COLORECTAL_CANCER

作品数:2128被引量:8407H指数:34
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相关作者:王书奎马中华李娟彭鹏周晶更多>>
相关机构:江苏省人民医院重庆医科大学南方医科大学南方医院中山大学更多>>
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相关基金:国家自然科学基金广东省自然科学基金中国博士后科学基金国家重点基础研究发展计划更多>>
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SPP1þmacrophages in colorectal cancer:Markers of malignancy and promising therapeutic targets
《Genes & Diseases》2025年第3期428-446,共19页Zhenyu Xie Gaozan Zheng Liaoran Niu Kunli Du Ruikai Li Hanjun Dan Lili Duan Hongze Wu Guangming Ren Xinyu Dou Songchen Dai Fan Feng Jian Zhang Jianyong Zheng 
supported by the National Natural Science Foundation of China(No.82072655);the Scientific and technological innovation team of Shaanxi Innovation Capability Support Plan(China)(No.2023-CX-TD-67);the Key R&D Plan of Shaanxi Province,China(No.2022SF-603).
SPP1^(+) macrophages have been identified as key players in the colorectal cancer(CRC) tumor microenvironment, but their function remains unclear. This study integrated single-cell and spatial transcriptomics with bul...
关键词:Colorectal cancer Immunotherapy Single-cell RNA sequencing Spatial transcriptomics SPP1þmacrophages 
Increased colorectal cancer risk in prediabetes:A meta-analysis
《World Journal of Diabetes》2025年第5期409-422,共14页Na Wang Tian-Yi Zhao Xiao Ma 
Supported by National High Level Hospital Clinical Research Funding,No.2023-NHLHCRF-YXHZ-ZRMS-06.
BACKGROUND Previous research yielded conflicting results regarding the association between prediabetes and colorectal cancer(CRC).AIM To systematically assess the incidence of CRC in individuals with prediabetes compa...
关键词:Colorectal cancer PREDIABETES INCIDENCE Risk factor META-ANALYSIS 
Research Progress of MAPK Signaling Pathway in Colorectal Cancer
《Journal of Clinical and Nursing Research》2025年第4期319-324,共6页Panpan Mao Weiyun Wu 
Colorectal cancer(CRC)is one of the most common malignancies.In recent years,despite the widespread application of new endoscopic techniques and continuous advancements in treatment methods that have improved the earl...
关键词:MAPK signaling pathway Colorectal cancer Regulation mechanism 
F-box protein 22: A prognostic biomarker for colon cancer associated with immune infiltration and chemotherapy resistance
《World Journal of Gastrointestinal Oncology》2025年第4期365-383,共19页Xiao-Fei Lu Hong-Wei Zhang Xiao Chang Yong-Ze Guo 
The study was reviewed and approved by institutional ethics board of Affiliated Hospital of Hebei Engineering University(No.:2024[K]005-01).
BACKGROUND Colon cancer represents a significant malignant neoplasm within the digestive system,characterized by a high incidence rate and substantial disease burden.The F-box protein 22(FBXO22)plays a role in forming...
关键词:Colorectal cancer F-box protein 22 BIOMARKER PROGNOSIS Tumor immunology 
Trends in nanomedicine for colorectal cancer treatment: Bibliometric and visualization analysis (2010-2024)
《World Journal of Gastrointestinal Oncology》2025年第4期451-465,共15页Yu-Ren Zhang Hui-Rong Zhu Hao-Ran Li Yue-Lei Cheng Sun-Hu Yang Su-Ling Sun Zheng Wang 
Supported by Shanghai Municipal Health Commission Research Project,No.202340156.
BACKGROUND Recently,numerous studies have reported the application of nanomedicines in colorectal cancer treatment.However,no systematic bibliometric analysis has been conducted to examine the potential and mechanisms...
关键词:BIBLIOMETRIC Citespace VOSviewer HOTSPOT NANOMEDICINE Colorectal cancer 
Spectral computed tomography parameters of primary tumors and lymph nodes for predicting tumor deposits in colorectal cancer
《World Journal of Radiology》2025年第4期12-21,共10页Yi-Fan Lai Zhao-Ming Liang Jing-Fang Li Jia-Ying Zhang Ding-Hua Xu Hai-Yang Dai 
BACKGROUND Tumor deposits(TDs)are an independent predictor of poor prognosis in colorec-tal cancer(CRC)patients.Enhanced follow-up and treatment monitoring for TD+patients may improve survival rates and quality of lif...
关键词:Spectral computed tomography Colorectal cancer Tumor deposits Predicting effectiveness 
Personalized treatment selection in colorectal cancer with peritoneal metastasis: Do we need statistically validated indicators or cultural shift?
《World Journal of Gastrointestinal Oncology》2025年第4期553-556,共4页Fabrizio D'Acapito Massimo Framarini Daniela Di Pietrantonio Giorgio Ercolani 
The study by Wu et al analyzed the correlation between nutritional and inflam-matory markers and prognosis in patients with colorectal cancer peritoneal metastasis.The authors propose the neutrophil-to-lymphocyte rati...
关键词:Colorectal cancer Peritoneal metastasis INFLAMMATION NUTRITION Biomarkers Prognosis Overall survival Cytoreductive surgery 
Prediction of perioperative complications in colorectal cancer via artificial intelligence analysis of heart rate variability
《World Journal of Gastrointestinal Surgery》2025年第4期290-299,共10页Miao-Miao Ge Li-Wen Wang Jun Wang Jiang Liu Peng Chen Xin-Xin Liu Gang Wang Guan-Wen Gong Zhi-Wei Jiang 
Supported by The Natural Science Foundation of Nanjing University of Chinese Medicine,No.XZR2021019;The Outstanding Young Doctor Program of Jiangsu Province of Chinese Medicine,No.2023QB0140;Project of National Clinical Research Base of Traditional Chinese Medicine in Jiangsu Province,No.JD2022SZ18;The Natural Science Foundation of Nanjing University of Chinese Medicine,No.KYCX21_1710.
BACKGROUND Heart rate variability(HRV)represents efferent vagus nerve activity,which is suggested to be related to fundamental mechanisms of tumorigenesis and to be a predictor of prognosis in various cancers.Therefor...
关键词:Colorectal cancer Heart rate variability COMPLICATIONS Perioperative period PREDICTION 
Pan-immune-inflammation in colon cancer:A prognostic biomarker and the role of tumor location in personalized care
《World Journal of Gastrointestinal Surgery》2025年第4期1-6,共6页Gaya Spolverato Giulia Capelli Floriane Noel Michele Steindler Andrew Alexander Gumbs 
Despite advances in surgery,chemotherapy,and radiotherapy,the treatment of colorectal cancer(CRC)requires more personalized approaches based on tumor biology and molecular profiling.While some relevant mutations have ...
关键词:Colorectal cancer Inflammatory biomarkers Tumor location Targeted therapy 
Brief insight regarding the use of transanal,laparoscopic,and robotic total mesorectal excision for rectal cancer
《World Journal of Gastrointestinal Surgery》2025年第4期7-11,共5页Kevan English 
In this article,we provide an important commentary on the original study Lu et al,which offers insight into the surgical efficacy of transanal total mesorectal excision(TaTME)vs laparoscopic total mesorectal excision(...
关键词:Colorectal cancer Total mesorectal excision Laparoscopic excision Surgical techniques Surgical outcomes 
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