supported by the National Nature Science Foundation of China (No.82273441,81874065);the National Basic Research Program of China (No.2020YFA0710700);the Knowledge Innovation Program of Wuhan-Shuguang Project (China) (No.2022020801020456);Tongji Hospital (HUST)Foundation for Excellent Young Scientist (China) (No.2020YQ05);the First Level of the Public Health Youth Top Talent Project of Hubei Province (China) (No.2022SCZ051).
Despite the improvement of programmatic screening,adjuvant chemotherapy,and curative resection,colon cancer,with increasing incidence and mortality rates,still poses a significant public health challenge as the third ...
National Key Research and Development Program of China(2023YFC3403800);National Natural Science Foundation of China(81972311,82303782);special Funds of the National Natural Science Foundation of China(82141127);CAMS Innovation Fund for Medical Sciences(CIFMS)(2021-12M-066);Non-profit Central Research Institution Fund of Chinese Academy of Medical Science(2019PT310026);Sanming Project of Medicine in Shenzhen(SZSM202011010).
Liver metastasis remains the primary cause of mortality in patients with colon cancer. Identifying specific driver gene mutations that contribute to metastasis may offer viable therapeutic targets. To explore clonal e...
supported by the grant from the National Natural Science Foundation of China(No.81972322).
To the Editor:Long non-coding RNAs(lncRNAs)are a class of RNA molecules comprising more than 200 nucleotides in length,which possess negligible ability to encode functional proteins.LncRNAs are involved in several cel...
Following the publication,concerns have been raised about a number of figures in this article.The transwell invasion assays shown in Fig.2A were strikingly similar to data appearing in different form in other articles...
Introduction: Colon cancer is often diagnosed late in our context and there is a high prevalence of complicated forms, this including perforation. The optimal surgical treatment remains controversial. The aim of this ...
Objective To evaluate the reliability and validity of Chinese Medicine Symptom Scale (CMss),and to observe the improvement of CM symptoms severity in colon cancer patients during adjuvant chemotherapy by Jianpi Bushen...
This study is supported by National Natural Science Foundation of China(82374320,82060864).
Colon cancer(CRC)is one of the most common malignancies globally,ranking third in terms of new cancer cases and second as a cause of cancer deaths[1].In recent 30 years,the incidence and mortality rates of CRC in Chin...
Colorectal cancer(CRC)screening is a fundamental tool in the prevention and early detection of one of the most prevalent and lethal cancers.Over the years,screening,particularly in those settings where it is well orga...
supported by the National Key R&D Program of China(grant No.2019YFB1309703).
Oral colonic nano-drug delivery system has attracted growing attention in treating colon cancer for their excellent characteristics.However,the unique and complex structure of the gastrointestinal tract is still an ob...
German Research Foundation.Grant Numbers:FOR2438,280163318;DFGSFB/TRR241,375876048;DFGSTU238/10-1,437201724;DFGTRR305,429280966;DFG-NOTICE,493624887 Interdisciplinary Center for Clinical Research Programm zur Förderung von Corona-Forschungsprojekten W.Lutz Stiftung Forschungsstiftung Medizin am Universitätsklinikum Erlangen German Federal Ministry of Education and Research.Grant Numbers:01KT1801,031L0262C Chinese scholarship program。
Dear Editor,Tumor microenvironment(TME)-dependent stromal cell plasticity governs tumor development and therapy response.Tumor endothelial cells(TECs)are a major cellular component in this context[1].In colorectal car...