DICER

作品数：163被引量：380H指数：8
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An NF90/NF110-mediated feedback amplification loop regulates dicer expression and controls ovarian carcinoma progression被引量：3
《Cell Research》2018年第5期556-571,共16页Jerome Barbier Xin Chen Gabriel Sanchez Muyan Cai Marion Helsmoortel Takuma Higuchi Pierre Giraud Xavier Contreras Gangjun Yuan Zihao Feng Rima Nait-Saidi Olivier Deas Lisa Bluy Jean-Gabriel Judde Sylvie Rouquier William Ritchie Shuji Sakamoto Dan Xie Rosemary Kiernan 
Reduced expression of DICER, a key enzyme in the miRNA pathway, is frequently associated with aggressive, invasive disease, and poor survival in various malignancies. Regulation of DICER expression is, however, poorly...
关键词：控制处理 DICER 卵巢 癌症 反馈 DICER miRNA 调整 
Dicer-independent RNA-directed DNA methylation in Arabidopsis被引量：2
《Cell Research》2016年第11期1264-1264,共1页Dong-Lei Yang Guiping Zhang Kai Tang Jingwen Li Lan Yang Huan Huang Heng Zhang Jian-Kang Zhu 
Drosha and Dicer： Slicers cut from the same cloth
《Cell Research》2016年第5期511-512,共2页Sisi Li Dinshaw J Patel 
DROSHA and its partner DGCR8 form a heterotrimeric complex named Microprocessor, which is essential for microRNA biogenesis. A recent study by Kwon et al. in Cell reveals the structure of a DROSHA construct in complex...
关键词：DICER 切片机 微处理器 RNA合成 异三聚体 合作伙伴 末端区域 裂解活性 
Dicer-independent RNA-directed DNA methylation in Arabidopsis被引量：5
《Cell Research》2016年第1期66-82,共17页Dong Lei Yang Guiping KaiFang Jingwen Lan Yang HuanHuang HengZhung Jian Kang zhu 
RNA-Dirccicd DNA mcthylation（RdDM）is an imporiant de novo DNA mcthylution pathway in plant.Small interfering RNAs…are requircd to maintain DNAmethylation at only a subect of loct.
关键词：siRNA non-coding RNA polly Dicor like PdDM.DNA meihylation 
A novel mechanism underlies caspase-dependent conversion of the dicer ribonuclease into a deoxyribonuclease during apoptosis
《Cell Research》2014年第2期218-232,共15页Xiao Ge Xiang Zhao Akihisa Nakagawa Xinqi Gong Riley Robert Skeen-Gaar Yong Shi Haipeng Gong Xinquan Wang Ding Xue 
During C. elegans apoptosis, the dicer ribonuclease （DCR-1） is cleaved by the cell death protease CED-3 to generate a truncated DCR-1 （tDCR-1） with one and a half ribonuclease III （RNase III） domains, converting...
关键词：C. elegans dicer ribonuclease DEOXYRIBONUCLEASE CASPASE APOPTOSIS CONVERSION 
A role for the RNA-binding protein MOS2 in microRNA maturation in Arabidopsis被引量：7
《Cell Research》2013年第5期645-657,共13页Xueying Wu Yupeng Shi Jingrui Li Le Xu Yuda Fang Xin Li Yijun Qi 
microRNAs （miRNAs） play important roles in the regulation of gene expression. In Arabidopsis, mature miRNAs are processed from primary miRNA transcripts （pri-miRNAs） by nuclear HYL1/SE/DCL1 complexes that form Dic...
关键词：MIRNA RNA binding protein ARABIDOPSIS DICER 
A new twist in the microRNA pathway： Not Dicer but Argonaute is required for a microRNA production被引量：6
《Cell Research》2010年第7期735-737,共3页Gabriel D Bosse Martin J Simard 
Found in all metazoans, microRNAs or miRNAs are small non-coding RNA of-22 nucleotides in length that completely reshaped our understanding of gene regulation. This new class ofgene regulator is mostly transcribed by ...
关键词：小RNA DICER 微RNA miRNA 英雄 生产 非编码RNA 小分子RNA 
Epigenetics： heterochromatin meets RNAi被引量：7
《Cell Research》2009年第3期282-295,共14页Ingela Djupedal Karl Ekwall 
The term epigenetics refers to heritable changes not encoded by DNA. The organization of DNA into chromatin fibers affects gene expression in a heritable manner and is therefore one mechanism of epigenetic inheritance...
关键词：EPIGENETICS HETEROCHROMATIN RNAI siRNA ARGONAUTE DICER RNA dependent polymerase 
Biochemical mechanisms of the RNA-induced silencing complex被引量：5
《Cell Research》2007年第3期187-194,共8页Zain Paroo Qinghua Liu Xiaodong Wang 
In less than 10 years since its inception, RNA interference （RNAi） has had extraordinary impact on biomedical science. RNAi has been demonstrated to influence numerous biological and disease pathways. Development an...
关键词：ARGONAUTE DICER dsRBP RISC RNA interference 
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