DOPA

作品数:66被引量:114H指数:5
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相关领域:医药卫生更多>>
相关作者:陈双扣胡道道廖智杨丽君梁华民更多>>
相关机构:吉林大学天津工业大学重庆医科大学华东理工大学更多>>
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^(18)F-DOPA和^(18)F-FP-CIT显影剂在PET/CT诊断早期帕金森病及评估疾病严重程度中的应用价值
《中国临床新医学》2024年第7期772-777,共6页唐亚洲 邓玉娇 熊婵玉 罗永杰 
四川省科技厅重点研发项目(编号:2019YFS0214)。
目的探讨^(18)F-DOPA和^(18)F-FP-CIT显影剂在正电子发射计算机断层/电子计算机断层扫描(PET/CT)诊断早期帕金森病(PD)及评估疾病严重程度中的应用价值。方法回顾性分析2022年1月至2023年3月四川省医学科学院·四川省人民医院神经内科...
关键词:帕金森病 多巴胺转运体显像 多巴胺显像 正电子发射计算机断层/电子计算机断层扫描 
重组贻贝粘蛋白Mfp-3P的制备及促进伤口愈合的作用被引量:2
《生物工程学报》2024年第5期1498-1508,共11页郝东 魏文培 周浩 李敏 乔莎 赵硕文 侯增淼 
为了研究重组贻贝粘蛋白的制备方法及其在伤口愈合中的作用,本研究将贻贝的Mfp-3和preCol-P肽部分片段进行融合,以毕赤酵母为宿主微生物进行表达,经过发酵和纯化,获得了纯的重组贻贝粘蛋白产物,并在细胞水平检测其对小鼠成纤维细胞L929...
关键词:贻贝粘蛋白 基因重组 生物材料 内毒素 3 4-二羟基苯丙氨酸(DOPA) 
Metal-free ribonucleotide reduction powered by a DOPA radical in Mycoplasma pathogens
《四川生理科学杂志》2023年第10期1817-1817,共1页Vivek Srinivas 
Ribonucleotide reductase(RNR)catalyses the only known de novo pathway for the production of all four deoxyribonucleotides that are required for DNA synthesis1,2.It is essential for all organisms that use DNA as their ...
关键词:RADICAL DINUCLEAR synthesis 
整合素靶向肽促进SD大鼠骨髓间充质干细胞的增殖被引量:3
《中国组织工程研究》2022年第30期4780-4786,共7页贾麒钰 黄晓夏 郭建 黄金勇 郭晓斌 阿卜杜萨拉木·阿力木江 吴桐 马创 
新疆维吾尔自治区自然科学基金(2020D01C263),项目负责人:郭晓斌;国家自然科学基金(81760397),项目负责人:马创。
背景:研究报道整合素靶向肽多巴胺-精氨酸-甘氨酸-天冬氨酸(dopamine-arginine-glycine-aspatic acid,DOPA-RGD)可以抑制破骨细胞活化和促进细胞黏附,然而对于整合素靶向肽干预骨髓间充质干细胞或改性钛基材料的最适浓度及最适时间尚不...
关键词:整合素 DOPA-RGD肽 整合素靶向肽 骨髓间充质干细胞 细胞增殖 细胞迁徙 牵张成骨 大鼠 
Activation of mesocorticolimbic dopamine projections initiates cue-induced reinstatement of reward seeking in mice被引量:1
《Acta Pharmacologica Sinica》2022年第9期2276-2288,共13页Man-yi Jing Xiao-yan Ding Xiao Han Tai-yun Zhao Min-min Luo Ning Wu Jin Li Rui Song 
This work was supported by the National Natural Science Foundation of China(81573405 and U1502225);Natural Science Foundation of Beijing(7212159);National Key R&D Program of China(2016YFC0800907);National Key R&D Program of China(2017YFC131040);Medical Innovation Program(16CXZ033);Beijing Nova Program(xx2014A014).
Drug addiction is characterized by relapse when addicts are re-exposed to drug-associated environmental cues,but the neural mechanisms underlying cue-induced relapse are unclear.In the present study we investigated th...
关键词:drug addiction DOPAMINE ventral tegmental area nucleus accumbens medial prefrontal cortex optogenetic optical intracranial self-stimulation cocaine self-administration 
In situ growth of polydopamine on surface of covalent organic frameworks under the catalysis of acid phosphatase for dopamine detection
《Chinese Chemical Letters》2021年第11期3368-3371,共4页Fei Qu Ziwei Guo Dafeng Jiang Xian-En Zhao 
supported by the Natural Science Foundation of Shandong Province,China(No.ZR2019QB010);National Natural Science Foundation of China(Nos.21705095,21775088);the Scientific Research Foundation of Qufu Normal University(No.BS D20130117).
Dopamine(DA)is easy to be oxidized and polymerizes to form polydopamine(pDA)in alkaline conditions,while the synthesis is usually time-consuming(48 h).Herein,the polymerization of DA is completed with 4 h under the ca...
关键词:FLUORESCENCE ENZYME POLYDOPAMINE DOPAMINE Acid phosphatase 
Flexible dopamine-sensing fiber based on potentiometric method for long-term detection in vivo被引量:1
《Science China Chemistry》2021年第10期1763-1769,共7页Liyuan Wang Jiawei Chen Jiajia Wang Hongjian Li Chuanrui Chen Jianyou Feng Yue Guo Hongbo Yu Xuemei Sun Huisheng Peng 
the National Natural Science Foundation of China(22075050,21634003);the Ministry of Science and Technology of China(2016YFA0203302);the Science and Technology Commission of Shanghai Municipality(20JC1414902);Shanghai Municipal Education Commission(2017-01-07-00-07-E00062)。
Achieving real-time,continuous and long-term monitoring of dopamine(DA)in vivo is essential for revealing brain functions and preventing and treating neurogenic diseases.However,it remains challenging to achieve a low...
关键词:carbon nanotube fiber POTENTIOMETRIC IMPLANTABLE LONG-TERM dopamine detection 
儿童脑肿瘤氨基酸PET显像的研究进展
《上海交通大学学报(医学版)》2021年第7期949-952,共4页刘子豪 唐文芳 王辉 
国家自然科学基金(51673116,81974269,51703126)。
脑肿瘤是儿童肿瘤中最常见的实体肿瘤,也是儿童肿瘤致死的首要原因。常规磁共振成像(magnetic resonance imaging,MRI)在儿童脑肿瘤的诊断、治疗管理及预后评估等方面存在一定的不足。正电子发射断层显像(positron emission tomography,...
关键词:儿童 脑肿瘤 正电子发射断层显像/计算机断层扫描(PET/CT) 正电子发射断层显像/磁共振成像(PET/MRI) L-甲基-^(11)C-甲硫氨酸(^(11)C-MET) ^(18)F-乙基酪氨酸(^(18)F-FET) ^(18)F-二羟基苯丙氨酸(^(18)F-DOPA) 
Upconversion-luminescent hydrogel optical probe for in situ dopamine monitoring被引量:1
《Photonics Research》2020年第11期1800-1807,共8页Bingqian Zhou Jingjing Guo Changxi Yang Lingjie Kong 
National Natural Science Foundation of China(61805126);Tsinghua University Initiative Scientific Research Program(20193080076).
Dopamine(DA),as a neurotransmitter in human brain,plays a crucial role in reward motivation and motor control.An improper level of DA can be associated with neurological disorders such as schizophrenia and Parkinson’...
关键词:holds ATTRACTIVE enable 
“Buyi Ganshen”,a traditional Chinese medicine treatment,combined with dopa preparation for Parkinson’s disease therapy:a meta-analysis of randomized controlled trials
《TMR Aging》2020年第3期97-109,共13页Xiao-Qian Hao Wen-Wen Si Ye Tian Jie Liu Yi-Chun Ji Xin-Rong Li Zi-Feng Huang Yu Zhu Dong-Feng Chen Wei-Hong Kuang Mei-Ling Zhu 
This study was financially supported by TCM Administration Project of Guangdong Province,China(No.20203010);Science and Technology Program of Guangdong,China(No.2020A151501325).
Traditional Chinese medicine Buyi Ganshen therapy combined with dopa preparation in the therapy of Parkinson’s disease could enhance the clinical safety and efficacy compared with dopa preparation along.The exact mec...
关键词:Parkinson’s disease Buyi Ganshen Dopa preparation META-ANALYSIS 
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