supported by the National Natural Science Foundation of China(22225704,21820102008,92053109);the National Basic Research Program of China(2019YFA0802201);the Beijing Natural Science Foundation(Z200010).
N6-Methyladenosine(m^(6)A)is the most abundant internal chemical modification in eukaryotic mRNA and plays important roles in gene expression regulation,including transcriptional and post-transcriptional regulation.m^...
supported by the National Natural Science Foundation of China (NSFC, Nos. 22022401, 22074022 and 21934001);the Ministry of Science and Technology of China (Nos. 2020YFF0426500, 2020YFF0304502)。
Micro RNAs(mi RNAs) have attracted significant attention in biomedical research and clinical diagnosis.However, due to their inherent characteristics of low abundance and the high complexity of corresponding biologica...
J.Z.acknowledges support from Beijing Natural Science Foundation(No.JQ18014);the National Basic Research Program of China(Nos.2016YFA0301200 and 2017YFA0303401);Strategic Priority Research Program of Chinese Academy of Sciences(No.XDB28000000);the National Natural Science Foundation of China(No.51527901).
Electron-phonon coupling affects the properties of two-dimensional(2D)materials significantly,leading to a series of novel phenomena.Inelastic light scattering provides a powerful experimental tool to explore electron...
supported by the Ministry of Science and Technology of China(2018YFC1312300);the National Natural Science Foundation of China(81722016)。
A lack of convenient and reliable biomarkers for diagnosis and prognosis is a common challenge for neurodegenerative diseases such as Alzheimer's disease(AD).Recent advancement in ultrasensitive protein assays has all...
This work was supported by the National Science and Technology Major Project of the Ministry of Science and Technology of China(No.2017YFC0110903);Microsoft Research under the eHealth program;the National Natural Science Foundation of China(No.81771910);the Beijing Natural Science Foundation in China(No.4152033);the Technology and Innovation Commission of Shenzhen in China(No.shenfagai2016-627);the Beijing Young Talent Project in China,the Fundamental Research Funds for the Central Universities of China(No.SKLSDE-2017ZX-08)from the State Key Laboratory of Software Development Environment in Beihang University in China,and the 111 Project in China(No.B13003).
deep learning(DL)has achieved state-of-the-art performance in many digital pathology analysis tasks.Traditional methods usually require hand-crafted domain-specific features,and DL methods can learn representations wi...
supported by the Ministry of Science and Technology of China(2017YFC1601200);the National Natural Science Foundation of China(31772078);the Agri-X Interdisciplinary Fund of Shanghai Jiao Tong University(2017).
Human noroviruses(HuNoVs)are major foodborne pathogens that cause nonbacterial acute gastroenteritis worldwide.As the tissue-culture system for HuNoVs is not mature enough for routine detection of the virus,detection ...
supported in part by the Science and Technology Innovation 2030-Major Project of Artificial Intelligence of the Ministry of Science and Technology of China(Grant No.2018AAA01028);part by National Natural Science Foundation of China(Grant No.61632018).
Semantic segmentation is a fundamental task in image analysis.The issue of semantic segmentation is to extract discriminative features for distinguishing different objects and recognizing hard examples.However,most ex...
The National Science and Technology Major Project of the Ministry of Science and Technology of China under contract No.2018YFF01014100;the National Programme on Global Change and Air-Sea Interaction under contract No.GASI-IPOVAI-01-05;the NSFC-Shandong Joint Fund for Marine Science Research Centers under contract No.U1606405
We used satellite altimetry data to investigate the Kuroshio Current because of the higher resolution and wider range of observations. In previous studies, satellite absolute geostrophic velocities were used to study ...
supported by the National Natural Science Foundation of China (Nos. 21525523, 21722507, 21574048, 21874121);the National Basic Research Program of China (973 Program, No. 2015CB932600);the National Key R&D Program of China (Nos. 2017YFA020800, 2016YFF0100800);Natural Science Foundation of Zhejiang Province of China (No. LY18B050002)
The complexity of biological samples determines that the detection of a single biomolecule is unable to satisfy actual needs. Moreover, the "false positives" results caused by a single biomolecule detections easily le...
the National Natural Science Foundation of China(No.81371624);the National Key Research and Development Program of China(No.2016YFC0104608);the National Basic Research Program of China(No.2010CB834302);the Shanghai Jiao Tong University Medical Engineering Cross Research Funds(Nos.YG2013MS30 and YG2014ZD05)
Lung cancer is the leading cause of cancer deaths worldwide. Accurate early diagnosis is critical in increasing the 5-year survival rate of lung cancer, so the efficient and accurate detection of lung nodules,the pote...