HETEROCHROMATIN

作品数:32被引量:105H指数:6
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相关作者:黄海焦仁杰更多>>
相关机构:北京大学香港中文大学中山大学中国科学院更多>>
相关期刊:《American Journal of Molecular Biology》《Journal of Zhejiang University-Science B(Biomedicine & Biotechnology)》《Molecular Plant》《Radiation Medicine and Protection》更多>>
相关基金:国家自然科学基金国家重点基础研究发展计划广东省自然科学基金王宽诚敎育基金更多>>
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Correction to:SIRT7 antagonizes human stem cell aging as a heterochromatin stabilizer
《Protein & Cell》2024年第1期76-77,共2页
This is a correction to:Shijia Bi and others,SIRT7 antagonizes human stem cell aging as a heterochromatin stabilizer,Protein&Cell,Volume 11,Issue 7,July 2020,Pages 483-504,https://doi.org/10.1007/s13238-020-00728-4 Th...
关键词:CORRECTION AGING STABILIZER 
Effects of SWI/SNF complex on DNA damage repair in heterochromatin of embryonic fibroblast cells
《Radiation Medicine and Protection》2023年第4期214-220,共7页Hong Zhang Yinyin Shu Mintao Ji 
supported by grants from National Natural Science Foundation of China(31971165 and 82173465);Leading Talents Program of Gusu District(ZXL2022454);Jiangsu Provincial Outstanding Postdoctoral Program(2023ZB254),China.
Objective:To investigate the impact of SWI/SNF complex on heterochromatin DNA damage repair after exposure to X-ray irradiation,in order to explore the underlying mechanism.Methods:NIH3T3 and MRC5 cells were treated w...
关键词:SWI/SNF complex BRM/BRG1 HETEROCHROMATIN DNA damage repair YAP/TAZ 
Genome-wide distribution and functions of the AAE complex in epigenetic regulation in Arabidopsis
《Journal of Integrative Plant Biology》2021年第4期707-722,共16页Yi-Zhe Zhang Juncheng Lin Zhizhong Ren Chun-Xiang Chen Daisuke Miki Si-Si Xie Jian Zhang Ya-Nan Chang Jing Jiang Jun Yan Qingshun Q.Li Jian-Kang Zhu Cheng-Guo Duan 
supported by the Chinese Academy of Sciences,including the Strategic Priority Research Program of the Chinese Academy of Sciences(XDB27040203 to C.-G.D.and XDB27040000 to J.K.Z);in part by a grant from the National Key Research and Development Project of China(2016YFE0108800 to Q.Q.L.)。
Heterochromatin is widespread in eukaryotic genomes and has diverse impacts depending on its genomic context.Previous studies have shown that a protein complex,the ASI1-AIPP1-EDM2(AAE)complex,participates in polyadeny...
关键词:alternative polyadenylation alternative splicing epigenetic regulation HETEROCHROMATIN TRANSCRIPTION 
Interplay between genome organization and epigenomic alterations of pericentromeric DNA in cancer
《Journal of Genetics and Genomics》2021年第3期184-197,共14页Subhadip Kundu M.D.Ray Ashok Sharma 
the Department of Science and Technology(DST-SERB),India,for funding(DST grant number:ECR/2016/001740);University Grants Commission,India,for fellowship support。
In eukaryotic genome biology,the genomic organization inside the three-dimensional(3D)nucleus is highly complex,and whether this organization governs gene expression is poorly understood.Nuclear lamina(NL)is a filamen...
关键词:LADs Pericentromere Heterochromatin Gene regulation Epigenetics Cancer Genome organization 
Stabilization of heterochromatin by CLOCK promotes stem cell rejuvenation and cartilage regeneration被引量:15
《Cell Research》2021年第2期187-205,共19页Chuqian Liang Zunpeng Liu Moshi Song Wei Li Zeming Wu Zehua Wang Qiaoran Wang Si Wang Kaowen Yan Liang Sun Tomoaki Hishida Yanning Cai Juan Carlos lzpisua Belmonte Pedro Guillen Piu Chan Qi Zhou Weiqi Zhang Jing Qu Guang-Hui Liu 
This work was supported by the Strategic Priority Research Program of the Chinese Academy of Sciences(XDA16010100);the National Key R&D Program of China(2018YFC2000100,2018YFA0107203,2017VFA0102802,2017YFA0103304,2015CB964800,2019YFA0110100);the National Natural Science Foundation of China(81861168034,81921006,81625009,91749202,31671429,91949209,81671377,91749123,81822018,81870228,31801010,81922027,81701388);Program of Beijing Municipal Science and Technology Commission(Z191100001519005);Beijing Natural Science Foundation(Z190019);Beijing Municipal Commission of Health and Family Planning(PXM2018_026283_000002);Advanced Innovation Center for Human Brain Protection(3500-1192012);the Key Research Program of the Chinese Academy of Sciences(KFZD-SW-221);K.C.Wong Education Foundation(GJTD-2019-06,GJTD-2019-08);Youth Innovation Promotion Association of CAS(2016093);the State Key Laboratory of Stem Cell and Reproductive Biology;the State Key Laboratory of Membrane Biology;P.G.was supported by MAPHRE and Fundacion Pedro Guillen.
Accumulating evidence indicates an association between the circadian clock and the aging process.However,it remains elusive whether the deregulation of circadian clock proteins underlies stem cell aging and whether th...
关键词:DEGENERATION stabilizing CLOCK 
SIRT7 slows down stem cell aging by preserving heterochromatin:a perspective on the new discovery被引量:1
《Protein & Cell》2020年第7期469-471,共3页Luyang Sun Weiwei Dang 
Stem cell aging is one of the leading theories of aging and is gaining momentum in recent years with the development of new technologies to study stem cells(Schultz&Sinclair,2016).In the stem cell aging theory,the age...
关键词:AGING process. Sinclair 
SIRT7 antagonizes human stem cell aging as a heterochromatin stabilizer被引量:22
《Protein & Cell》2020年第7期483-504,共22页Shijia Bi Zunpeng Liu Zeming Wu Zehua Wang Xiaoqian Liu Si Wang Jie Ren Yan Yao Weiqi Zhang Moshi Song Guang-Hui Liu Jing Qu 
SIRT7,a sirtuin family member implicated in aging and disease,is a regulator of metabolism and stress responses.It remains elusive how human somatic stem cell populations might be impacted by SIRT7.Here,we found that ...
关键词:SIRT7 stem cell AGING LINE1 cGAS STING 
Arabidopsis PEAPODs function with LIKE HETEROCHROMATIN PROTEIN1 to regulate lateral organ growth被引量:1
《Journal of Integrative Plant Biology》2020年第6期812-831,共20页Ying Zhu Xiao Luo Xuxin Liu Wenjuan Wu Xiaofeng Cui Yuehui He Jirong Huang 
supported by grants from National Science Foundation of China(31771547);Chinese National Special Grant for Transgenic Crops(2016ZX08009003-005)。
In higher plants,lateral organs are usually of determinate growth.It remains largely elusive how the determinate growth is achieved and maintained.Previous reports have shown that Arabidopsis PEAPOD(PPD)proteins suppr...
关键词:ARABIDOPSIS FUNCTION ORGANS 
The Long-Sought-After Plant Heterochromatin Protein 1
《Molecular Plant》2019年第1期14-15,共2页Rong Chen 
Heterochromatin,being transcriptionally inactive,is the highly condensed form of chromatin that is associated with Histone H3 lysine 9 methylation (H3K9me)and DNA methylation in eukaryotic cells.In fission yeast and a...
关键词:HETEROCHROMATIN H3K9me ANIMALS 
Plant HP1 protein ADCP1 links multivalent H3K9 methylation readout to heterochromatin formation被引量:11
《Cell Research》2019年第1期54-66,共13页Shuai Zhao Lingling Cheng Yifei Gao Baichao Zhang Xiangdong Zheng Liang Wang Pilong Li Qianwen Sun Haitao Li 
the National Key R&D Program (2016YFAOSO0700 to H.L.,and 2016YFA0500800 to Q.S.);the National Science Foundation of China (31725014,91753203 to H.L.,and 31571322 to Q.S.);the Tsinghua University Initiative Scientific Research Program (to H.L.and Q.S.).Q.S.and P.L.are supported by the 1000 Young Talent Program of China.
Heterochromatin Protein 1 (HP1) recognizes histone H3 lysine 9 methylation (H3K9me) through its conserved chromodomain and maintains heterochromatin from fission yeast to mammals. However, in Arabidopsis, Like Heteroc...
关键词:HETEROCHROMATIN PROTEIN 1 (HP1) Like HETEROCHROMATIN PROTEIN 1 (LHP1) 
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