Ribonucleotide reductase(RNR)catalyses the only known de novo pathway for the production of all four deoxyribonucleotides that are required for DNA synthesis1,2.It is essential for all organisms that use DNA as their ...
This work was supported by the National Natural Science Foundation of China(81573405 and U1502225);Natural Science Foundation of Beijing(7212159);National Key R&D Program of China(2016YFC0800907);National Key R&D Program of China(2017YFC131040);Medical Innovation Program(16CXZ033);Beijing Nova Program(xx2014A014).
Drug addiction is characterized by relapse when addicts are re-exposed to drug-associated environmental cues,but the neural mechanisms underlying cue-induced relapse are unclear.In the present study we investigated th...
supported by the Natural Science Foundation of Shandong Province,China(No.ZR2019QB010);National Natural Science Foundation of China(Nos.21705095,21775088);the Scientific Research Foundation of Qufu Normal University(No.BS D20130117).
Dopamine(DA)is easy to be oxidized and polymerizes to form polydopamine(pDA)in alkaline conditions,while the synthesis is usually time-consuming(48 h).Herein,the polymerization of DA is completed with 4 h under the ca...
the National Natural Science Foundation of China(22075050,21634003);the Ministry of Science and Technology of China(2016YFA0203302);the Science and Technology Commission of Shanghai Municipality(20JC1414902);Shanghai Municipal Education Commission(2017-01-07-00-07-E00062)。
Achieving real-time,continuous and long-term monitoring of dopamine(DA)in vivo is essential for revealing brain functions and preventing and treating neurogenic diseases.However,it remains challenging to achieve a low...
National Natural Science Foundation of China(61805126);Tsinghua University Initiative Scientific Research Program(20193080076).
Dopamine(DA),as a neurotransmitter in human brain,plays a crucial role in reward motivation and motor control.An improper level of DA can be associated with neurological disorders such as schizophrenia and Parkinson’...
This study was financially supported by TCM Administration Project of Guangdong Province,China(No.20203010);Science and Technology Program of Guangdong,China(No.2020A151501325).
Traditional Chinese medicine Buyi Ganshen therapy combined with dopa preparation in the therapy of Parkinson’s disease could enhance the clinical safety and efficacy compared with dopa preparation along.The exact mec...