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作品数:3388被引量:5816H指数:21
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相关机构:东南大学上海交通大学中国科学院复旦大学更多>>
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Detection,regulation,and functions of RNA N^(6)-methyladenosine modification in plants被引量:4
《Plant Communications》2023年第3期32-46,共15页Jun Tang Shuyan Chen Guifang Jia 
supported by the National Natural Science Foundation of China(22225704,21820102008,92053109);the National Basic Research Program of China(2019YFA0802201);the Beijing Natural Science Foundation(Z200010).
N6-Methyladenosine(m^(6)A)is the most abundant internal chemical modification in eukaryotic mRNA and plays important roles in gene expression regulation,including transcriptional and post-transcriptional regulation.m^...
关键词:RNA modification m^(6)A PLANTS epitranscriptome 
Exponential isothermal amplification coupled MALDI-TOF MS for microRNAs detection
《Chinese Chemical Letters》2023年第2期322-326,共5页Guobin Han Dandan Li Qiuyuan Lin Jia Yi Qian Lyu Qingwei Ma Liang Qiao 
supported by the National Natural Science Foundation of China (NSFC, Nos. 22022401, 22074022 and 21934001);the Ministry of Science and Technology of China (Nos. 2020YFF0426500, 2020YFF0304502)。
Micro RNAs(mi RNAs) have attracted significant attention in biomedical research and clinical diagnosis.However, due to their inherent characteristics of low abundance and the high complexity of corresponding biologica...
关键词:Micro RNA EXPAR Isothermal amplification MALDI-TOF MS Breast cancer cells 
Detection of electron-phonon coupling in two-dimensional materials by light scattering被引量:1
《Nano Research》2021年第6期1711-1733,共23页Jia-Min Lai Ya-Ru Xie Jun Zhang 
J.Z.acknowledges support from Beijing Natural Science Foundation(No.JQ18014);the National Basic Research Program of China(Nos.2016YFA0301200 and 2017YFA0303401);Strategic Priority Research Program of Chinese Academy of Sciences(No.XDB28000000);the National Natural Science Foundation of China(No.51527901).
Electron-phonon coupling affects the properties of two-dimensional(2D)materials significantly,leading to a series of novel phenomena.Inelastic light scattering provides a powerful experimental tool to explore electron...
关键词:electron-phonon coupling Raman scattering Brillouin scattering two-dimensional(2D)materials 
Ultrasensitive assays for detection of plasma tau and phosphorylated tau 181 in Alzheimer's disease:a systematic review and meta-analysis被引量:4
《Translational Neurodegeneration》2021年第1期112-125,共14页Xulong Ding Shuting Zhang Lijun Jiang Lu Wang Tao Li Peng Lei 
supported by the Ministry of Science and Technology of China(2018YFC1312300);the National Natural Science Foundation of China(81722016)。
A lack of convenient and reliable biomarkers for diagnosis and prognosis is a common challenge for neurodegenerative diseases such as Alzheimer's disease(AD).Recent advancement in ultrasensitive protein assays has all...
关键词:TAU Phosphorylated tau 181 Alzheimer's disease Simoa IMR EIMAF/a-EIMAF MSD Plasma biomarker 
Deep learning in digital pathology image analysis:a survey被引量:4
《Frontiers of Medicine》2020年第4期470-487,共18页Shujian Deng Xin Zhang Wen Yan Eric I-Chao Chang Yubo Fan Maode Lai Yan Xu 
This work was supported by the National Science and Technology Major Project of the Ministry of Science and Technology of China(No.2017YFC0110903);Microsoft Research under the eHealth program;the National Natural Science Foundation of China(No.81771910);the Beijing Natural Science Foundation in China(No.4152033);the Technology and Innovation Commission of Shenzhen in China(No.shenfagai2016-627);the Beijing Young Talent Project in China,the Fundamental Research Funds for the Central Universities of China(No.SKLSDE-2017ZX-08)from the State Key Laboratory of Software Development Environment in Beihang University in China,and the 111 Project in China(No.B13003).
deep learning(DL)has achieved state-of-the-art performance in many digital pathology analysis tasks.Traditional methods usually require hand-crafted domain-specific features,and DL methods can learn representations wi...
关键词:PATHOLOGY deep learning SEGMENTATION DETECTION CLASSIFICATION 
Redesigned Duplex RT-qPCR for the Detection of GI and GII Human Noroviruses被引量:2
《Engineering》2020年第4期442-448,共7页Danlei Liu Zilei Zhang Qingping Wu Peng Tian Haoran Geng Ting Xu Dapeng Wang 
supported by the Ministry of Science and Technology of China(2017YFC1601200);the National Natural Science Foundation of China(31772078);the Agri-X Interdisciplinary Fund of Shanghai Jiao Tong University(2017).
Human noroviruses(HuNoVs)are major foodborne pathogens that cause nonbacterial acute gastroenteritis worldwide.As the tissue-culture system for HuNoVs is not mature enough for routine detection of the virus,detection ...
关键词:Human noroviruses RT-QPCR REDESIGN Primer Probe DETECTION 
CGNet:cross-guidance network for semantic segmentation被引量:11
《Science China(Information Sciences)》2020年第2期49-64,共16页Zhijie ZHANG Yanwei PANG 
supported in part by the Science and Technology Innovation 2030-Major Project of Artificial Intelligence of the Ministry of Science and Technology of China(Grant No.2018AAA01028);part by National Natural Science Foundation of China(Grant No.61632018).
Semantic segmentation is a fundamental task in image analysis.The issue of semantic segmentation is to extract discriminative features for distinguishing different objects and recognizing hard examples.However,most ex...
关键词:SEMANTIC SEGMENTATION fully convolutional networks pyramid NETWORK edge DETECTION saliency DETECTION cross-guidance 
Principal-component estimates of the Kuroshio Current axis and path based on the mathematical verification between satellite altimeter and drifting buoy data被引量:2
《Acta Oceanologica Sinica》2020年第1期14-24,共11页Zhanpeng Zhuang Zhenli Hui Guangbing Yang Xinhua Zhao Yeli Yuan 
The National Science and Technology Major Project of the Ministry of Science and Technology of China under contract No.2018YFF01014100;the National Programme on Global Change and Air-Sea Interaction under contract No.GASI-IPOVAI-01-05;the NSFC-Shandong Joint Fund for Marine Science Research Centers under contract No.U1606405
We used satellite altimetry data to investigate the Kuroshio Current because of the higher resolution and wider range of observations. In previous studies, satellite absolute geostrophic velocities were used to study ...
关键词:Kuroshio axis detection Kuroshio path detection mathematical verification satellite absolute geostrophic velocity principal-component detection 
One-dimensional and two-dimensional nanomaterials for the detection of multiple biomolecules
《Chinese Chemical Letters》2019年第9期1557-1564,共8页Quan Wang Xudong Wang Min Xu Xiaoding Lou Fan Xia 
supported by the National Natural Science Foundation of China (Nos. 21525523, 21722507, 21574048, 21874121);the National Basic Research Program of China (973 Program, No. 2015CB932600);the National Key R&D Program of China (Nos. 2017YFA020800, 2016YFF0100800);Natural Science Foundation of Zhejiang Province of China (No. LY18B050002)
The complexity of biological samples determines that the detection of a single biomolecule is unable to satisfy actual needs. Moreover, the "false positives" results caused by a single biomolecule detections easily le...
关键词:ONE-DIMENSIONAL NANOMATERIALS TWO-DIMENSIONAL NANOMATERIALS DETECTION MULTIPLE TARGETS Biomolecules 
Automatic Detection of Lung Nodules Using 3D Deep Convolutional Neural Networks被引量:2
《Journal of Shanghai Jiaotong university(Science)》2019年第4期517-523,共7页FU Ling MA Jingchen CHEN Yizhi LARSSON Rasmus ZHAO Jun 
the National Natural Science Foundation of China(No.81371624);the National Key Research and Development Program of China(No.2016YFC0104608);the National Basic Research Program of China(No.2010CB834302);the Shanghai Jiao Tong University Medical Engineering Cross Research Funds(Nos.YG2013MS30 and YG2014ZD05)
Lung cancer is the leading cause of cancer deaths worldwide. Accurate early diagnosis is critical in increasing the 5-year survival rate of lung cancer, so the efficient and accurate detection of lung nodules,the pote...
关键词:LUNG NODULE DETECTION COMPUTER-AIDED DETECTION (CAD) convolutional NEURAL NETWORK (CNN) fully convolutional NEURAL NETWORK (FCN) 
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