supported by the National Natural Science Foundation of China(No.82072655);the Scientific and technological innovation team of Shaanxi Innovation Capability Support Plan(China)(No.2023-CX-TD-67);the Key R&D Plan of Shaanxi Province,China(No.2022SF-603).
SPP1^(+) macrophages have been identified as key players in the colorectal cancer(CRC) tumor microenvironment, but their function remains unclear. This study integrated single-cell and spatial transcriptomics with bul...
Supported by National High Level Hospital Clinical Research Funding,No.2023-NHLHCRF-YXHZ-ZRMS-06.
BACKGROUND Previous research yielded conflicting results regarding the association between prediabetes and colorectal cancer(CRC).AIM To systematically assess the incidence of CRC in individuals with prediabetes compa...
Colorectal cancer(CRC)is one of the most common malignancies.In recent years,despite the widespread application of new endoscopic techniques and continuous advancements in treatment methods that have improved the earl...
The study was reviewed and approved by institutional ethics board of Affiliated Hospital of Hebei Engineering University(No.:2024[K]005-01).
BACKGROUND Colon cancer represents a significant malignant neoplasm within the digestive system,characterized by a high incidence rate and substantial disease burden.The F-box protein 22(FBXO22)plays a role in forming...
Supported by Shanghai Municipal Health Commission Research Project,No.202340156.
BACKGROUND Recently,numerous studies have reported the application of nanomedicines in colorectal cancer treatment.However,no systematic bibliometric analysis has been conducted to examine the potential and mechanisms...
BACKGROUND Tumor deposits(TDs)are an independent predictor of poor prognosis in colorec-tal cancer(CRC)patients.Enhanced follow-up and treatment monitoring for TD+patients may improve survival rates and quality of lif...
The study by Wu et al analyzed the correlation between nutritional and inflam-matory markers and prognosis in patients with colorectal cancer peritoneal metastasis.The authors propose the neutrophil-to-lymphocyte rati...
Supported by The Natural Science Foundation of Nanjing University of Chinese Medicine,No.XZR2021019;The Outstanding Young Doctor Program of Jiangsu Province of Chinese Medicine,No.2023QB0140;Project of National Clinical Research Base of Traditional Chinese Medicine in Jiangsu Province,No.JD2022SZ18;The Natural Science Foundation of Nanjing University of Chinese Medicine,No.KYCX21_1710.
BACKGROUND Heart rate variability(HRV)represents efferent vagus nerve activity,which is suggested to be related to fundamental mechanisms of tumorigenesis and to be a predictor of prognosis in various cancers.Therefor...
Despite advances in surgery,chemotherapy,and radiotherapy,the treatment of colorectal cancer(CRC)requires more personalized approaches based on tumor biology and molecular profiling.While some relevant mutations have ...
In this article,we provide an important commentary on the original study Lu et al,which offers insight into the surgical efficacy of transanal total mesorectal excision(TaTME)vs laparoscopic total mesorectal excision(...