.2023-YBSF-165(to TD);the Natural Science Foundation of Shaanxi Department of Science and Technology,No.2018JM7022(to FM);Shaanxi Provincial Key Industry Chain Project,No.2021ZDLSF04-11(to PW)。
The functional and structural integrity of the blood-brain barrier is crucial in maintaining homeostasis in the brain microenvironment;however,the molecular mechanisms underlying the formation and function of the bloo...
关键词：blood-brain barrier(BBB) caveolin-1 central nervous system docosahexaenoic acid endothelial cells LYSOPHOSPHATIDYLCHOLINE major facilitator superfamily domain containing 2A(MFSD2A) TRANSCYTOSIS 
Ferritin nanocage loading lycopene for improving blood-brain barrier transcytosis and attenuating D-galactose-induced apoptosis in PC12 cells
《Food Science and Human Wellness》2025年第3期880-891,共12页Xiaoyu Xia Han Li Xianbing Xu Zhenyu Wang Junjie Yi Guanghua Zhao Ming Du 
financially supported by the National Natural Science Foundation of China(31730069);Graduate Innovation Fund of Dalian Polytechnic University。
Aging is a physiological process that leads to degeneration and functional decline of the brain.This is accompanied by intracellular peroxidation and neuronal apoptosis.Natural antioxidants possess a remarkable effect...
关键词：FERRITIN LYCOPENE NANOCARRIER Neuroprotection Aging 
Enhanced transcytosis and retention(ETR)effect
《Science Bulletin》2024年第23期3640-3643,共4页Mengmeng Qin Zhenhan Feng Huan Meng 
supported by National Key Research and Development Program of China(2021YFA1200902 and 2022YFA1207300);the National Natural Science Foundation of China(82204300 and 32271452);Basic Science Center Project of the National Natural Science Foundation of China(22388101);CAS Project for Young Scientists in Basic Research(YSBR-036).
The enhanced permeability and retention(EPR)effect,first proposed by Maeda and co-workers[1]in 1986,has been considered as a classic principle for decades in the field of nano drug delivery for oncology.This theory,th...
关键词：RETENTION EFFECT thereby 
Blood-brain barrier pathology in cerebral small vessel disease被引量：6
《Neural Regeneration Research》2024年第6期1233-1240,共8页Ruxue Jia Gemma Solé-Guardia Amanda J.Kiliaan 
supported by China Scholarship Council(202208210093,to RJ)。
Cerebral small vessel disease is a neurological disease that affects the brain microvasculature and which is commonly observed among the elderly.Although at first it was considered innocuous,small vessel disease is no...
关键词：blood-brain barrier dysfunction cerebral blood flow cerebral hypoperfusion endothelial dysfunction HYPERTENSION inflammation magnetic resonance imaging neurovascular unit oxidative stress small vessel disease tight junctions TRANSCYTOSIS 
Orange-derived extracellular vesicles nanodrugs for efficient treatment of ovarian cancer assisted by transcytosis effect被引量：1
《Acta Pharmaceutica Sinica B》2023年第12期5121-5134,共14页Feng Long Yao Pan Jinheng Li Suinan Sha Xiubo Shi Haoyan Guo Chuanqing Huang Qian Xiao Chao Fan Xingmei Zhang Jun-Bing Fan Ying Wang 
supported by the National Natural Science Foundation of China(22275080,22075127,and 82073340);the Natural Science Foundation of Guangdong Province(2022A 1515012044,China).
Extracellular vesicles(EVs)have recently received much attention about the application of drug carriers due to their desirable properties such as nano-size,biocompatibility,and high stability.Herein,we demonstrate ora...
关键词：Extracellular vesicles TRANSCYTOSIS Cancer treatment Drug delivery system Targeted modification Receptor-mediated endocytosis Intracellular trafficking Recycling endosome 
Light-activated arginine-rich peptide-modified nanoparticles for deep-penetrating chemo-photo-immunotherapy of solid tumor
《Nano Research》2023年第7期9804-9814,共11页Yonghua Gong Jinyang Zhang Yan Lu Dong Wan Jie Pan Guilei Ma 
We acknowledge financial support from National Natural Science Foundation of China(Nos.82172089,22178270 and 22078246);the Fundamental Research Funds for the Central Universities(No.2019PT320028);CAMS Innovation Fund for Medical Sciences(No.2021-I2M-1-058).
Poor permeation of drugs and“immune-cold”tumor microenvironment in solid tumors are the two major challenges which lead to the inefficient therapeutic efficacy for cancer treatment.Here,light-activated penetrable na...
关键词：light-activated nanoparticles TRANSCYTOSIS deep penetration chemo-photo-immunotherapy solid tumor 
Hybrid transcytosis nanopomegranates for sensitizing breast cancer radiotherapy in deep tumor tissue
《Nano Research》2023年第5期7260-7268,共9页Li Wang Liang Xiao Zhengyang Zhao Kai Zhong Weiliang Zhu Hao Liu Xiaoqiu Li 
the National Natural Science Foundation of China(Nos.32101139 and 81901888);the Fundamental Research Fund for the Central Universities(No.WK9100000006);the China Postdoctoral Science Foundation(No.2020M683160);the Guangdong Basic and Applied Basic Research Foundation(No.2021A1515220028);the Natural Science Foundation of Anhui Province of China(No.1908085MH247);the University of Science and Technology of China Animal Care and Use Committee(No.USTCACUC1801062).
As a standard cancer treatment method,radiotherapy(RT)has cured or alleviated over half cancer bearing patients worldwide more than 100 years.However,the therapeutic outcome is seriously hindered by the resistant tumo...
关键词：breast cancer TRANSCYTOSIS hybrid nanopomegranate hypoxia alleviation RADIOSENSITIZATION 
“One-for-All”approach:a black technology for nanomedicine development?
《Medical Review》2023年第2期184-187,共4页Jiajia Xiang Shiqun Shao Zhuxian Zhou Youqing Shen 
supported by the National Key Research and Development Program(2021YFA1201200);the National Natural Science Foundation of China(51833008 and 52203193);the Zhejiang Provincial Key Research and Development Program(2020C01123).
Cancer nanomedicines require different,even opposite,properties to voyage the cascade drug delivery process involving a series of biological barriers.Currentlyapproved nanomedicines can only alleviate adverse effects ...
关键词：cell membrane affinity clinical translation NANOMEDICINE One-for-All TRANSCYTOSIS 
Porphyromonas gingivalis bacteremia increases the permeability of the blood-brain barrier via the Mfsd2a/Caveolin-1 mediated transcytosis pathway被引量：10
《International Journal of Oral Science》2023年第1期136-147,共12页Shuang Lei Jian Li Jingjun Yu Fulong Li Yaping Pan Xu Chen Chunliang Ma Weidong Zhao Xiaolin Tang 
supported by Scientific Research Funding Project of Education Department of Liaoning Province [grant number LJKZ0782];National Natural Science Foundation of China [grant numbers 81670999]。
Bacteremia induced by periodontal infection is an important factor for periodontitis to threaten general health. P. gingivalis DNA/virulence factors have been found in the brain tissues from patients with Alzheimer’s...
关键词：gingivalis expression inhibited 
The relationship between amyloid-beta and brain capillary endothelial cells in Alzheimer's disease被引量：14
《Neural Regeneration Research》2022年第11期2355-2363,共9页Yan-Li Zhang Juan Wang Zhi-Na Zhang Qiang Su Jun-Hong Guo 
Shanxi Provincial Special Fund for the Transformation of Scientific and Technological Achievements,No.201704D13111584(to JHG)。
Neurovascular dysfunction,as an integral part of Alzheimer's disease,may have an important influence on the onset and progression of chronic neurodegenerative processes.The bloodbrain barrier(BBB)pathway is one of the...
关键词：Alzheimer's disease amyloid beta Aβclearance blood-brain barrier cerebral amyloid angiopathy DEMENTIA endothelial cells oxidative stress review THERAPEUTICS TRANSCYTOSIS 
全选清除导出
共3页<123>
检索报告 对象比较 聚类工具 使用帮助 返回顶部