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CULTURED: 作品数：607被引量：1901H指数：17; 导出分析报告; 相关领域：医药卫生更多>>; 相关作者：王若峥胡云辉郑建全王明山潘景业更多>>; 相关机构：中国科学院上海生命科学研究院南京医科大学浙江大学医学院附属第二医院新疆医科大学附属肿瘤医院更多>>; 相关期刊：更多>>; 相关基金：国家自然科学基金国家重点基础研究发展计划国家高技术研究发展计划北京市自然科学基金更多>>

Differential development and electrophysiological activity in cultured cortical neurons from the mouse and cynomolgus monkey: 《Neural Regeneration Research》2021年第12期2446-2452,共7页Xue-Yan Zhang Jun Li Cai-Juan Li Ying-Qi Lin Chun-Hui Huang Xiao Zheng Xi-Chen Song Zhu-Chi Tu Xiao-Jiang Li Sen Yan; This work was supported by the National Natural Science Foundation of China,No.81922026(to SY);the National Key Research and Development Program of China Stem Cell and Translational Research,No.2017YFA0105104(to SY);Key Field Research and Development Program of Guangdong Province,No.2018B030337001(to XJL);Guangdong Key Laboratory of Non-human Primate Models of Brain Diseases,No.2020B121201006(to XJL);Guangzhou Key Research Program on Brain Science,No.202007030008(to SY);the Fundamental Research Funds for the Central Universities,No.21619104(to SY).; In vitro cultures of primary cortical neurons are widely used to investigate neuronal function.However,it has yet to be fully investigated whether there are significant differences in development and function between ...; 关键词：Axion-MEA electrical activities human disease model Huntington’s disease HTT monkey neuron morphometric analysis mouse neuron neurodegenerative diseases primary culture

Neuroprotective effects of ganoderma lucidum polysaccharides against oxidative stress-induced neuronal apoptosis被引量：15: 《Neural Regeneration Research》2017年第6期953-958,共6页Xin-zhi Sun Ying Liao Wei Li Li-mei Guo; Ganoderma lucidum polysaccharides have protective effects against apoptosis in neurons exposed to ischemia/reperfusion injury, but the mechanisms are unclear. The goal of this study was to investigate the underlying m...; 关键词：neuronal lucidum oxidative caspase suppressed protective peroxide inhibit regulate cultured

Identification of α7 nicotinic acetylcholine receptor on hippocampal astrocytes cultured in vitro and its role on inflammatory mediator secretion被引量：3: 《Neural Regeneration Research》2012年第22期1709-1714,共6页Yan Wang Ning Zhu Kewan Wang Zhongyi Zhang Yong Wang; supported by the National Natural Science Foundation of China,No.30471928 and No.30973162;the Natural Science Foundation of Guangdong Province,No.07005203; The present study found expressions of a7 nicotinic acetylcholine receptor on hippocampal slices and hippocampal astrocytes using double immunofluorescence stainings. Expression of glial fibdllary acidic protein in th...; 关键词：α7 nicotinic acetylcholine receptor ASTROCYTES inflammation CYTOKINES chemotactic factor amyloidβ protein HIPPOCAMPUS neural regeneration

Methyl 3,4-dihydroxybenzoate promotes neurite outgrowth of cortical neurons cultured in vitro被引量：2: 《Neural Regeneration Research》2012年第13期971-977,共7页Zheng Zhang Xing Zhou Xiaowen Zhou Xiao Xu Minjing Liao Li Yan Ruohua Lv Huanmin Luo; supported by the National Natural Science Foundation of China,No.30672450,81173037;the National Program on Key Basic Research Project (973 Program),No.2011CB707500; Cerebral cortical neurons from neonatal rats were cultured in the presence of methyl 3,4-dihydroxybenzoate （MDHB; 2, 4, and 8 IJM）. Results showed that MDHB significantly promoted neurite outgrowth and microtubule-a...; 关键词：methyl 3 4-dihydroxybenzoate neurite outgrowth brain-derived neurotrophic factor neurodegenerative diseases neural regeneration

T-type calcium channel expression in cultured human neuroblastoma cells: 《Neural Regeneration Research》2011年第31期2410-2413,共4页Xianjie Wen Shiyuan Xu Lingling Wang Hua Liang Chengxiang Yang Hanbing Wang Hongzhen Liu; the National Natural Science Foundation of China,No.81100831;the Medical Science Foundation of Guangdong Health Department,No.B2011303; Human neuroblastoma cells （SH-SY5Y） have similar structures and functions as neural cells and have been frequently used for cell culture studies of neural cell functions.Previous studies have revealed L-and N-type c...; 关键词：calcium ion channel calcium signaling cell culture neural regeneration real-time PCR T-type calcium channel western blot neural regeneration

Granulocyte colony-stimulating factor promotes growth of processes,growth associated protein 43 and microtubule-associated protein 2 expression in cultured rat retinal ganglion cells in vitro: 《Neural Regeneration Research》2011年第31期2435-2440,共6页Haitao Xu Yuying Jiang Xiuhong Qin Lihui Si Jie Zhao Lijuan Liu Yazhen Wu; Following granulocyte colony-stimulating factor （G-CSF） treatment,the growth of processes in cul-tured rat retinal ganglion cells （RGCs） in vitro,expression of growth associated protein 43,and expression of microt...; 关键词：granulocyte colony-stimulating factor ganglion cells growth-associated protein 43 microtubule-associated protein 2 AXONS neural regeneration

Nitric oxide promotes survival of cerebellar granule neurons cultured in vitro through the Akt pathway: 《Neural Regeneration Research》2011年第20期1559-1563,共5页Lin Wang Mei Li Lihua Zhou; the National Natural Science Foundation of China, No. 81070995;Guangdong Provincial Science Foundation, No.05001726, 1050175; In this study, cerebellar granule neurons were used to examine the role of nitric oxide on cell survival. The N-methyI-D-aspartic acid receptor antagonist, MK-801, and the soluble guanylate cyclase antagonist, 1H-[1, ...; 关键词：nitric oxide cerebellar granule neurons development apoptosis AKT cyclic guanosine monophosphate neural regeneration

Protective effects of berberine against amyloid beta-induced toxicity in cultured rat cortical neurons被引量：1: 《Neural Regeneration Research》2011年第3期183-187,共5页Wang, Jing Zhang, Yanjun Du, Shuai Zhang, Mixia; the Key Project of Ministry of Education of China,No. 208009;the National Science & Technology Major Project "Key New Drug Creation and Manufacturing Program",China,No. 2009ZX09308-005; Berberine, a major constituent of Coptidis rhizoma, exhibits neural protective effects. The present study analyzed the potential protective effect of berberine against amyloid β-induced cytotoxicity in rat cerebral c...; 关键词：activated caspase-3 amyloid β BERBERINE cortical neurons

Effects of brain-derived neurotrophic factor on synapsin expression in rat spinal cord anterior horn neurons cultured in vitro被引量：1: 《Neural Regeneration Research》2010年第16期1243-1248,共6页Zhifei Wang Daguang Liao Changqi Li; Brain-derived neurotrophic factor （BDNF） promotes synaptic formation and functional maturation by upregulating synapsin expression in cortical and hippocampal neurons. However, it remains controversial whether BDNF ...; 关键词：brain-derived neurotrophic factor synapsin I SYNAPTOPHYSIN cell culture spinal cord neurons rats neural regeneration

Effect of ciliary neurotrophic factor on bcl-2 and c-jun gene and protein expression in cultured retinal nerve cells: 《Neural Regeneration Research》2010年第9期662-667,共6页Xiang Zhang Xiang Lei Yueyue Liu Genlin Li; the National Natural Science Foundation of China,No. 30973262; BACKGROUND：In various retinal neurodegenerative animal models,ciliary neurotrophic factor （CNTF） exhibits prominent neuroprotective effects on retinal nerve cells.Bcl-2 is an anti-apoptotic protein.c-Jun is upregul...; 关键词：ciliary neurotrophic factor C-JUN BCL-2 APOPTOSIS nerve cells RETINA neural factor neural regeneration

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