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CHROMOSOME: 作品数：645被引量：1467H指数：18; 导出分析报告; 相关作者：陈孝辛志勇刘宝卜文俊张虎芳更多>>; 相关机构：中国农业科学院作物育种栽培研究所中国科学院复旦大学上海交通大学更多>>; 相关期刊：更多>>; 相关基金：国家自然科学基金国家重点基础研究发展计划国家高技术研究发展计划中国博士后科学基金更多>>

Effects and mechanism of adenovirus-mediated phosphatase and tension homologue deleted on chromosome ten gene on collagen deposition in rat liver fibrosis被引量：4: 《World Journal of Gastroenterology》2017年第32期5904-5912,共9页Shu-rui Xie Jun-yan An Li-bo Zheng Xiao-Xia Huo Jian Guo David Shih Xiao-Lan Zhang; Supported by the National Natural Science Foundation of China,No.30872513; AIM To evaluate the effects of phosphatase and tension homologue deleted on chromosome ten(PTEN) gene on collagen metabolism in hepatic fibrosis and the underlying mechanisms.METHODS rat primary hepatic stellate cells...; 关键词：Collagen metabolism Hepatic stellate cells Phosphatase and tension homologue deleted on chromosome ten PTEN Gene therapy Hepatic fibrosis

Colorectal cancer tumour markers and biomarkers:Recenttherapeutic advances被引量：43: 《World Journal of Gastroenterology》2016年第5期1745-1755,共11页Gustaw Lech Robert Słotwiński Maciej Słodkowski Ireneusz Wojciech Krasnodębski; Colorectal cancer(CRC) is the second most commonly diagnosed cancer among females and third among males worldwide. It also contributes significantly to cancer-related deaths, despite the continuous progress in diagnos...; 关键词：colorectal cancer biomarker microsatelliteinstability KRAS MUTATION BRAF MUTATION PIK3CAmutation CHROMOSOME 18q loss of HETEROZYGOSITY antiepidermalgrowth factor receptor therapy COLORECTALCANCER biomarkers Carcinoembryonic ANTIGEN

Increased susceptibility of aging gastric mucosa to injury:The mechanisms and clinical implications被引量：20: 《World Journal of Gastroenterology》2014年第16期4467-4482,共16页Andrzej S Tarnawski Amrita Ahluwalia Michael K Jones; Supported by VA Merit Review grant to Tarnawski AS; This review updates the current views on aging gastric mucosa and the mechanisms of its increased susceptibility to injury. Experimental and clinical studies indicate that gastric mucosa of aging individuals-“...; 关键词：Aging gastric mucosa INJURY Phosphatase and tensin homologue deleted on chromosome ten-PTEN Survivin Apoptosis HYPOXIA

Aggressive juvenile polyposis in children with chromosome 10q23 deletion被引量：4: 《World Journal of Gastroenterology》2013年第14期2286-2292,共7页Seth Septer Lei Zhang Caitlin E Lawson Jose Cocjin Thomas Attard Holly H Ardinger; Juvenile polyps are relatively common findings in children,while juvenile polyposis syndrome(JPS) is a rare hereditary syndrome entailing an increased risk of colorectal cancer.Mutations in BMPR1A or SMAD4 are found i...; 关键词：POLYPOSIS GENETICS Cancer Endoscopy PEDIATRIC

Tumor suppress genes screening analysis on 4q in sporadic colorectal carcinoma被引量：1: 《World Journal of Gastroenterology》2008年第36期5606-5611,共6页Li-Xin Jiang Jie Xu Zhao-Wen Wang Da-Peng Li Zhi-Hai Peng Jian-Jun Gao Lin He Hai-Tao Zheng; The National Natural Science Foundation of China, No. 30080016 and No. 30470977; AIM: To search candidate tumor suppressor genes (TSGs) on chromosome 4q through detecting high loss of heterozygosity (LOH) regions in sporadic colorectal carcinoma in Chinese patients. METHODS: Thirteen fluorescent l...; 关键词：Loss of heterozygosity Colorectal carcinoma Chromosome 4q Tumor suppressor gene

Genome-wide differences in hepatitis C-vs alcoholism-associated hepatocellular carcinoma被引量：1: 《World Journal of Gastroenterology》2008年第11期1749-1758,共10页Céline Derambure Cédric Coulouarn Frédérique Caillot Romain Daveau Martine Hiron Michel Scotte Arnaud Franois Celia Duclos Odile Goria Marie Gueudin Catherine Cavard Benoit Terris Maryvonne Daveau Jean-Philippe Salier; Grants from ANRS,ARC,IREB and ConseilRégional de Haute-Normandie to JPS; AIM:To look at a comprehensive picture of etiology- dependent gene abnormalities in hepatocellular carcinoma in Western Europe. METHODS:With a liver-oriented microarray,transcript levels were compared in nodules and c...; 关键词：ALCOHOLISM CHROMOSOME CIRRHOSIS Hepatitis C TRANSCRIPTOMES Protein function

Are there tumor suppressor genes on chromosome 4p in sporadic colorectal carcinoma?: 《World Journal of Gastroenterology》2008年第1期90-94,共5页Hai-Tao Zheng Li-Xin Jiang Zhong-Chuan Lv Da-Peng Li Chong-Zhi Zhou Jian-Jun Gao Lin He Zhi-Hai Peng; Supported by The National Natural Science Foundation of China, No. 30080016 and No. 30470977; AIM: To study the candidate tumor suppressor genes (TSG) on chromosome 4p by detecting the high frequency of loss of heterozygosity (LOH) in sporadic colorectal carcinoma in Chinese patients.METHODS: Seven fluorescent...; 关键词：Loss of heterozygosity Colorectal carcinoma Chromosome 4p Tumor suppressor gene

Expression of phosphatase and tensin homolog deleted on chromosome ten in liver of athymic mice with hepatocellular carcinoma and the effect of Fuzheng Jiedu Decoction被引量：10: 《World Journal of Gastroenterology》2008年第1期108-113,共6页Li-Rong Yin Ze-Xiong Chen Shi-Jun Zhang Bao-Guo Sun Yong-Dong Liu Hong-Zhong Huang; Supported by the Technological Planning Program of Guangdong Province China, No. 2005B33001040 ;Programs of Bureau of Traditional Chinese Medicine of Guangdong Province, No. 1040056 and 301014; AIM： To explore the expression of phosphatase and tensin homolog deleted on chromosome ten （PTEN） in liver of athymic mice with hepatocellular carcinoma （HCC） and the effect of Fuzheng Jiedu Decoction （FJD）. ME...; 关键词：Phosphatase and tensin homolog deletedon chromosome ten Athymic mice Hepatocellularcarcinoma Fuzheng Jiedu Decoction

Genetics of hepatocellular carcinoma被引量：22: 《World Journal of Gastroenterology》2007年第16期2271-2282,共12页Andreas Teufel Frank Staib Stephan Kanzler Arndt Weinmann Henning Schulze-Bergkamen Peter R Galle; The completely assembled human genome has made it possible for modern medicine to step into an era rich in genetic information and high-throughput genomic analysis. These novel and readily available genetic resources ...; 关键词：Hepatocellular carcinoma Liver cancer GENETICS GENOMICS CHROMOSOME MUTATION Pathway

Frequent loss of heterozygosity in two distinct regions,8p23.1 and 8p22, in hepatocellular carcinoma被引量：12: 《World Journal of Gastroenterology》2007年第7期1090-1097,共8页Tomoe Lu Hiroshi Hano Keisuke Nagatsuma Satoru Chiba Masahiro Ikegami; Supported by The Jikei University Research Fund; AIM： To identify the precise location of putative tumor suppressor genes （TSGs） on the short arm of chromosome 8 in patients with hepatocellular carcinoma （HCC）. METHODS： We used 16 microsatellite markers inform...; 关键词：Loss of heterozygosity CHROMOSOME HEPATOCARCINOGENESIS Hepatocellular carcinoma 8p

CHROMOSOME