supported by the Science and Technology Commission of Shanghai Municipality (20S11902600);the National Natural Science Foundation of China (82172615);the PDH-SPFDU Joint Research Fund (RHJJ2018-05)
Clinically,arsenic trioxide(ATO)was applied to the treatment of acute promyelocytic leukemia(APL)as a reliable and effective frontline drug.However,the administration regimen of AsⅢwas limited due to its fast clearan...