T.G.C.is supported by the American Association for the Study of Liver Diseases(AASLD)Clinical,Translational and Outcomes Research Award(CTORA)and National Institute on Alcohol Abuse and Alcoholism(NIAAA)K23AA031310 grant;Research reported in this publication was supported by the NIAAA of the National Institutes of Health(NIH)under Award Number K23AA031310;The content is solely the responsibility of the authors and does not necessarily represent the official views of the NIH.M.C.M.is supported by a grant from the National Institute on Alcohol Abuse and Alcoholism U01 AA026975;consults for GlaxoSmithKline,Amygdala NeProdigy,HepaTX,and Parvus;T.A.K.is supported by U01 AA026975 and has a research relationship with GSK and consults for Alexion.
Alcohol-associated liver disease(ALD)is a significant global health challenge,encompassing a spectrum from steatotic liver disease to cirrhosis and alcohol-associated hepatitis,and contributed to 25%of global cirrhosi...
supported by the Project of the Jilin Science and Technology Development Program[20220401085YY].
Hepatic fibrosis,a degenerative liver lesion,significantly contributes to the deterioration and mortality among patients with chronic liver diseases.The condition arises from various factors including toxins,such as a...
Cirrhosis with complications of liver decompensation and hepatocellular carcinoma(HCC)constitute a leading cause of morbidity and mortality worldwide.Portal hypertension is central to the progression of liver disease ...
Chronic liver disease(CLD)is a significant contributor to global mortality.For people who are living with CLD,however,there is a substantial and often overlooked burden of physical and psychological symptoms that sign...
Portal hypertension-related complications increase mortality in patients,irrespective of its etiology.Classically,endoscopic ultrasound(EUS)was used to assess the portal venous system and collaterals,considering size ...
This is a correction to:Marco Biolato,Federica Vitale,Giuseppe Marrone,Luca Miele,Antonio Grieco,Two elective invasive procedures after a single avatrombopag treatment in a patient with liver cirrhosis and severe thro...
This is a correction to:Yutao Yang,Hao Chen,Min Ji,Jianzhang Wu,Xiaoshan Chen,Fenglin Liu,Shengxiang Rao,A new radiomics approach combining the tumor and peri-tumor regions to predict lymph node metastasis and prognos...
Introduction Severe thrombocytopenia(platelet count<50×10^(9)/L)occurs in 1%–2%of patients with liver cirrhosis and is associated with an increased risk of bleeding[1].In this clinical setting,there is no definite a...
Background:Obesity is commonly observed in patients with cirrhosis,especially with the increasing prevalence of nonalcoholic steatohepatitis(NASH).Bariatric surgery has been avoided in these patients given concerns ab...
the National Institutes of Health through the Michigan Institute for Clinical and Health Research[KL2TR002241]and NIDDK[1K23DK117055-01A1].
Background:Ascites is a costly,morbid complication of cirrhosis.Although a low-sodium diet is central to the clinical management of ascites,its efficacy is limited by poor adherence.We aimed to determine the feasibili...